Distraction Osteogenesis of Severely Resorbed Mandible

Edentulous patients require an adequate rehabilitation so that the alveolar ridge in the interforaminal region be restored for subsequent implant-supported overdentures. The ultimate goal of distraction is to reconstruct the alveolar ridge to a suitable height and width compatible with Atwood class 2 in an appropriate direction allowing the sagittal interalveolar relation to be normally restored. Methods. A 65-year-old man presented with a grade 4 Mandibular atrophy as per Atwood classification which resulted in unsatisfactory treatment with full dentures. Endo-Distractor Krenkel® device was used for anterior mandibular vertical distraction osteogenesis. Four mandibular implants (ITI Straumann, Basel, Switzerland) measuring diameter Ø = 4.1 mm and length L = 16 mm were inserted after the required retention period. Standardized prosthetic treatment was completed with titanium bar retained over dentures. Results. A distraction of 11 mm was achieved within 18 days followed by a retention period of 4 months. No signs of infection nor distractor anchorage loosening were detected, and minimal lingual tilting has occurred. Conclusion. Distraction is possible on severely atrophic mandibles. The quality of bone reconstruction is satisfactory for both functional and esthetic results.

In Vivo Study of Nasal Bone Reconstruction with Collagen, Elastin and Chitosan Membranes in Abstainer and Alcoholic Rats

The aim of the present study was to evaluate the use of collagen, elastin, or chitosan biomaterial for bone reconstruction in rats submitted or not to experimental alcoholism. Wistar male rats were divided into eight groups, submitted to chronic alcohol ingestion (G5 to G8) or not (G1 to G4). Nasal bone defects were filled with clot in animals of G1 and G5 and with collagen, elastin, and chitosan grafts in G2/G6, G3/G7, and G4/G8, respectively. Six weeks after, all specimens underwent radiographic, tomographic, and microscopic evaluations. Bone mineral density was lower in the defect area in alcoholic animals compared to the abstainer animals. Bone neoformation was greater in the abstainer groups receiving the elastin membrane and in abstainer and alcoholic rats receiving the chitosan membrane (15.78 ± 1.19, 27.81 ± 0.91, 47.29 ± 0.97, 42.69 ± 1.52, 13.81 ± 1.60, 18.59 ± 1.37, 16.54 ± 0.89, and 37.06 ± 1.17 in G1 to G8, respectively). In conclusion, osteogenesis and bone density were more expressive after the application of the elastin matrix in abstainer animals and of the chitosan matrix in both abstainer and alcoholic animals. Chronic alcohol ingestion resulted in lower bone formation and greater formation of fibrous connective tissue.

A Narrative Review of u-HA/PLLA, a Bioactive Resorbable Reconstruction Material: Applications in Oral and Maxillofacial Surgery

The advent of bioresorbable materials to overcome limitations and replace traditional bone-reconstruction titanium-plate systems for bone fixation, thus achieving greater efficiency and safety in medical and dental applications, has ushered in a new era in biomaterial development. Because of its bioactive osteoconductive ability and biocompatibility, the forged composite of uncalcined/unsintered hydroxyapatite and poly L-lactic acid (u-HA/PLLA) has attracted considerable interest from researchers in bone tissue engineering, as well as from clinicians, particularly for applications in maxillofacial reconstructive surgery. Thus, various in vitro studies, in vivo studies, and clinical trials have been conducted to investigate the feasibility and weaknesses of this biomaterial in oral and maxillofacial surgery. Various technical improvements have been proposed to optimize its advantages and limit its disadvantages. This narrative review presents an up-to-date, comprehensive review of u-HA/PLLA, a bioactive osteoconductive and bioresorbable bone-reconstruction and -fixation material, in the context of oral and maxillofacial surgery, notably maxillofacial trauma, orthognathic surgery, and maxillofacial reconstruction. It simultaneously introduces new trends in the development of bioresorbable materials that could used in this field. Various studies have shown the superiority of u-HA/PLLA, a third-generation bioresorbable biomaterial with high mechanical strength, biocompatibility, and bioactive osteoconductivity, compared to other bioresorbable materials. Future developments may focus on controlling its bioactivity and biodegradation rate and enhancing its mechanical strength.

Dental Anthropology-A Revolutionary Tool in Forensic Science

Dental anthropology is a field of physical anthropology that studies the origin, development, and evolution of anthropoid dentitions, as well as their relationship to social, physical, and cultural factors. Teeth have their own distinct morphology and physiology, which is in stark contrast to the body's genetic structure. Teeth are also unique among the resistant elements of archaeological and fossil remains in that they have been exposed on the body's surface throughout their lives. As a result, dental anthropology may be assessed in the mouth cavity of living humans using similar methods to those used for prehistoric relics. As a result, it's no surprise that practising dental surgeons have historically ranked well among dental anthropologists. This review’s initial purpose is to provide an overview of the morphological and non-morphological properties of animate dentitions that aid in the indirect identification of prehistoric remains and the understanding of their cultural, social, and physical relationships, as well as to assist forensic odontologists with craniofacial identification and skull bone reconstruction.

Possible Treatment of Severe Bone Dehiscences Based on 3D Bone Reconstruction—A Description of Treatment Methodology

Gingival recessions constitute serious limitations for effective interdisciplinary periodontal, orthodontic, and implant therapy. A proper bone morphology of the alveolar bone and soft tissues that cover it are interdependent. The regeneration procedures known to date are based on the use of autogenous bone, or its allogeneic, xenogeneic, or alloplastic substitutes. These substitutes are characterized by different osteogenesis potentials. No effective procedure for three-dimensional bone reconstruction for cases in which there is dentition with recessions has been described to date, especially in its vertical dimension. This article presents the patented method of the three-dimensional bone reconstruction of the anterior mandible with preserved dentition when using an allogeneic bone block, and also includes a case report with a 2-year follow-up as an example. Based on clinical observations, it was stated that the intended therapeutic effect was achieved. There was no recession, shallowing of the vestibule, signs of inflammation, or pathological mobility of the teeth in the area undergoing reconstruction. The radiographic images revealed the formation of a new layer of cortical bone on the vestibular side and a certain volume of cancellous bone. No radiological demarcation zone of brightening, which indicates an incomplete adaptation, integration, and reconstruction of the bone block, was found.

The general condition of patients requiring the alveolar bone crest reconstruction

Objectives: To present the survey questionnaire used for the medical assessment of patients requiring alveolar ridge reconstruction as well as the study of concomitant pathologies and their influence on the healing process. Material and methods: The study involved 173 patients aged between 18 and 69 years. All patients have been assessed according to the survey questionnaire developed to determine the patient’s general condition, life anamnesis, and medical history. Results: Out of the total of 173 patients, 72 (41.6%) had no concomitant pathologies, 8 patients (4.6%) had concomitant pathologies that did not interfere with the operation, 40 (23.1%) had pathologies that might affect the outcome of alveolar ridge reconstruction but still were admitted to surgery, and 53 patients (30.6%) had pathologies that could affect the outcome of the reconstruction procedure and were not admitted to bone grafting. Conclusions: Assessment of patients with alveolar ridge defects during preparation and planning of preimplantation bone reconstruction identified a number of concomitant pathologies, more or less noticed by the patient, which may remain unclear due to superficial study of the patient’s condition that is able to influence the surgical treatment outcome. These issues can be both intraoperative and postoperative and lead to failure of surgical treatment and further reoperation.