Effects of low laser level therapy in rehabilitation of patients with COVID19 pneumonia

Introduction. An unprecedented public health crisis has been triggered worldwide by SARS-CoV-2’s high contagiosity and it’s mortality rates of 1-5%. Although the majority of COVID-19 cases have a good outcome, there is a small percentage that develop severe pneumonia and citokine storm and may be in the need of mechanical ventilation. Methods. Identifying the exact drivers of the excessive inflammation and the biomarkers that can predict a hyperinflammatory response to SARS-CoV-2 would be extremly helpful in finding efficient anti-inflammatory interventions that may stop the progression to acute respiratory distress syndrome (ARDS). Results. In the search for such interventions we have identified the promising effect of low level LASER therapy (LLLT) on lung inflammation from COVID-19 pneumonia. Due to its well known anti-inflammatory effect and modulatory activity on immune cells, laser therapy may be able to decrease lung and systemic inflammation without affecting lung function in acute lung lesions, relieve respiratory symptoms, normalize respiratory function and stimulate the healing process of lung tissue. The recovery time may also be significantly shortened and all blood, immunological and radiological parameters may improve. Conclusions. This findings need further confirmation from clinical trials but we are hopeful for their contribution on the global battle against COVID-19 pandemic. Keywords: SARS-CoV-2, pneumonia, low LASER level therapy, anti-inflammatory effect, citokine storm,

The Significance of Carrier Leakage for Stable Lasing in Split-Well Direct Phonon Terahertz Quantum Cascade Lasers

We studied the temperature performance of split-well direct phonon terahertz quantum cascade lasers and found that it is limited by a lasing instability that becomes significant as the temperature increases. When the hot electrons of the upper laser level cannot scatter effectively to excited states due to the high radiative barriers of the structures, a lasing instability occurs, which limits the temperature performance.

Влияние концентрации фосфатов на спектральные свойства ионов тулия во фторфосфатных стеклах

The Jadd-Ofelt parameters for thulium ions in fluorophosphate glasses with different phosphate content are calculated. The proximity of the values of the parameters Ωt of glasses with a content of up to 10 mol% Ba(PO3)2 to the similar parameters of the fluoride glasses and a sharp increase in their values with a further increase in phosphates are shown. In the framework of the Jadd-Ofelt theory, the spectral-luminescent parameters of glasses are analyzed. The spontaneous transitions probabilities, branching coefficients (β), and radiation lifetimes (τrad) for various excited states of Tm3+ ions are obtained. It was found that, at low phosphate concentrations, glasses have a high radiation lifetime for the excited 3F4 laser level. It has been shown that the glasses with a content of up to 10 mol% Ba(PO3)2 are characterized by a wide flat gain spectrum, which makes them promising materials for creating broadband amplifiers.