This chapter examines the imperial and Indigenous territorialities that defined the Río de la Plata before the invention of a Luso-Hispanic border. It demonstrates that itinerant Native communities (tolderías) were the principal arbiters of access to and travel across the countryside, where feral livestock roamed. Strings of Spanish, Portuguese, and Jesuit-Guarani settlements, rather than constituting conterminous frontiers or provincial units, were relatively isolated points along fragile corridors or waterways, restricted to the perimeter of the region by neighboring tolderías. Tolderías competed with one another and used colonial settlements for trade or as sites of temporary refuge in moments of duress. In the absence of any singular authority, territorial order governed power relations between settlers and tolderías, and tilted in tolderías’ favor.