scholarly journals Association of Prenatal Maternal Psychological Distress With Fetal Brain Growth, Metabolism, and Cortical Maturation

2020 ◽  
Vol 3 (1) ◽  
pp. e1919940 ◽  
Author(s):  
Yao Wu ◽  
Yuan-Chiao Lu ◽  
Marni Jacobs ◽  
Subechhya Pradhan ◽  
Kushal Kapse ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Fetal Brain ◽  
Brain Growth ◽  
Maternal Psychological Distress ◽  
Growth Metabolism ◽  
Cortical Maturation

scholarly journals Neuroplacentology in congenital heart disease: placental connections to neurodevelopmental outcomes

2021 ◽  
Author(s):  
Rachel L. Leon ◽  
Imran N. Mir ◽  
Christina L. Herrera ◽  
Kavita Sharma ◽  
Catherine Y. Spong ◽  
...  
Keyword(s):  
Brain Development ◽  
Congenital Heart ◽  
Fetal Brain ◽  
In Utero ◽  
Structure And Function ◽  
Brain Growth ◽  
Neurodevelopmental Outcomes ◽  
Fetal Brain Development ◽  
And Function

Abstract Children with congenital heart disease (CHD) are living longer due to effective medical and surgical management. However, the majority have neurodevelopmental delays or disorders. The role of the placenta in fetal brain development is unclear and is the focus of an emerging field known as neuroplacentology. In this review, we summarize neurodevelopmental outcomes in CHD and their brain imaging correlates both in utero and postnatally. We review differences in the structure and function of the placenta in pregnancies complicated by fetal CHD and introduce the concept of a placental inefficiency phenotype that occurs in severe forms of fetal CHD, characterized by a myriad of pathologies. We propose that in CHD placental dysfunction contributes to decreased fetal cerebral oxygen delivery resulting in poor brain growth, brain abnormalities, and impaired neurodevelopment. We conclude the review with key areas for future research in neuroplacentology in the fetal CHD population, including (1) differences in structure and function of the CHD placenta, (2) modifiable and nonmodifiable factors that impact the hemodynamic balance between placental and cerebral circulations, (3) interventions to improve placental function and protect brain development in utero, and (4) the role of genetic and epigenetic influences on the placenta–heart–brain connection. Impact Neuroplacentology seeks to understand placental connections to fetal brain development. In fetuses with CHD, brain growth abnormalities begin in utero. Placental microstructure as well as perfusion and function are abnormal in fetal CHD.

scholarly journals Maternal psychological distress and child decision-making

2017 ◽  
Vol 218 ◽  
pp. 35-40 ◽  
Author(s):  
Eirini Flouri ◽  
Sofia Ioakeimidi ◽  
Emily Midouhas ◽  
George B. Ploubidis
Keyword(s):  
Decision Making ◽  
Psychological Distress ◽  
Maternal Psychological Distress

Maternal Immune Activation in the Rat Alters Maternofetal Leucine Transport and Fetal Brain Growth

Placenta ◽  
2021 ◽  
Vol 112 ◽  
pp. e13
Author(s):  
Hager M. Kowash ◽  
Harry G. Potter ◽  
Nick Ashton ◽  
Reinmar Hager ◽  
Joanna C. Neill ◽  
...  
Keyword(s):  
Immune Activation ◽  
Fetal Brain ◽  
Brain Growth ◽  
Maternal Immune Activation ◽  
Leucine Transport

scholarly journals Folic Acid Intake, Fetal Brain Growth, and Maternal Smoking in Pregnancy: A Randomized Controlled Trial

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Korede K Yusuf ◽  
Hamisu M Salihu ◽  
Roneé Wilson ◽  
Alfred Mbah ◽  
William Sappenfield ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Folic Acid ◽  
Maternal Smoking ◽  
Controlled Trial ◽  
Fetal Brain ◽  
Brain Growth ◽  
Folic Acid Intake ◽  
Randomized Controlled ◽  
Smoking In Pregnancy ◽  
In Pregnancy

scholarly journals Parental psychological distress during pregnancy and the risk of childhood lower lung function and asthma: a population-based prospective cohort study

