Primary Hyperparathyroidism - Experience at Mayo Hospital, Lahore

The retrospective study was carried out on surgical floor at Mayo Hospital, Lahore, over a span of 15 years. Twenty patients referred from various specialities were included in the study. Seven were male and 13 were female. All patients were diagnosed biochemically and localization was performed with the help of ultrasonography, thallium & technitum subtraction. All patients underwent surgical exploration by adopting four glands exposure technique. Sixteen having single adenoma, two patients having multiple adenoma and two as hyperplasia and no malignancy seen on the basis of histopathological examination. No significant morbidity and no mortality observed in the series.

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The Technique of Intraoperative Nuclear Mapping to Facilitate Minimally Invasive Parathyroidectomy

Cancer Control ◽

10.1177/107327489700400603 ◽

1997 ◽

Vol 4 (6) ◽

pp. 500-504 ◽

Cited By ~ 21

Author(s):

James Norman

Keyword(s):

Primary Hyperparathyroidism ◽

Minimally Invasive ◽

Outpatient Setting ◽

Minimally Invasive Parathyroidectomy ◽

Invasive Technique ◽

Single Adenoma ◽

Surgical Exploration ◽

Invasive Parathyroidectomy ◽

Sestamibi Scan ◽

Sestamibi Scanning

Background Despite the fact that primary hyperparathyroidism (HPTH) is the result of a single adenoma in 85% to 92% of cases and is cured following the removal of this one gland, many surgeons continue to perform a complete bilateral neck exploration for patients with primary HPTH. The advent of the sestamibi scan now enables the identification of patients with a single adenoma. Methods The use of preoperative sestamibi scanning followed immediately by minimally invasive parathyroidectomy using intraoperative nuclear mapping allows cure for primary HPTH in properly selected patients. Results Reports have shown that preoperative sestamibi scanning has a sensitivity of approximately 90% and a specificity of almost 100% in identifying patients with a single adenoma. Intraoperative mapping allows a limited dissection to be performed under local anesthesia in an outpatient setting in approximately 80% of all patients with primary hyperparathyroidism. The details of this new technique — patient selection, timing, use of the intraoperative nuclear probe, and surgical exploration — are described. Conclusions When selected appropriately, most patients with primary HPTH can be successfully treated through a minimally invasive technique.

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Microwave ablation versus radiofrequency ablation for primary hyperparathyroidism: a multicenter retrospective study

International Journal of Hyperthermia ◽

10.1080/02656736.2021.1945689 ◽

2021 ◽

Vol 38 (1) ◽

pp. 1023-1030

Author(s):

Ying Wei ◽

Cheng-zhong Peng ◽

Shu-rong Wang ◽

Jun-feng He ◽

Li-li Peng ◽

...

Keyword(s):

Retrospective Study ◽

Radiofrequency Ablation ◽

Primary Hyperparathyroidism ◽

Microwave Ablation

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Association between serum magnesium and hemoglobin in primary hyperparathyroidism: A 10-year retrospective study

Bone Reports ◽

10.1016/j.bonr.2021.100922 ◽

2021 ◽

Vol 14 ◽

pp. 100922

Author(s):

Ding Na ◽

Guo Tao ◽

Liu ShuYing ◽

Wang QinYi ◽

Qu XiaoLi ◽

...

Keyword(s):

Retrospective Study ◽

Primary Hyperparathyroidism ◽

Serum Magnesium

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Retrospective study of effects of hypomagnesemia on severity of primary hyperparathyroidism

Bone Reports ◽

10.1016/j.bonr.2021.100921 ◽

2021 ◽

Vol 14 ◽

pp. 100921

Author(s):

Ding Na ◽

Tao Guo ◽

Liu ShuYing ◽

Wang QinYi ◽

Qu XiaoLi ◽

...

Keyword(s):

Retrospective Study ◽

Primary Hyperparathyroidism

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Computed Tomography and Bronchoscopy in Endobronchial Tuberculosis

Canadian Respiratory Journal ◽

10.1155/2003/496296 ◽

2003 ◽

Vol 10 (8) ◽

pp. 445-448 ◽

Cited By ~ 11

Author(s):

Halil Yanardag ◽

Cüneyt Tetikkurt ◽

Seza Tetikkurt ◽

Sabriye Demirci ◽

Tuncer Karayel

Keyword(s):

Computed Tomography ◽

Retrospective Study ◽

Therapeutic Response ◽

Histopathological Examination ◽

Computed Tomographic ◽

Before And After ◽

Endobronchial Tuberculosis ◽

Age Range

BACKGROUND: The therapeutic response to endobronchial tuberculosis is usually evaluated by bronchoscopy. Currently, there are no published studies investigating the use of computed tomography for the evaluation of therapeutic response in endobronchial tuberculosis.OBJECTIVE: A retrospective study was performed to evaluate the bronchoscopic and computed tomographic features of endobronchial tuberculosis before and after treatment. The aim of this study was to investigate the usefulness of computed tomography for the assessment of treatment.METHODS: The clinical, pathological and bronchoscopic features of endobronchial tuberculosis were evaluated in 55 patients. The age range of the patients was 21 to 52 years. Computed tomography and bronchoscopy were performed before and after treatment.RESULTS: Diagnosis of tuberculosis was confirmed by culture and histopathological examination. Bronchoscopic examination revealed 89 endobronchial lesions of various types in 55 patients. The exudative type was the most common. Follow-up bronchoscopy revealed that exudative-, ulcerative- and granular-type lesions healed completely. Computed tomography performed after treatment correlated well with the follow-up bronchoscopic findings.CONCLUSION: The results suggest that follow-up computed tomography is useful for the evaluation of therapeutic response and complications associated with endobronchial tuberculosis, and may replace bronchoscopy.

