This chapter shows that, across languages, indefinites show a tendency to become increasingly restricted to ever-stronger negative polarity contexts, eventually becoming restricted to the scope of negation and beginning to enter negative-concord relations. It is shown that developments affecting indefinites can be grouped into two types of development: a quantifier cycle and a free-choice cycle. In the former, indefinites gradually change from (more) positive to (more) negative, in the latter, original free-choice indefinites become NPI-indefinites. It is also shown that negative quantifiers do not typically arise through either development, but through univerbation with a former negative particle. Apparently countercyclic developments can be observed as well. The chapter concludes with an overview of the typology of negative concord, and the diachronic connections between the types of negative concord.