Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery
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Published By Springer New York

9781493929139, 9781493929146

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Nuts and Bolts of CF3 and CH3 NMR Toward the Understanding of Conformational Exchange of GPCRs

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_4 ◽

2015 ◽

pp. 39-51 ◽

Cited By ~ 4

Author(s):

R. Scott Prosser ◽

Tae Hun Kim

Keyword(s):

Conformational Exchange

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High-Throughput Screening for Allosteric Modulators of GPCRs

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_15 ◽

2015 ◽

pp. 223-240 ◽

Cited By ~ 10

Author(s):

Robert L. Bertekap ◽

Neil T. Burford ◽

Zhuyin Li ◽

Andrew Alt

Keyword(s):

High Throughput ◽

High Throughput Screening ◽

Allosteric Modulators

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The Dynamic Process of Drug–GPCR Binding at Either Orthosteric or Allosteric Sites Evaluated by Metadynamics

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_18 ◽

2015 ◽

pp. 277-294 ◽

Cited By ~ 15

Author(s):

Sebastian Schneider ◽

Davide Provasi ◽

Marta Filizola

Keyword(s):

Dynamic Process ◽

Allosteric Sites

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Virus-Mediated Expression of DREADDs for In Vivo Metabolic Studies

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_14 ◽

2015 ◽

pp. 205-221 ◽

Cited By ~ 2

Author(s):

Mario Rossi ◽

Zhenzhong Cui ◽

Ken-ichiro Nakajima ◽

Jianxin Hu ◽

Lu Zhu ◽

...

Keyword(s):

Metabolic Studies

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Bioluminescence Resonance Energy Transfer Approaches to Discover Bias in GPCR Signaling

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_13 ◽

2015 ◽

pp. 191-204 ◽

Cited By ~ 2

Author(s):

Elizabeth K. M. Johnstone ◽

Kevin D. G. Pfleger

Keyword(s):

Energy Transfer ◽

Resonance Energy Transfer ◽

Resonance Energy ◽

Bioluminescence Resonance Energy Transfer ◽

Gpcr Signaling

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Approaches to Assess Functional Selectivity in GPCRs: Evaluating G Protein Signaling in an Endogenous Environment

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_12 ◽

2015 ◽

pp. 177-189 ◽

Cited By ~ 8

Author(s):

Laura M. Bohn ◽

Lei Zhou ◽

Jo-Hao Ho

Keyword(s):

G Protein ◽

G Protein Signaling ◽

Protein Signaling ◽

Functional Selectivity

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Monitoring G Protein Activation in Cells with BRET

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_8 ◽

2015 ◽

pp. 107-113 ◽

Cited By ~ 25

Author(s):

Ikuo Masuho ◽

Kirill A. Martemyanov ◽

Nevin A. Lambert

Keyword(s):

G Protein ◽

Protein Activation ◽

G Protein Activation ◽

In Cells

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Docking and Virtual Screening Strategies for GPCR Drug Discovery

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_17 ◽

2015 ◽

pp. 251-276 ◽

Cited By ~ 13

Author(s):

Thijs Beuming ◽

Bart Lenselink ◽

Daniele Pala ◽

Fiona McRobb ◽

Matt Repasky ◽

...

Keyword(s):

Drug Discovery ◽

Virtual Screening ◽

Screening Strategies

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Purification of Stabilized GPCRs for Structural and Biophysical Analyses

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_1 ◽

2015 ◽

pp. 1-15 ◽

Cited By ~ 8

Author(s):

James C. Errey ◽

Andrew S. Doré ◽

Andrei Zhukov ◽

Fiona H. Marshall ◽

Robert M. Cooke

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Single-Molecule Fluorescence Microscopy for the Analysis of Fast Receptor Dynamics

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery ◽

10.1007/978-1-4939-2914-6_5 ◽

2015 ◽

pp. 53-66 ◽

Cited By ~ 1

Author(s):

Julia Wagner ◽

Titiwat Sungkaworn ◽

Katrin G. Heinze ◽

Martin J. Lohse ◽

Davide Calebiro

Keyword(s):

Fluorescence Microscopy ◽

Single Molecule ◽

Single Molecule Fluorescence ◽

Receptor Dynamics ◽

Single Molecule Fluorescence Microscopy

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Methods in Molecular Biology - G Protein-Coupled Receptors in Drug DiscoveryLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer New York

Nuts and Bolts of CF3 and CH3 NMR Toward the Understanding of Conformational Exchange of GPCRs

High-Throughput Screening for Allosteric Modulators of GPCRs

The Dynamic Process of Drug–GPCR Binding at Either Orthosteric or Allosteric Sites Evaluated by Metadynamics

Virus-Mediated Expression of DREADDs for In Vivo Metabolic Studies

Bioluminescence Resonance Energy Transfer Approaches to Discover Bias in GPCR Signaling

Approaches to Assess Functional Selectivity in GPCRs: Evaluating G Protein Signaling in an Endogenous Environment

Monitoring G Protein Activation in Cells with BRET

Docking and Virtual Screening Strategies for GPCR Drug Discovery

Purification of Stabilized GPCRs for Structural and Biophysical Analyses

Single-Molecule Fluorescence Microscopy for the Analysis of Fast Receptor Dynamics

Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Discovery
Latest Publications