inchanggou lead-zinc mining area, Ningnan county, Sichuan province is a medium reserves ore deposit in recent years. In order to study origin of the deposit,lead and sulfur isotopic geochemical features of the deposit must be research. In the deposit,mean value of 206Pb/204Pb of 9 samples is 0.285 (from 18.116 to 18.401), mean value of 207Pb/204Pb is 0.098 (from 15.658 to 15.756),and mean value of 208Pb/204Pb is 0.635 (from 38.249 to 38.884).which show lead of the ore deposit come main from upper earth's crust and few from orogenic zone. Average value is δ34S in the lead-zinc ore is 15.02 per thousand(from 5.8 per thousand to 20.32 per thousand), with positive value of sulphur isotopic composition. It is shown as heavy sulfur-rich, which is similar with composition characteristics of δ34S of seawater evaporate. The deposit is a strata-bound deposit with multi-material source.