Primary Hyperparathyroidism - Experience at Mayo Hospital, Lahore

The retrospective study was carried out on surgical floor at Mayo Hospital, Lahore, over a span of 15 years. Twenty patients referred from various specialities were included in the study. Seven were male and 13 were female. All patients were diagnosed biochemically and localization was performed with the help of ultrasonography, thallium & technitum subtraction. All patients underwent surgical exploration by adopting four glands exposure technique. Sixteen having single adenoma, two patients having multiple adenoma and two as hyperplasia and no malignancy seen on the basis of histopathological examination. No significant morbidity and no mortality observed in the series.

Surgical treatment of primary hyperparathyroidism

Ninety patients (61 women and 29 men) aged 18—60 years with primary hyperparathyrosis (PH PT) of several months to 12 years standing were observed. Control group consisted of 20 normal subjects (15 women, 5 men) aged 18—60 years. Osseous PHPT was diagnosed in 51 patients: mild in 6, moderate in 30, and severe in 15 patients. Mixed PHPT 33 was diagnosed in 39 patients (mild in 8, moderate in 23, and severe in 8). Six types of interventions were used. Solitary adenoma was found in 44patients (48.8%), paired and multiple adenoma of the thyroid in 33 (36.6%), thyroid hyperplasia in 10 (11.1%), and carcinoma in 3 (3.3%) cases. Surgical treatment promoted recovery and restoration of working capacity in 74.4% patients during the first 6 months and in up to 92.3% during the next 3—6 months after reoperation for relapses and hypoparathyrosis.