Mucinous Cystadenoma of the Ovary Associated with Hyperplasia of Stromal Leydig Cells in Pregnant Woman

Background: The hormonally induced non-neoplastic lesions of ovarian stroma during pregnancy must be recognized by pathologist in order to avoid mistaking them for true tumors. Case report: A 28-year-old woman was delivered of a healthy infant by cesarean section. As an incidental finding, a multicystic tumor in the left ovary was found and resected. Histopathology was consistent with benign mucinous cystadenoma. In addition, within the stroma beneath the lining mucinous epithelium, a dense population of cohesive polygonal cells with abundant eosinophilic cytoplasm, typically resembling the Leydig cells, was seen. They were uniform without atypia, accompaning by minimal proliferative activity. They strongly expressed vimentin, inhibin, CD99 and calretinin. The final diagnosis of mucinous cystadenoma associated with hyperplasia of stromal Leydig cells was made. Conclusions: Leydig cell hyperplasia belongs to the specific changes of ovarian stroma associated with pregnancy. The present case stresses that in such situation the pathologists should be aware of it and not confuse it with a tumor.

Unilateral Straight Hair—A Symptom of Acquired Horner's Syndrome in a Neonate

A multicystic tumor of the right neck was detected in a girl at 29 weeks of gestation by fetal ultrasound and magnetic resonance imaging (MRI). The baby was delivered by cesarean section at week 37 of gestation. The newborn adapted well, with minimal compromise of breathing and drinking. Postnatal ultrasound and MRI revealed a cervical lymphangioma measuring 60.5 × 60.6 × 41.2 mm. We performed subtotal resection of the tumor when the girl was 34 days. As a complication of surgical resection, the girl developed ipsilateral Horner's syndrome. In the postoperative period, her curled hair turned straight at the side of the head affected by Horner's syndrome. At the age of 2.5 years, ultrasonic imaging revealed the presence of three cysts measuring 3 mm in diameter each. Horner's syndrome had improved, and the texture of the girl's hair had become curly again on both sides.

Surgical Management of Tailgut Cysts: A Report of Two Cases

A tailgut cyst is an uncommon congenital developmental cyst that arises from the postnatal remnants of the primitive gut. These cysts are generally located in the retrorectal space. The rarity of this lesion and its anatomical position frequently lead to difficulties in its diagnosis and surgical management. Complete surgical resection remains the cornerstone of treatment, and numerous surgical approaches to achieve this objective have been described in the literature. We present 2 cases of tailgut cysts that were resected using a trans-sacral approach. We discuss the surgical management of these cases, including the operative approach that was adopted. Two cases of tailgut cysts that presented as incidentally detected retrorectal tumors are described here. A pelvic magnetic resonance imaging scan revealed a retrorectal multicystic tumor consistent with a tailgut cyst. The patients underwent surgery via a trans-sacral approach with coccygectomy. The histopathologic diagnosis for each patient was a tailgut cyst with no evidence of malignancy. Surgical approaches for tailgut cysts depend on the exact locations of the cysts and suspicions regarding the malignancies of the cysts. En bloc organ resection, including coccygectomy, is required if malignancy is suspected. We endorse the trans-sacral approach as a feasible, easy to perform, minimally invasive, and safe option for treating relatively low-lying tailgut cysts.

Laparoscopically Resected Foregut Cyst Adjacent to the Right Adrenal Gland

A case of 49-year-old woman with a retroperitoneal undifferentiated foregut cyst attached to the right adrenal gland is reported. The bronchogenic cyst is a type of foregut cyst with a cartilage component, but in this case the multicystic tumor lacked both cartilage and gland. It is quite rare among retroperitoneal tumors and has not been reported so far to have malignant potential. The preoperative diagnosis was an adrenal benign incidentaloma, and the patient successfully underwent laparoscopic resection of the cystic tumor together with the right adrenal gland by lateral transabdominal approach. Laparoscopic surgery for a retroperitoneal tumor is problematic, however, since benignancy cannot be predicted. In laparoscopic adrenalectomy for non-functioning adrenal tumor, therefore, a differential diagnosis from retroperitoneal tumor should be given serious consideration.