Rational Drug Design
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17

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Published By Humana Press

9781627030076, 9781627030083

Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

Mouse Models for Tumor Metastasis

Rational Drug Design ◽

10.1007/978-1-62703-008-3_17 ◽

2012 ◽

pp. 221-228 ◽

Author(s):

Shengyu Yang ◽

J. Jillian Zhang ◽

Xin-Yun Huang

Keyword(s):

Mouse Models ◽

Tumor Metastasis

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Using a Modified Yeast Two-Hybrid System to Screen for Chemical GEF Inhibitors

Rational Drug Design ◽

10.1007/978-1-62703-008-3_7 ◽

2012 ◽

pp. 81-95 ◽

Author(s):

Anne Blangy ◽

Philippe Fort

Keyword(s):

Hybrid System ◽

Yeast Two Hybrid ◽

Yeast Two Hybrid System ◽

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Random Mutagenesis of Peptide Aptamers as an Optimization Strategy for Inhibitor Screening

Rational Drug Design ◽

10.1007/978-1-62703-008-3_8 ◽

2012 ◽

pp. 97-118 ◽

Author(s):

Nathalie Bouquier ◽

Sylvie Fromont ◽

Anne Debant ◽

Susanne Schmidt

Keyword(s):

Random Mutagenesis ◽

Optimization Strategy ◽

Peptide Aptamers ◽

Inhibitor Screening

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Identification of Allosteric Inhibitors of p21-Activated Kinase

Rational Drug Design ◽

10.1007/978-1-62703-008-3_6 ◽

2012 ◽

pp. 67-79

Author(s):

Julien Viaud ◽

Jeffrey R. Peterson

Keyword(s):

Allosteric Inhibitors ◽

P21 Activated Kinase

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An In Vitro Screening to Identify Drug-Resistant Mutations for Target-Directed Chemotherapeutic Agents

Rational Drug Design ◽

10.1007/978-1-62703-008-3_14 ◽

2012 ◽

pp. 175-184

Author(s):

Mohammad Azam

Keyword(s):

Chemotherapeutic Agents ◽

Drug Resistant ◽

In Vitro Screening

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On Setting Up and Assessing Docking Simulations for Virtual Screening

Rational Drug Design ◽

10.1007/978-1-62703-008-3_1 ◽

2012 ◽

pp. 1-16

Author(s):

Jacek Biesiada ◽

Aleksey Porollo ◽

Jaroslaw Meller

Keyword(s):

Virtual Screening ◽

Docking Simulations

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Affinity Purification of Protein Kinases that Adopt a Specific Inactive Conformation

Rational Drug Design ◽

10.1007/978-1-62703-008-3_11 ◽

2012 ◽

pp. 143-151

Author(s):

Pratistha Ranjitkar ◽

Dustin J. Maly

Keyword(s):

Protein Kinases ◽

Affinity Purification ◽

Inactive Conformation

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Determination of the Kinetics and Thermodynamics of Ligand Binding to a Specific Inactive Conformation in Protein Kinases

Rational Drug Design ◽

10.1007/978-1-62703-008-3_12 ◽

2012 ◽

pp. 153-159

Author(s):

Sanjay B. Hari ◽

Pratistha Ranjitkar ◽

Dustin J. Maly

Keyword(s):

Ligand Binding ◽

Protein Kinases ◽

Kinetics And Thermodynamics ◽

Inactive Conformation

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Use of a Fluorescent ATP Analog to Probe the Allosteric Conformational Change in the Active Site of the Protein Kinase PDK1

Rational Drug Design ◽

10.1007/978-1-62703-008-3_10 ◽

2012 ◽

pp. 133-141

Author(s):

Valerie Hindie ◽

Laura A. Lopez-Garcia ◽

Ricardo M. Biondi

Keyword(s):

Protein Kinase ◽

Conformational Change ◽

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Virtual Ligand Screening Combined with NMR to Identify Dvl PDZ Domain Inhibitors Targeting the Wnt Signaling

Rational Drug Design ◽

10.1007/978-1-62703-008-3_2 ◽

2012 ◽

pp. 17-28

Author(s):

Jufang Shan ◽

Jie J. Zheng

Keyword(s):

Wnt Signaling ◽

Ligand Screening ◽

Virtual Ligand Screening

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