Cue overlap supports preretrieval selection in episodic memory: ERP evidence

People often want to recall events of a particular kind, but this selective remembering is not always possible. We contrasted two candidate mechanisms: the overlap between retrieval cues and stored memory traces, and the ease of recollection. In two preregistered experiments (Ns = 28), we used event-related potentials (ERPs) to quantify selection occurring before retrieval and the goal states — retrieval orientations — thought to achieve this selection. Participants viewed object pictures or heard object names, and one of these sources was designated as targets in each memory test. We manipulated cue overlap by probing memory with visual names (Experiment 1) or line drawings (Experiment 2). Results revealed that regardless of which source was targeted, the left parietal ERP effect indexing recollection was selective when test cues overlapped more with the targeted than non-targeted information, despite consistently better memory for pictures. ERPs for unstudied items also were more positive-going when cue overlap was high, suggesting that engagement of retrieval orientations reflected availability of external cues matching the targeted source. The data support the view that selection can act before recollection if there is sufficient overlap between retrieval cues and targeted versus competing memory traces.

Ruins, rhizomes, palimpsests, and traces-mémoires: Guadeloupe’s Mémorial ACTe and the art(s) of representation

This study examines the degree to which the world’s largest slavery memorial and arts center enacts emerging theorizations of postcolonial memory to connect the Caribbean’s colonial history to legacies of human exploitation both transnationally and transtemporally. Situated literally on top of the former Darboussier sugar factory site, the Mémorial ACTe is a lieu de mémoire that invites a palimpsestic approach to its symbolic location, architecture, and museography. Through a consideration of contemporary art, first in the ephemeral occupation by artists of the Darboussier ruins pre-demolition and then in the MACTe’s permanent and temporary exhibitions, we argue that artists are not only uniquely positioned to preserve the memory traces of lesser-known histories, but that their work is particularly adept at articulating interconnections between various moments of racialized violence.

Interpreting Developmental Surface Dyslexia within a Comorbidity Perspective

Recent evidence underlines the importance of seeing learning disorders in terms of their partial association (comorbidity). The present concept paper presents a model of reading that aims to account for performance on a naturalistic reading task within a comorbidity perspective. The model capitalizes on the distinction between three independent levels of analysis: competence, performance, and acquisition: Competence denotes the ability to master orthographic–phonological binding skills; performance refers to the ability to read following specific task requirements, such as scanning the text from left to right. Both competence and performance are acquired through practice. Practice is also essential for the consolidation of item-specific memory traces (or instances), a process which favors automatic processing. It is proposed that this perspective might help in understanding surface dyslexia, a reading profile that has provoked a prolonged debate among advocates of traditional models of reading. The proposed reading model proposes that surface dyslexia is due to a defective ability to consolidate specific traces or instances. In this vein, it is a “real” deficit, in the sense that it is not due to an artifact (such as limited exposure to print); however, as it is a cross-domain defect extending to other learning behaviors, such as spelling and math, it does not represent a difficulty specific to reading. Recent evidence providing initial support for this hypothesis is provided. Overall, it is proposed that viewing reading in a comorbidity perspective might help better understand surface dyslexia and might encourage research on the association between surface dyslexia and other learning disorders.

Where was the Toaster? Interplay of Episodic Memory Traces and Semantic Knowledge during Scenario Construction

Experiences that are retrieved from memory are often not accurate, but prone to biases. The interplay of already existing semantic knowledge and recently generated episodic memory traces might explain some of the underlying mechanisms. The scenario construction model postulates that during encoding, only the gist of an episode is stored in the episodic memory trace and during retrieval, any needed information that is missing from that trace is constructed from semantic knowledge. The current study aimed to investigate semantic construction in a realistic, yet controlled setting. Using a desktop virtual reality (VR) participants navigated through a flat in which some household items appeared in unexpected rooms, creating conflicts between the experienced episode and semantic expectations. During recall after two separate retrieval delays (one day vs one week) we were able to identify influences from semantic knowledge. To manipulate salience, some objects were task-relevant, and some were irrelevant to the sequence of actions. We used spatial and temporal recall measures. Both congruency and task-relevance, but not time, predicted correct episodic memory retrieval. In the spatial memory retrieval, semantic construction was more likely than guessing in cases of episodic memory failure and occurred more frequently for task-irrelevant objects. In the temporal recall at the second retrieval delay we could show that object-pairs belonging to the same semantic room-category were temporally clustered together compared to object-pairs from different semantic room-categories. Taken together, our findings support the predictions of the scenario construction model, as we found influences of semantic knowledge on both spatial and temporal memory recall. The new VR-paradigm appears to be a promising tool for investigating semantic construction.

