The Biological Effectiveness and Medical Significance of Far Infrared Radiation (FIR)

The electromagnetic waves constitute different wavelengths of light from which Far infrared (FIR) is beneficial for living cells. Extensive studies and trials have been conducted over the last two decades in multidimensional biological domains to identify its unlimited health benefits. FIR radiations improve the microcirculation of the human body, stimulate cell growth, penetrate through skin tissues non-invasively, create intramolecular vibrations create an overall healthy metabolism, which ultimately affects overall improved cardiac and metabolic activity. This phenomenon is used to explore different pathological conditions to identify their significance in the medical field. In this review, we explored the biological effectiveness and the medical significance of Far infrared radiation (FIR) in murine melanoma Cell Growth, Lymphedema, airborne viruses, Cardiac diseases, Wound healing and burns, Autonomic Activities, Hemodialysis, Allergic Rhinitis, Aesthetic medicine, textiles, and other domains such as obesity and gut microbiota.

MANIFESTATION OF INTRAMOLECULAR VIBRATIONS IN THE FLUORESCENCE SPECTRA OF MOLECULES IN POLAR MEDIA

The effect of a low frequency intramolecular vibration on the nonstationary fluorescence spectrum of a molecule and the dynamics of the Stokes shift is analyzed in the framework of the nonstationary perturbation theory based on the operator of the interaction energy of the electric field of the exciting pump pulse with a dissolved molecule. Using a well-tested spin-boson model, which takes into account not only the reorganization of the relaxation polarization modes of the medium, but also intramolecular vibrations, an analytical expression for the time-resolved fluorescence signal is written, and the conditions under which the oscillations of the maximum of nonstationary fluorescence spectra can manifest themselves are analyzed. It is shown that the reorganization of the medium does not suppress the oscillations of the spectrum maximum.

Aggregation-Induced Emission: A Challenge for Computational Chemistry. the Example of TPA-BMO.

A multi-scale and multi-environment computational approach is proposed to study of the modulation of the emission behavior of the triphenylamine (Z)-4-benzylidene-2-methyloxazol-5(4H)-one (TPA-BMO) molecule [Tang <i>et al</i>., J. Phys. Chem. C,<b>119</b>, 21875 (2015)]. Going from (TD-)DFT calculations to classical Molecular Dynamics simulations through the hybrid ONIOM QM/QM’ approach and the <i> </i><i>in situ</i> chemical polymerization methodology, we have rationalized distinct photophysical phenomena: (1) in low-polar solvents, a polarity-dependent solvatochromic effect as well as a modulation of the emission quantum yield, attributed to possible photophysical energy dissipation caused by low-frequency vibrational modes, (2) in the aggregate, a subtle competition between an excitonic coupling and a restriction of the intramolecular vibrations leading to an Aggregation-Induced Emission behavior, and (3) in the polymer matrix, an antagonist effect between the loss of global flexibility and the presence of vibrational modes similar to those observed in solution, explaining a similar emissive behavior within the polymer.<p></p>

Aggregation-Induced Emission: A Challenge for Computational Chemistry. the Example of TPA-BMO.

A multi-scale and multi-environment computational approach is proposed to study of the modulation of the emission behavior of the triphenylamine (Z)-4-benzylidene-2-methyloxazol-5(4H)-one (TPA-BMO) molecule [Tang <i>et al</i>., J. Phys. Chem. C,<b>119</b>, 21875 (2015)]. Going from (TD-)DFT calculations to classical Molecular Dynamics simulations through the hybrid ONIOM QM/QM’ approach and the <i> </i><i>in situ</i> chemical polymerization methodology, we have rationalized distinct photophysical phenomena: (1) in low-polar solvents, a polarity-dependent solvatochromic effect as well as a modulation of the emission quantum yield, attributed to possible photophysical energy dissipation caused by low-frequency vibrational modes, (2) in the aggregate, a subtle competition between an excitonic coupling and a restriction of the intramolecular vibrations leading to an Aggregation-Induced Emission behavior, and (3) in the polymer matrix, an antagonist effect between the loss of global flexibility and the presence of vibrational modes similar to those observed in solution, explaining a similar emissive behavior within the polymer.<p></p>