cation diffusion facilitator family
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2019 ◽  
Vol 202 (1) ◽  
Author(s):  
Matthew J. Johnsrude ◽  
Joshua E. Pitzer ◽  
Daniel W. Martin ◽  
R. Martin Roop

Mn nutrition is essential for the basic physiology and virulence of Brucella strains. The results of the study presented here demonstrate that the cation diffusion facilitator (CDF)-type metal exporter EmfA plays critical roles in maintaining Mn homeostasis and preventing Mn toxicity in Brucella and is an essential virulence determinant for these bacteria. EmfA and other cellular components involved in Mn homeostasis represent attractive targets for the development of improved vaccines and chemotherapeutic strategies for preventing and treating brucellosis in humans and animals.


Planta ◽  
2018 ◽  
Vol 248 (1) ◽  
pp. 231-241 ◽  
Author(s):  
Yuta Tsunemitsu ◽  
Mayuko Genga ◽  
Tomoyuki Okada ◽  
Naoki Yamaji ◽  
Jian Feng Ma ◽  
...  

FEBS Letters ◽  
2015 ◽  
Vol 589 (12) ◽  
pp. 1283-1295 ◽  
Author(s):  
Olga Kolaj-Robin ◽  
David Russell ◽  
Kevin A. Hayes ◽  
J. Tony Pembroke ◽  
Tewfik Soulimane

2013 ◽  
Vol 64 (14) ◽  
pp. 4375-4387 ◽  
Author(s):  
Zonghui Chen ◽  
Yumi Fujii ◽  
Naoki Yamaji ◽  
Sakine Masuda ◽  
Yuma Takemoto ◽  
...  

2009 ◽  
Vol 76 (3) ◽  
pp. 768-771 ◽  
Author(s):  
Takashi Higuchi ◽  
Motoyuki Hattori ◽  
Yoshiki Tanaka ◽  
Ryuichiro Ishitani ◽  
Osamu Nureki

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