Thorax ◽  
2020 ◽  
Vol 75 (12) ◽  
pp. 1074-1081
Author(s):  
Evelien R van Meel ◽  
Gautam Saharan ◽  
Vincent WV Jaddoe ◽  
Johan C de Jongste ◽  
Irwin KM Reiss ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Lung Function ◽  
Prospective Cohort ◽  
Later Life ◽  
Population Based ◽  
Brief Symptom Inventory ◽  
Respiratory Morbidity ◽  
Maternal Psychological Distress ◽  
Increased Risk ◽  
Lower Lung

BackgroundAlthough maternal psychological distress during pregnancy is associated with increased risks of respiratory morbidity in preschool children, it is unknown whether this association persists into later childhood.ObjectiveTo examine the association between parental psychological distress during pregnancy and lung function and asthma in children of school age.MethodsThis study of 4231 children was embedded in a population-based prospective cohort. Parental psychological distress was assessed by the Brief Symptom Inventory during and 3 years after pregnancy, and in mothers also at 2 and 6 months after pregnancy. At age 10 years, lung function was obtained by spirometry and asthma by questionnaire.ResultsThe prevalence of asthma was 5.9%. Maternal overall psychological distress during pregnancy was associated with a lower forced vital capacity (FVC) (z-score difference −0.10 (95% CI −0.20 to –0.01) per 1-unit increase), maternal depressive symptoms during pregnancy with a lower forced expiratory volume in the first second (FEV1) and FVC (−0.13 (95% CI −0.24 to –0.01) and −0.13 (95% CI −0.24 to –0.02) when using clinical cut-offs) in their children. All maternal psychological distress measures during pregnancy were associated with an increased risk of asthma (range OR: 1.46 (95% CI 1.12 to 1.90) to 1.91 (95% CI 1.26 to 2.91)). Additional adjustment for paternal psychological distress during pregnancy and parental psychological distress after pregnancy did not materially change the associations. Paternal psychological distress during pregnancy was not associated with childhood respiratory morbidity.ConclusionMaternal, but not paternal, psychological distress during pregnancy is associated with an increased risk of asthma and partly lower lung function in children. This suggests intrauterine programming for the risk of later-life respiratory disease.

Maternal psychological distress before birth influences gut immunity in mid‐infancy

2020 ◽  
Vol 50 (2) ◽  
pp. 178-188
Author(s):  
Liane J. Kang ◽  
Khanh N. Vu ◽  
Petya T. Koleva ◽  
Catherine J. Field ◽  
Angela Chow ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Maternal Psychological Distress ◽  
Gut Immunity

Prenatal Maternal Psychological Distress and Offspring Risk for Recurrent Respiratory Infections

2019 ◽  
Vol 208 ◽  
pp. 229-235.e1 ◽  
Author(s):  
Laura S. Korhonen ◽  
Linnea Karlsson ◽  
Noora M. Scheinin ◽  
Riikka Korja ◽  
Mimmi Tolvanen ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Respiratory Infections ◽  
Recurrent Respiratory Infections ◽  
Maternal Psychological Distress

Maternal Psychological Distress, Prenatal Cortisol, and Fetal Weight

2006 ◽  
Vol 68 (5) ◽  
pp. 747-753 ◽  
Author(s):  
Miguel A. Diego ◽  
Nancy A. Jones ◽  
Tiffany Field ◽  
Maria Hernandez-Reif ◽  
Saul Schanberg ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Fetal Weight ◽  
Maternal Psychological Distress

Maternal Psychological Distress and Parenting Stress After Gastrostomy Placement in Children

2012 ◽  
Vol 55 (5) ◽  
pp. 562-566 ◽  
Author(s):  
Tone Lise Åvitsland ◽  
Anne Faugli ◽  
Are Hugo Pripp ◽  
Ulrik Fredrik Malt ◽  
Kristin Bjørnland ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Parenting Stress ◽  
Maternal Psychological Distress
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