scholarly journals Mandibular Segmental Defect Regenerated With Macroporous Biphasic Calcium Phosphate, Collagen Membrane, and Bone Marrow Graft in Dogs

2010 ◽  
Vol 136 (10) ◽  
pp. 971 ◽  
Author(s):  
Franck Jégoux ◽  
Eric Goyenvalle ◽  
Ronan Cognet ◽  
Olivier Malard ◽  
Françoise Moreau ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Calcium Phosphate ◽  
Biphasic Calcium Phosphate ◽  
Collagen Membrane ◽  
Segmental Defect ◽  
Marrow Graft ◽  
Bone Marrow Graft

Repairing Segmental Defect with a Composite Associating Collagen Membrane and MBCP® Combined with Total Bone Marrow Graft in Irradiated Bone Defect: an Experimental Study in Rabbit

2007 ◽  
Vol 361-363 ◽  
pp. 1245-1248 ◽  
Author(s):  
Franck Jegoux ◽  
Eric Aguado ◽  
Ronan Cognet ◽  
Oliver Malard ◽  
Françoise Moreau ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Ingrowth ◽  
Weight Bearing ◽  
Autologous Bone Marrow ◽  
Collagen Membrane ◽  
Segmental Defect ◽  
Marrow Graft ◽  
Bone Marrow Graft ◽  
Total Bone Marrow

The aim of this study was to study bone marrow quality from various location and species for reconstruction of segmental critical size defect in irradiated weigh bearing bone. Sample of bone marrow aspirates from rabbits and Beagle dog were analyzed. Rabbits were implanted with a composite associating resorbable collagen membrane plus micro macroporous biphasic calcium phosphate (MBCP®) and autologous bone marrow (BM) injected after irradiation. Bone marrow samples were found to be significantly less rich in tibia than in humerus and ilium in Dog and less rich in Dog than in Rabbit (p<0,05). Successful osseous colonization bridging of the defect were obtain at 16 weeks in all animals. Identical repartition of bone ingrowth and residual ceramic at the different levels of the implant suggest an osteoinduction role of the bone marrow graft in the center of the defect. This model succeeded in reconstruct a large segmental defect in weight bearing and irradiated bone in rabbit.

PRETRANSPLANT LYMPHOCYTOTOXINS AND BONE-MARROW GRAFT REJECTION

The Lancet ◽  
1978 ◽  
Vol 311 (8057) ◽  
pp. 170-172 ◽  
Author(s):  
R.P. Gale ◽  
M. Cahan ◽  
J.H. Fitchen ◽  
G. Opelz ◽  
M.J. Cline
Keyword(s):  
Bone Marrow ◽  
Graft Rejection ◽  
Marrow Graft ◽  
Bone Marrow Graft

Influence of bone marrow graft lymphocyte subsets on outcome after HLA-identical sibling transplants

2001 ◽  
Vol 29 (11) ◽  
pp. 1347-1352 ◽  
Author(s):  
Vanderson Rocha ◽  
Marie-Vonique Carmagnat ◽  
Sylvie Chevret ◽  
Odile Flinois ◽  
Henrique Bittencourt ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Lymphocyte Subsets ◽  
Marrow Graft ◽  
Bone Marrow Graft

scholarly journals CFU-GM content of bone marrow graft correlates with time to hematologic reconstitution following autologous bone marrow transplantation with 4- hydroperoxycyclophosphamide-purged bone marrow

Blood ◽  
1987 ◽  
Vol 70 (1) ◽  
pp. 271-275
Author(s):  
SD Rowley ◽  
M Zuehlsdorf ◽  
HG Braine ◽  
OM Colvin ◽  
J Davis ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Peripheral Blood ◽  
Autologous Bone Marrow Transplantation ◽  
Autologous Bone Marrow ◽  
Marrow Graft ◽  
Blood Leukocytes ◽  
Cell Content ◽  
Hematopoietic Stem ◽  
Bone Marrow Graft ◽  
Autologous Bone

Autologous bone marrow transplants (BMTs) can repopulate the hematologic system of patients treated with marrow-ablative chemotherapy and/or radiotherapy. However, treatment of the bone marrow graft to eliminate residual tumor cells prior to reinfusion can delay the return of peripheral blood elements, presumably from damage to or loss of hematopoietic stem cells responsible for hematologic recovery. To develop a model predictive of hematologic recovery, we studied the progenitor cell contents of 4-hydroperoxycyclophosphamide (100 micrograms/mL)-purged bone marrow grafts of 40 consecutive patients undergoing autologous BMT at this center. Granulocyte-macrophage colonies (CFU-GM) were grown from all grafts after treatment with this chemotherapeutic agent, but erythroid (BFU-E) and mixed (CFU-GEMM) colonies were grown from only 44% and 33% of the grafts respectively. The recovery of CFU-GM after purging ranged from 0.07% to 23%. The logarithm of CFU-GM content of the treated grafts was linearly correlated with the time to recovery of peripheral blood leukocytes (r = -0.80), neutrophils (r = -0.79), reticulocytes (r = -0.60), and platelets (r = -0.66). The CFU-GM content of purged autologous bone marrow grafts may reflect the hematopoietic stem cell content of the grafts and thus predict the rate of hematologic recovery in patients undergoing autologous BMT.

scholarly journals Uncomplicated HL-A Matched Sibling Bone Marrow Graft for Combined Immune Deficiency

BMJ ◽  
1972 ◽  
Vol 2 (5808) ◽  
pp. 265-269 ◽  
Author(s):  
M. Yamamura ◽  
R. C. F. Newton ◽  
D. C. O. James ◽  
J. G. Humble ◽  
L. J. Butler ◽  
...  
Keyword(s):  
Immune Deficiency ◽  
Bone Marrow ◽  
Marrow Graft ◽  
Bone Marrow Graft ◽  
Matched Sibling ◽  
Combined Immune Deficiency
Sign in / Sign up

Export Citation Format

Share Document