Faith in an invisible, intrusive spirit world necessarily shapes how early moderns understood the various and constant transactions between self and place. A Midsummer Night’s Dream not only stages the unseen spirit world for its audience, but it also suggests that the embodied minds of Demetrius, Bottom, and even Theseus have been unknowingly breached and altered by invisible spirituous entities. Cognition and affect in A Midsummer Night’s Dream prove to be ecological. However, our understanding of how early moderns perceived this ecology should encompass their belief in indiscernible, nonhuman agents. As scholars have observed, the distribution of cognitive and affective processes across brain, body, and world extends the human mind into the environment. A Midsummer Night’s Dream helps us see how early moderns also discerned this process in reverse, where an animated, and surprisingly motivated, spirit world extends through brains and bodies.