Skin Changes Secondary to Hydroxyurea Therapy

1975 ◽  
Vol 111 (2) ◽  
pp. 183 ◽  
Author(s):  
B. J. Kennedy
Keyword(s):  
Skin Changes ◽  
Hydroxyurea Therapy

Skin changes secondary to hydroxyurea therapy

1975 ◽  
Vol 111 (2) ◽  
pp. 183-187 ◽  
Author(s):  
B. J. Kennedy
Keyword(s):  
Skin Changes ◽  
Hydroxyurea Therapy

Skin Changes Help Identify Scleroderma Mimics

2009 ◽  
Vol 40 (7) ◽  
pp. 37
Author(s):  
PATRICE WENDLING
Keyword(s):  
Skin Changes

Cutaneous ulcers following hydroxyurea therapy

Phlebologie ◽  
2004 ◽  
Vol 33 (06) ◽  
pp. 202-205 ◽  
Author(s):  
K. Hartmann ◽  
S. Nagel ◽  
T. Erichsen ◽  
E. Rabe ◽  
K. H. Grips ◽  
...  
Keyword(s):  
Side Effects ◽  
Side Effect ◽  
Antineoplastic Agent ◽  
Limited Time ◽  
Myeloproliferative Diseases ◽  
Dermatological Side Effects ◽  
Chronic Myeloproliferative Diseases ◽  
Hydroxyurea Therapy

SummaryHydroxyurea (HU) is usually a well tolerated antineoplastic agent and is commonly used in the treatment of chronic myeloproliferative diseases. Dermatological side effects are frequently seen in patients receiving longterm HU therapy. Cutaneous ulcers have been reported occasionally.We report on four patients with cutaneous ulcers whilst on long-term hydroxyurea therapy for myeloproliferative diseases. In all patients we were able to reduce the dose, or stop HU altogether and their ulcers markedly improved. Our observations suggest that cutaneous ulcers should be considered as possible side effect of long-term HU therapy and healing of the ulcers can be achieved not only by cessation of the HU treatment, but also by reducing the dose of hydroxyurea for a limited time.

Repeated Occurrence of Skin Necrosis Twice Following Coumarin Intake and Subsequently During Decrease of Vitamin K Dependent Coagulation Factors Associated with Cholestasis

1982 ◽  
Vol 48 (03) ◽  
pp. 245-246 ◽  
Author(s):  
V Hofmann ◽  
P G Frick
Keyword(s):  
Skin Necrosis ◽  
Oral Anticoagulants ◽  
Subcutaneous Fat ◽  
Coagulation Factors ◽  
Fat Necrosis ◽  
Subcutaneous Fat Necrosis ◽  
Skin Changes ◽  
Factors Associated ◽  
Therapeutic Anticoagulation ◽  
Coumarin Necrosis

SummaryA female patient is described who developed skin and subcutaneous fat necrosis on two occasions after intake of acenocoumarol.Several months later identical skin changes occurred during an episode of cholestasis associated with a prolongation of the prothrombin time to an extent comparable with therapeutic anticoagulation; intake of oral anticoagulants could be excluded.This association gives new insights in the pathogenetic mechanisms responsible for the so-called coumarin necrosis and indicates that it may be not due to drug toxicity or allergy.

Neonatal Nasal Tip Necrosis Secondary to Suspected In Utero Pressure/Positioning

FACE ◽  
2021 ◽  
pp. 273250162110342
Author(s):  
Megan J. Natali ◽  
Madeleine K. Bruce ◽  
Miles J. Pfaff ◽  
Jesse A. Goldstein
Keyword(s):  
Head And Neck ◽  
Vaginal Delivery ◽  
Conservative Management ◽  
Rare Event ◽  
In Utero ◽  
Birth Trauma ◽  
Neck Injury ◽  
Skin Changes ◽  
Nasal Tip ◽  
Head And Neck Injury

Head and neck injury as a consequence of in utero pressure and birth trauma is a rare event. We report a case of a patient who was born full-term via vaginal delivery and presented soon after birth with skin changes over the nasal tip consistent with a pressure-related injury that progressed to a stable eschar. Conservative management with close clinical monitoring resulted in a well-healed wound over the nasal tip. A detailed discussion regarding the diagnosis and management of head and neck lesions after birth is provided.

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