Problem statement. Today, the world's leading researchers are working on the creation of objects on the surface of the Moon. One of the urgent tasks is to develop living modules that provide the necessary protection for the crew of the lunar missions. Analysis of existing research has shown that in order to support long-term surface missions, the lunar infrastructure must provide the necessary functionality of the housing base, such as extraction and processing of raw materials, construction, construction of buildings and structures, life support. Purpose of the article. Analysis of the current state of scientific and applied problems and setting goals and objectives of the further study. The subject of the study is to establish the patterns of lunar bases design and operation in the human civilization interests. Conclusions. The solution of the objectives of the study using the proposed systematic approach of creating an innovative dual-use product, namely, the development of building materials, products and structures by additive technologies (3D-printing) and recommendations for their production will allow the creation of high-security building projects that can be used for development of the Moon and the Earth, which will contribute to the development of domestic territorial and industrial infrastructure. The earth and lunar rocks are extremely similar, so the earth rock processing technologies can be applied to the lunar rocks. The development of the residential module and the structures design must take into account the complete life cycle of the lunar base facilities, as well as the physiological needs of the lunar base crew.