Mnemonic prediction errors promote detailed memories

When our experience violates our predictions, it is adaptive to update our knowledge to promote a more accurate representation of the world and facilitate future predictions. Theoretical models propose that these mnemonic prediction errors should be encoded into a distinct memory trace to prevent interference with previous, conflicting memories. We investigated this proposal by repeatedly exposing participants to pairs of sequentially presented objects (A → B), thus evoking expectations. Then, we violated participants’ expectations by replacing the second object in the pairs with a novel object (A → C). The following item memory test required participants to discriminate between identical old items and similar lures, thus testing detailed and distinctive item memory representations. In two experiments, mnemonic prediction errors enhanced item memory: Participants correctly identified more old items as old when those items violated expectations during learning, compared with items that did not violate expectations. This memory enhancement for C items was only observed when participants later showed intact memory for the related A → B pairs, suggesting that strong predictions are required to facilitate memory for violations. Following up on this, a third experiment reduced prediction strength prior to violation and subsequently eliminated the memory advantage of violations. Interestingly, mnemonic prediction errors did not increase gist-based mistakes of identifying old items as similar lures or identifying similar lures as old. Enhanced item memory in the absence of gist-based mistakes suggests that violations enhanced memory for items’ details, which could be mediated via distinct memory traces. Together, these results advance our knowledge of how mnemonic prediction errors promote memory formation.

Prior Exposure and Toddlers’ Sleep-Related Memory for Novel Words

Children can easily link a novel word to a novel, unnamed object—something referred to as fast mapping. Despite the ease and speed with which children do this, their memories for novel fast-mapped words can be poor unless they receive memory supports such as further exposure to the words or sleep. Axelsson, Swinton, Winiger, and Horst (2018) found that 2.5-year-old children who napped after fast mapping had better retention of novel words than children who did not nap. Retention declined for those who did not nap. The children received no memory supports and determined the word–object mappings independently. Previous studies report enhanced memories after sleeping in children and adults, but the napping children’s retention in the Axelsson et al. study remained steady across time. We report a follow-up investigation where memory supports are provided after fast mapping to test whether memories would be enhanced following napping. Children’s retention of novel words improved and remained greater than chance; however, there was no nap effect with no significant difference between the children who napped and those who did not. These findings suggest that when memory supports are provided, retention improves, and the word–object mappings remain stable over time. When memory traces are weak and labile, such as after fast mapping, without further memory supports, sleeping soon after helps stabilise and prevent decay of word–object mappings.

Representing Integer Sequences Using Piecewise-Affine Loops

A formal, high-level representation of programs is typically needed for static and dynamic analyses performed by compilers. However, the source code of target applications is not always available in an analyzable form, e.g., to protect intellectual property. To reason on such applications, it becomes necessary to build models from observations of its execution. This paper details an algebraic approach which, taking as input the trace of memory addresses accessed by a single memory reference, synthesizes an affine loop with a single perfectly nested reference that generates the original trace. This approach is extended to support the synthesis of unions of affine loops, useful for minimally modeling traces generated by automatic transformations of polyhedral programs, such as tiling. The resulting system is capable of processing hundreds of gigabytes of trace data in minutes, minimally reconstructing 100% of the static control parts in PolyBench/C applications and 99.99% in the Pluto-tiled versions of these benchmarks. As an application example of the trace modeling method, trace compression is explored. The affine representations built for the memory traces of PolyBench/C codes achieve compression factors of the order of 106 and 103 with respect to gzip for the original and tiled versions of the traces, respectively.

Spinal reconsolidation engages non-ionotropic NMDA receptor signaling to reverse pain hypersensitivity

Reconsolidation enables the activity-dependent modification of memory traces and has been used to reverse addiction, fear memory, and pain hypersensitivity in animal models. We demonstrate that non-ionotropic NMDA receptor signalling in the spinal dorsal horn is sufficient to reverse pain hypersensitivity and necessary for pain modulation by spinal reconsolidation. These findings reveal a key process by which reconsolidation weakens memory traces that may be exploited in the treatment of pain and other disorders.