Chapter 119 discusses imaging artifacts in musculoskeletal US. Artifacts may be produced with B-mode grayscale and Doppler US imaging. These artifacts occur when the US beam deviates from ideal physical beam assumptions. It is important for radiologists to have an understanding of these artifacts so as to distinguish them from pathology. Side lobe, beam-width, posterior acoustic enhancement and shadowing, posterior reverberation, ring down, comet-tail, mirror image, anisotropy, refraction, and speed displacement artifacts are seen with grayscale imaging. Background noise, mirror image, aliasing, twinkle, transducer pressure, motion, and blooming artifacts are seen with Doppler imaging. Understanding of US artifacts is crucial to avoid mistaking artifacts for true pathology.