Clinicopathological study of soft tissue sarcoma-retrospective study of tertiary cancer institute in eastern India

Background: Soft tissue sarcomas are a rare and heterogeneous group of malignant tumors of mesenchymal origin that comprise less than 1 percent of all adult malignancies. Although they occur anywhere in the body, they involve most commonly in extremities, trunk, retroperitoneum and head and neck. The aim of the study was to analyze clinical and histopathological features of various soft tissue sarcomas.Methods: This was a retrospective study, conducted in tertiary cancer centre in Odisha during the period 2015 to 2018. We collected clinical parameters like age, sex, site of swelling, any associated pain and biopsy reports and these variables were correlated with final histopathology reports.Results: A total of 107 patients were included in the study, with male to female ratio of 2:1(71 and 36) and average age of 43.45 years. All of them presented with a swelling. The lower extremities were the most common sites i.e. 44.62%. Pleomorphic sarcoma was the most frequent histologic variety comprising 43% and less frequent variety were angiosarcoma, and myxoid sarcoma.Conclusions: Soft tissue sarcoma are predominant in males and middle aged population are frequently affected. Most common affected site is lower extremity and pleomorphic sarcoma is the prominent histologic type.

Construction and Grouping of a Chinese People’s Armed Police Forces Provincial-Level Mobile Rescue Hospital System

In recent years, with the increasingly frequent variety of large-scale disasters that have happened in China, the Chinese People’s Armed Police Forces (PAP) has undertaken increasingly frequent and diversified tasks, which has led to greater requirements for the construction of emergency medical rescue equipment. Therefore, as determined by the characteristics of the PAP’s tasks and based on the construction of special boxes and frame tent equipment, a new PAP mobile rescue hospital system was successfully developed, and all PAP provincial-level medical rescue teams have been equipped with this system. In the present article, we describe this mobile rescue hospital system, which is mainly composed of professional emergency vehicles, frame-type tents, and advanced medical equipment. The system has the following characteristics: significant integration, a fast response, flexibility, and practicability. The mobile rescue system is generally used as the army’s own health service support system and to provide certain emergency medical rescue services to disaster-stricken people. The successful construction and further application of this system have significance in terms of accelerating the response of rescue teams and the emergency treatment ability of the PAP’s provincial-level emergency medical rescue teams. (Disaster Med Public Health Preparedness. 2018;12:455–459)

The architecture of an alluvial suite: rocks between the Townsend Tuff and Pickard Bay Tuff Beds (early Devonian), southwest Wales

The Townsend Tuff Bed and the Pickard Bay Tuff Bed are distinctive ash-fall tuffs traceable within a red-bed sequence over an area measuring about 35 km from west to east by 12 km from south to north. The succession between these markers is a mere 15-30 m thick, but contains six other tuffs which, though not themselves distinctive, can also be traced over the area by virtue of their position relative to the two main falls. The mudstone-dominated succession between the two main markers contains eight calcretes (pedogenic limestones), most of which extend over practically the whole of the area, and 16 generally local upward-fining or ‘coarse’ sequences composed of sandstones overlying an erosion surface and passing up into mudstones. The mudstones are massive and seldom laminated, apparently having been organically destratified. The coarser-grained upward-fining sequences involve cross-bedded, parallel-laminated and cross-laminated sandstones, whereas the finer-grained examples normally consist of interbedded mudstones and sharp-based cross-laminated sandstones. Intraformational conglomerates and stringers of mudstone clasts not infrequently accompany the coarser sandstones. Evidence of subaerial exposure is common towards the tops of both the coarser- and finer-grained sorts of upwardfining sequence. The careful tracing of the marker tuffs shows the upward-fining sequences to be of two main kinds. Examples of the least common type occur within localized and relatively deep depressions, probably incised valleys, which they fill to a height less than the depth of the depression. The more frequent variety is also localized but not obviously incised, having apparently grown up in harmony with the accumulation of mud in the area as a whole. The succession between the Townsend Tuff and Pickard Bay Tuff Beds lies in the transition between a clearly marine-influenced facies below and a clearly fluviatile facies above. It appears to record an extensive but comparatively featureless marginal mudflat influenced by both rivers and the sea. The development of calcretes (fossil soils) within the muddy sediments, and the shifting and valley-building activities of mixed tidal and river channels, could have been under the control of relative fluctuations of sea level perhaps on as short a time scale as of the order of 10 4 years. The channellized currents seem typically to have been vigorous and of low to moderate sinuosity.

MORPHOLOGICAL AND PATHOGENIC VARIATIONS IN TREPONEMA PALLIDUM

When many cultures of Treponema pallidum, whether obtained from the testicular lesions produced in rabbits or directly from human cases of syphilis, are compared, certain definite differences in morphological character become apparent. The different specimens can be divided into thicker and thinner forms or types, and an average or normal form or type. The last is the common or most frequent variety, but the other two occur with sufficient frequency and retain their characters with such constancy as to constitute distinct varieties. Indeed, two of the varieties—the average and the thinner—occurred in association in a chancre and were separated afterwards in cultures. The gross cultural properties of the three varieties present no points of distinction. The lesions caused in the testicle of the rabbit differ according to the variety inoculated, and consist either of a diffuse or of a nodular orchitis. This is a highly important distinction, and if, in the study of a still larger number of specimens of pallida, it is maintained, it is capable of throwing light on certain important clinical features of the human syphilitic disease. The thinner variety of Treponema pallidum resembles in morphology Treponema microdentium, from which it is unmistakably distinguished by cultural characters. The morphological and pathogenic variations in cultures of the pallidum may constitute racial differences within the species.

Case of Double Sacculated Intra-cranial Aneurysm

Authorities are very much at variance as to the most frequent variety of intra-cranial aneurysm; Erichsen states that they “are almost always formed by the uniform dilatation of a limited portion of the artery—the sacculated variety being rarely met with.” Treves is impartial, while in Osier's series of twelve cases, eleven were sacculated. They are rarely met with in the asylum post-mortem room, the mental symptoms commonly produced being simple irritability, restlessness, or depression of spirits, very rarely definite insanity as in the following case.

MONODONTOMERUS IN APPALACHIA

Monodontomerus stigma (Fabr.).M. viridæneus, Prov., Canada.Common in New England. In the District of Columbia I have reared it from the cell of Militoma euglossoides, var. taurea, Say.The genus Oligosthenus cannot remain separated, the fine dentitions of hind femora king more or less indistinct.A frequent variety has no cloud about stigma. The abdomen varies in the amount of purple.