Antimicrobial management of Helicobacter pylori-associated gastrointestinal tract disease

Abstract Background Non neoplastic GI lesions in pediatrics are variable and differ in types and prevalence among each pediatric age group. Helicobacter pylori is an important pathogen that can cause gastritis and peptic ulcers in adults as well as in children. Celiac disease is a gluten-dependent autoimmune disorder which affects individuals having genetic susceptibility. Eosinophilic gastrointestinal diseases are disorders that primarily affect the gastrointestinal tract with eosinophil-rich inflammation in the absence of known causes for eosinophilia. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. It seems that it is one of the most common gastrointestinal diseases affecting children in the developed countries. Aim of the work To study different types of paediatric non neoplastic gastrointestinal lesions from gastrointestinal endoscopic biopsies received at the Pathology Department in Ain Shams University hospital during a period of 2 years (2017-2018), and to correlate them with the clinicopathological presentations and endoscopic findings. Patients and Methods A cross sectional study was conducted on all pediatric gastrointestinal biopsies received at Pathology Department in Ain Shams University Hospital during the period of two years (2017- 2018). Only cases with information for all the covariates (n = 580) were selected and the results were statistically analyzed. Results Total 580 pediatric cases were enrolled according to inclusion criteria. Nonspecific gastrointestinal inflammation represented (47.1%), Helicobacter pylori associated gastrointestinal inflammation represented (43.5%), Eosinophilic gastrointestinal disease represented (3.8%), Inflammatory bowel disease (IBD) represented (3.7%), Celiac disease represented (1.9%). Conclusion This is the first study conducted in Ain Shams University Hospitals to assess the different types of pediatric non neoplastic gastrointestinal lesions received with clinicopathological and endoscopic correlation. The most common pediatric non neoplastic GI lesion is Helicobacter pylori infection. The diagnosis of pediatric non neoplastic GI disorder necessitates interdepartmental teamwork between GI pediatricians and pathologists.

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Infectious disorders of the upper gastrointestinal tract (excluding Helicobacter pylori )

Diagnostic Histopathology ◽

10.1016/j.mpdhp.2008.07.003 ◽

2008 ◽

Vol 14 (9) ◽

pp. 427-436 ◽

Cited By ~ 8

Author(s):

Laura W. Lamps

Keyword(s):

Helicobacter Pylori ◽

Gastrointestinal Tract ◽

Upper Gastrointestinal Tract ◽

Upper Gastrointestinal

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The Application Effect of High Quality Nursing Service in the Painless Gastroscopy Examination

Journal of Nursing ◽

10.18686/jn.v2i1.2 ◽

2013 ◽

Vol 2 ◽

pp. 6

Author(s):

Jina Guo

Keyword(s):

Blood Pressure ◽

Gastrointestinal Tract ◽

Reaction Rate ◽

Adverse Reactions ◽

High Quality ◽

Nursing Service ◽

Satisfaction Rate ◽

Low Blood Pressure ◽

Tract Disease ◽

Hands And Feet

Objective: To discuss the application effect of high quality nursing service in the painless gastroscopy examination. Methods: Selected 132 cases of patients with gastrointestinal tract disease admitted by my hospital from May 2012 to May 2013 as the research object, 132 cases of patients with gastrointestinal tract disease were all given painless gastroscopy examination, clinically, all of them were given high quality nursing service. Observed and recorded nursing effect. Results: Among 132 cases of patients, there were 3 cases appeared untoward effect such as choking cough, respiratory depression, abdominal pain, low blood pressure and other adverse reactions, the adverse reaction rate was 2.27% (3/132); 0 cases of hospital infection; 132 cases all had side effects of propofol (dizzy giddy, hands and feet became limp, but no case of fell down; 131 patients were satisfied with high quality nursing service, the satisfaction rate was 99.2% (131/132). Conclusion: The application effect of high quality nursing service in painless gastroscopy examination was remarkable.

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