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Correlation of Biochemical Markers of Primary Hyperparathyroidism with Single Adenoma Weight and Volume

Indian Journal of Surgery ◽

10.1007/s12262-012-0428-5 ◽

2012 ◽

Vol 75 (2) ◽

pp. 102-105 ◽

Cited By ~ 6

Author(s):

F. Kamani ◽

A. Najafi ◽

S. S. Mohammadi ◽

S. Tavassoli ◽

S. P. Shojaei

Keyword(s):

Primary Hyperparathyroidism ◽

Biochemical Markers ◽

Single Adenoma

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Cryptococcal infections in children: retrospective study and review from Australia

Future Microbiology ◽

10.2217/fmb-2019-0215 ◽

2019 ◽

Vol 14 (18) ◽

pp. 1531-1544

Author(s):

Alice Grimshaw ◽

Pamela Palasanthiran ◽

Julie Huynh ◽

Ben Marais ◽

Sharon Chen ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Retrospective Study ◽

Acute Lymphoblastic Leukemia ◽

Literature Review ◽

Lymphoblastic Leukemia ◽

Central Nervous System Infection ◽

Significant Morbidity ◽

Neurological Sequelae ◽

Substantial Morbidity

Aim: Cryptococcosis causes significant morbidity and mortality worldwide, but pediatric data are limited. Methods: A retrospective literature review of Australian pediatric cryptococcosis and additional 10-year audit of cases from a large pediatric network. Results: 22 cases of cryptococcosis in children were identified via literature review: median age was 13.5 years (IQR 7.8–16 years), 18/22 (82%) had meningitis or central nervous system infection. Where outcome was reported, 11/18 (61%) died. Of six audit cases identified from 2008 to 2017, 5 (83%) had C. gattii disease and survived. One child with acute lymphoblastic leukemia and C. neoformans infection died. For survivors, persisting respiratory or neurological sequelae were reported in 4/6 cases (67%). Conclusion: Cryptococcosis is uncommon in Australian children, but is associated with substantial morbidity.

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Common Femoral Vein Aneurysm Simulating an Inguinal Hernia

The American Surgeon ◽

10.1177/000313480507100711 ◽

2005 ◽

Vol 71 (7) ◽

pp. 591-594 ◽

Cited By ~ 2

Author(s):

Eric T. Castaldo ◽

Eric H. Williams ◽

Jeffrey Dattilo ◽

Mark Passman ◽

Thomas Naslund ◽

...

Keyword(s):

Hernia Repair ◽

Femoral Vein ◽

Diagnostic Testing ◽

Operative Management ◽

Diagnostic Strategy ◽

Significant Morbidity ◽

Management Options ◽

Common Femoral Vein ◽

Surgical Exploration ◽

Elective Repair

Common femoral vein aneurysms are rare, yet knowledge of this entity is important for the surgeon who performs hernia repairs. This is because common femoral vein aneurysms can simulate inguinal or femoral hernias, and misdiagnosis can lead to significant morbidity if treated incorrectly. To our knowledge, only five other cases of femoral aneurysms simulating inguinal or femoral hernias have been reported. We present the case of a 50-year-old male with inguinal pain and swelling who was found to have a common femoral vein aneurysm at surgical exploration for hernia repair. The etiology, diagnostic strategy, and management options for common femoral vein aneurysm are presented and are followed by recommendations for operative management. In the case of an unanticipated femoral aneurysm found during hernia repair, we recommend termination of the procedure followed by elective repair to be performed after appropriate diagnostic testing has been completed.

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Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations

The Journal of Rheumatology ◽

10.3899/jrheum.160763 ◽

2017 ◽

Vol 44 (4) ◽

pp. 482-487 ◽

Cited By ~ 11

Author(s):

Kentaro Noda ◽

Ken Yoshida ◽

Taro Ukichi ◽

Kazuhiro Furuya ◽

Kenichiro Hirai ◽

...

Keyword(s):

Creatine Kinase ◽

Retrospective Study ◽

Interstitial Lung Disease ◽

Lung Disease ◽

Medical Records ◽

Histopathological Examination ◽

Newly Diagnosed ◽

Manual Muscle Test ◽

Clinical Variables ◽

The Relationship

Objective.To determine the association between fasciitis and the clinical variables in patients with dermatomyositis (DM) and polymyositis (PM).Methods.We retrospectively reviewed the medical records of 32 patients (24 DM, 8 PM) with newly diagnosed DM and PM and in whom fascia and muscle specimens were histopathologically examined. The relationship between fasciitis and the clinical variables was statistically analyzed. These included age, sex, myalgia, muscle weakness, creatine kinase (CK) and aldolase activities, anti-Jo1 antibody, interstitial lung disease, and malignancy.Results.Twenty (62.5%) of the 32 patients who underwent the histopathological examination of a fascia specimen had fasciitis, including 18 (75%) of 24 patients with DM and 2 (25%) of 8 patients with PM. The frequency of fasciitis was significantly higher among the patients with DM than among the patients with PM (p < 0.05). Histopathologically, fasciitis in PM was very mild in comparison to that in DM. The frequency of myalgia in patients with fasciitis was significantly higher than that in patients without fasciitis (p < 0.05). However, myalgia was not associated with myositis. There were no significant differences in the patients with and without fasciitis in age, sex, manual muscle test 8 scores, CK or aldolase activities, or the presence of anti-Jo1 antibodies and malignancy.Conclusion.The frequency of fasciitis was significantly higher among patients with DM than among those with PM. Fasciitis, rather than myositis, was associated with myalgia.

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