Simultaneous transoral parathyroidectomy and laparoscopic pancreatic resection in type 1 Multiple Endocrine Neoplasia syndrome

The article presents a clinical observation of a patient with type 1 Multiple Endocrine Neoplasia syndrome (MEN 1). During the diagnostic search, a combination of primary hyperparathyroidism, parathyroid adenoma and hormonally inactive pancreatic head tumor was found. Simultaneous transoral parathyroidectomy and laparoscopic resection of the pancreatic head was performed. We haven`t found the literature data describing such kind of operations for MEN 1 syndrome. An original solution was applied to perform intraoperative ultrasonography monitoring. The results of 1-year postoperative follow-up are presented. This observation demonstrates the possibilities of endoscopic technologies in the treatment of MEN 1 syndrome.

EXPERIENCE OF GASTROPANCREATODUODENAL RESECTION WITH CIRCULAR RESECTION OF MAJOR VENOUS VESSELS

Purpose of work. Improve patient outcomes in patients with pancreatic cancer.Material and methods of research. We present our own clinical observation of surgical treatment of malignant neoplasms of the head of the pancreas with invasion of the main venous vessels. In 2019, on the basis of 1 surgical Department of the GUZ Regional clinical oncological dispensary, 2 patients underwent gastropancreatoduodenal resections with circular portal vein resection and end-to-end angioplasty.The results of the study and their discussion. Tumor invasion into the main venous vessels is not a contraindication to performing radical surgery and is achievable when performing gastropancreatoduodenal resection, due to resections of the main venous vessels together with the tumor invading its wall.Conclusions. Resection of the portal vein together with the pancreatic head tumor invading its wall contributes to the achievement of radical surgery when performing gastropancreatoduodenal resection.

Timing of the termination of mechanical jaundice after antegrade and retrograde decompressive surgeries in mechanical jaundice of various genesis

Aim: to determine in a comparative aspect the effectiveness of various minimally invasive decompressive operations in mechanical jaundice of different genesis. Materials and methods. In 135 patients with mechanical jaundice, the rate of bile duct resolution after cholecystostomy and percutaneous cholangiostomy was studied on the background of pancreatic head tumor. In 643 patients with obstructive bile duct disease in cholelithiasis, timing of the termination of jaundice after minimally invasive retrograde (endoscopic papillosphincterotomy (EPT) and EPT with transpapillary drainage) and percutaneous antegrade (cholecystostomy and cholangiostomy) of decompressive operations was studied. Result. Upon cholelithiasis and hyperbilirubinemia less than 100 μmol/l, jaundice is terminated after both variants of retrograde decompression within 3–5 days, antegrade interventions increase these terms by half. Comparison of retrograde and antegrade decompressive surgeries in mechanical jaundice of medium and severe degree on the background of cholelithiasis indicates that the rate of termination of bile stasis is the highest after EPT with transpapillary drainage. Isolated EPT and percutaneous cholangiostoma with medium-grade gallstones increase the duration of jaundice termination by an average of one week. Upon hyperbilirubinemia more than 200 μmol/l, cholangiostomy is not worse than transpapillary drainage. The longest termination period of obstructive jaundice (28–30 days) is observed after superimposition of microcholecystostoma. In patients with jaundice of a mild degree of tumor genesis, no differences in the results were revealed after both variants of percutaneous decompression. Upon hyperbilirubinemia above 100 μmol/l, when cholangio- and cholecystostomy were compared, a higher rate of decrease in serum bilirubin was observed after percutaneous interventions with a cholecystostomy. Conclusion. At all severity levels of mechanical jaundice on the background of cholelithiasis, the best way of decompression is endoscopic papillotomy with transpapillary drainage. In obturation bile stasis upon the pancreatic head tumor, the best decompressive effect is observed after percutaneous cholecystoostomy.

One more anatomic variant of the celiac trunk(in French)

Anatomical variations of the celiac trunk are numerous. Variants of the hepatic artery are important to consider especially in the bilio-pancreatic procedures. Unusual arterial anatomy increases the risk of postoperative specific complications. We report a case of a rare anatomic variant of the celiac trunk that gives rise to a left and right hepatic artery separately. It is an exceptional variant found in a patient with a pancreatic head tumor and candidate for duodenopancreatectomy. Key words: celiac trunk, right hepatic artery, anatomic variant.

One more anatomic variant of the celiac trunk(in French)

Anatomical variations of the celiac trunk are numerous. Variants of the hepatic artery are important to consider especially in the bilio-pancreatic procedures. Unusual arterial anatomy increases the risk of postoperative specific complications. We report a case of a rare anatomic variant of the celiac trunk that gives rise to a left and right hepatic artery separately. It is an exceptional variant found in a patient with a pancreatic head tumor and candidate for duodenopancreatectomy. Key words: celiac trunk, right hepatic artery, anatomic variant.

