Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes

JAMA ◽  
1995 ◽  
Vol 273 (1) ◽  
pp. 59-65 ◽  
Author(s):  
I. B. Wilson
2015 ◽  
Vol 31 (9) ◽  
pp. 1871-1880 ◽  
Author(s):  
Camila Mello dos Santos ◽  
Roger Keller Celeste ◽  
Juliana Balbinot Hilgert ◽  
Fernando Neves Hugo

The aim of this study was to test Wilson & Cleary’s conceptual model of the direct and mediated pathways between clinical and non-clinical variables in relation to oral health-related quality of life. A random sample of 578 older people was evaluated. Wilson & Cleary’s conceptual model was tested using structural equations modeling including: biological variables, symptom status, functional health, oral health perceptions, oral health-related quality of life. Oral health-related quality of life was assessed with the Oral Health Impact Profile-14 (OHIP-14). In the final model, edentulism was negatively correlated to dissatisfaction of appearance of their dental prostheses (r = -0.25). Worse functional status was correlated with poor oral health perception (r = 0.24). Being aged over 68 (r = 0.25), being a female (r = 0.39) and living in rural areas (r = 0.15) had a direct effect on the edentulism. Age had a direct effect on OHIP-14 (r = -0.15). There was an indirect effect of sex on OHIP-14 via functional status (r = 0.12). The present findings partially support Wilson & Cleary’s model framework.


2020 ◽  
Vol 6 (1) ◽  
pp. 205521731984846
Author(s):  
Natali Farran ◽  
Batoul R Safieddine ◽  
Mariam Bayram ◽  
Tracy Abi Hanna ◽  
Joelle Massouh ◽  
...  

Background In the Middle East and North Africa (MENA) region, few studies explored the quality of life of multiple sclerosis patients and the factors affecting it. Objective The objective of this study was to explore studies on multiple sclerosis quality of life in the MENA area through a comprehensive literature review. To validate the Multiple sclerosis international Quality of Life (MusiQoL) and Modified Fatigue Impact Scale (MFIS) in Arabic, and investigate the impact of sociodemographic and clinical variables of Lebanese multiple sclerosis patients on quality of life. Methods As part of an ongoing observational prospective research study, data from 663 stable multiple sclerosis patients were analysed. Results In Lebanese multiple sclerosis patients, the Arabic MusiQoL and MFIS seem to be accurate and valid tools with high reliability coefficients and confirmatory factor analytic indices. Variables such as age and disease type predicted multiple sclerosis quality of life, yet were significantly affected by psychosocial fatigue. The influence of sociodemographic and clinical variables on quality of life dimensions varied. Being a woman with multiple sclerosis, receiving medications and experiencing physical fatigue worsens the psychological wellbeing quality of life dimension. Conclusion Several sociodemographic and clinical variables predicted the health-related quality of life dimensions of multiple sclerosis patients in MENA. Further in-depth investigation to guide more targeted clinical management is recommended. We encourage using validated multidimensional tools to measure quality of life in MENA such as the Arabic MusiQoL.


2015 ◽  
Vol 96 (1) ◽  
pp. 105-113 ◽  
Author(s):  
Noelle E. Carlozzi ◽  
Anna L. Kratz ◽  
Angelle M. Sander ◽  
Nancy D. Chiaravalloti ◽  
Tracey A. Brickell ◽  
...  

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