Knowledge, attitude and practices of oral rehydration therapy among mothers coming to tertiary care centre

Background: Diarrhoea is a major cause of morbidity and mortality among under-five children. Correct knowledge regarding oral rehydration therapy (ORT) helps prevent morbidity and mortality due to diarrhoea. The objective of this study is to assess the knowledge, attitude and practice of mothers of under-five children regarding ORT and home management of diarrhoea.Methods: Study period from December 1st, 2017 to December 31st, 2017, total of 200 mothers were enrolled in this study. The data was entered in Microsoft excel sheet and percentages were calculated.Results: 95% of mothers were aware about ORS. ORS was given by parents on own in16%, 55% were advised by doctor. Only 60% knew how to prepare ORS correctly. About 45.7% had used bottle to give ORS and 55.3% used cup and spoon. About 67.9% had knowledge of quantity of ORS to be given during diarrhoea episode. Exclusive breast feeding was practised in 86% of mothers till 6 months of age. Misconceptions about the use of ORS were seen in 60% and more among illiterates. About 21% mothers’ felt ORS should be stopped if diarrhoea continues. Only 5% of mothers felt ORS can be given even if child has vomiting. About 9% mothers felt no fluids should be given during diarrhoea.Conclusions: Mothers’ knowledge and attitude on use of ORS in diarrhoea need to be improved.

Efficacy of Diosmectite (Smecta)®in the Treatment of Acute Watery Diarrhoea in Adults: A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study

Background. Although diosmectite has demonstrated efficacy in the treatment of acute watery diarrhoea in children, its efficacy in adults still needs to be assessed. The objective of this study was therefore to assess the efficacy of diosmectite on the time to recovery in adults with acute diarrhoea.Methods. A total of 346 adults with at least three watery stools per day over a period of less than 48 hours were prospectively randomized to diosmectite (6 g tid) or placebo during four days. The primary endpoint was time to diarrhoea recovery.Results. In the intention-to-treat population, median time to recovery was 53.8 hours (range [3.7–167.3]) with diosmectite (n=166) versus 69.0 hours [2.2–165.2] with placebo, (n=163;P=.029), which corresponds to a difference of 15.2 hours. Diosmectite was well tolerated.Conclusion. Diosmectite at 6 g tid was well tolerated and reduced the time to recovery of acute watery diarrhoea episode in a clinically relevant manner.

Diarrhoea Morbidity Differentials among Children in Pakistan

The present study used the 1995-96 Pakistan Integrated Household Survey data to determine the socio-economic, demographic, and environmental covariates of both prevalence and duration of diarrhoea among children under five in Pakistan. Seven logit models were estimated to determine factors influencing the probability of occurrence of diarrhoea. Seven Proportional Hazards Models were used to examine factors determining the duration of diarrhoea. Results revealed that around 20 percent of children under five suffered from diarrhoea in the 30 days prior to the survey. Child’s age was negatively associated with diarrhoea morbidity. Children who had measles immunisation were less likely than children without this immunisation to have diarrhoea. The study also revealed that in controlling the occurrence of diarrhoea among children, sanitation facilities seemed to be more important than the supply of drinking-water. With respect to the duration of diarrhoea, the hazard models showed that younger children, particularly under the age of two, were relatively at a greater risk to suffer from longer diarrhoea episode. The use of Nimkol (ORT) showed a significant and positive effect on recovering quickly from the diarrhoea morbidity. The findings of the study suggest that mothers should be given health education so that they are familiar with the simply prepared treatment, Nimkol, and have knowledge about personal hygiene, and specially of preparing supplementary foods for children.