A Case of Solid Pseudopapillary Neoplasm Spontaneously Ruptured Into the Duodenum: Case Report

There have been no reports of ruptured solid pseudopapillary neoplasm (SPN) into adjacent organs. A 22-year-old female was referred to our hospital for treatment of a pancreatic head tumor. Computed tomography (CT) examination at our hospital showed a 5-cm tumor containing air, although CT at a previous hospital revealed an 8-cm tumor without air. Thus, a spontaneous rupture of the tumor into the duodenum was suspected. Subtotal stomach preserving pancreaticoduodenectomy with combined resection of the portal vein was performed. Contrast radiography of resected specimen showed the medium injected into the tumor leaking out from the 2nd portion of the duodenum. Histologically, the patient was diagnosed as SPN. Microscopic invasion to the portal vein and duodenum were also confirmed. She did not experience any postoperative complications and has remained well without any signs of recurrence during 2 years of follow-up. Although there have been 14 studies reporting ruptured SPN, this is the first report of SPN that spontaneously ruptured into the duodenum. An extremely rare case of SPN of the pancreatic head that spontaneously ruptured into the duodenum was reported.

Postoperative Lymphorrhagia- a Possible Complication Following Cephalic Duodenopancreatectomy

Surgery associated with lymphadenectomy may sometimes result in a lymphorrhagia, which usually resolves spontaneously within a few days, sometimes becoming a refractory complication to the treatment. In the case of large flows, particular attention should be paid to hydro-electrolytic and protein losses. We present the case of a patient with persistent lymphorrhagia after a cephalic duodenopancreatectomy for a pancreatic head tumor. From the 5th postoperative day, the patient had a milky-like secretion on the subhepatic drainage tube. The discharge rate was variable, between 500 and 1500 ml per day, requiring parenteral administration of amino acids, plasma and electrolyte solutions. The postoperative progression was slowly favorable, with the patient discharge on the 25th day following surgery. There are several treatment options for a lymphorrhagia following an extended lymphadenectomy, from intensive parenteral therapy to peritoneal-venous shunt or ligation of the lymphatic vessel responsible for the production of lymphorrhagia. In this case the conservative treatment had a favorable result.

Preliminary results of robotic pancreaticoduodenectomy at hepatobiliary-pancreatic surgery department – Cho Ray Hospital

Tóm tắt Đặt vấn đề: Cắt khối tá tụy là một trong những phẫu thuật ổ bụng khó nhất. Việc áp dụng phương pháp xâm lấn tối thiểu cho phẫu thuật này gặp nhiều khó khăn với dụng cụ nội soi cổ điển. Phẫu thuật nội soi với robot hỗ trợ giúp phẫu thuật trở nên dễ dàng hơn. Mục tiêu: Đánh giá kết quả sớm phẫu thuật robot cắt khối tá tụy Phương pháp nghiên cứu: Mô tả tiền cứu các trường hợp cắt khối tá tụy bằng robot tại khoa Ngoại gan mật tụy bệnh viện Chợ Rẫy Kết quả: Trong thời gian tháng 12/2017 đến tháng 3/2019, chúng tôi đã thực hiện 28 trường hợp cắt khối tá tụy bằng robot. Chẩn đoán trước mổ đa số là u bóng Vater (77%), u đoạn cuối ống mật chủ và u đầu tụy lần lượt chiếm 9% và 14%. Thời gian phẫu thuật trung bình là 522,5 phút. Chuyển mổ mở 2 trường hợp (7,1%). Điểm đau trung bình các ngày hậu phẫu theo VAS là 4. Có 6 trường hợp biến chứng nhẹ (Clavien-Dindo độ 1-2, 21,4%), 4 trường hợp biến chứng nặng (Clavien-Dindo độ 3-4, 14,3%), mổ lại 2 trường hợp (7,1%). Không có tử vong. Thời gian hậu phẫu trung bình là 16,4 ngày. Kết luận: Kết quả của nghiên cứu tương đồng với kết quả của các tác giả trên thế giới. Phẫu thuật robot cắt khối tá tụy được chứng minh là an toàn và khả thi. Abstract Introduction: Pancreaticoduodenectomy is one of most challenge of abdominal procedures. Application of minimal invasive surgery in this procedure encounters many difficulties with classic laparoscopic instruments. Robot- assisted surgery system refers minimal invasive surgery in pancreaticoduodenectomy easier. Material and Methods: Assess the preliminary results of robotic pancreaticoduodenectomy Results: From December 2017 to March 2019, we performed 28 cases of robotic pancreaticoduodenectomy. Preoperative diagnosis includes authors Vater tumors (77%), distal bile duct tumors (9%) and pancreatic head tumor (14%). Mean operative time was 522,5 minutes. Conversion rate was 7,1% (n=2). Average mean postoperative VAS score was 4. There was 6 cases of mild complications (Clavien-Dindo grade 1-2, 21,4%), 4 cases of severe complications (Clavien-Dindo grade 3-4, 14,3%), Reoperation in 2 cases (7,1%). No case of death was observed. Mean postoperative hospital stay were 16,4 days. Conclusion: Our results are similar to other authors in worldwide so we suggested that robotic pancreaticoduodenectomy was proved to be safe and feasible. Keywords: Laparoscopic D.P.C, Robotic surgery