Chlorhexidine Gluconate, 4%, Showers and Surgical Site Infection Reduction

JAMA Surgery ◽  
2015 ◽  
Vol 150 (11) ◽  
pp. 1033
Author(s):  
Zeinab M. Alawadi ◽  
Lillian S. Kao
Keyword(s):  
Surgical Site Infection ◽  
Chlorhexidine Gluconate ◽  
Site Infection ◽  
Infection Reduction

Surgical Site Infection Reduction in C-Sections

2013 ◽  
Vol 41 (6) ◽  
pp. S46 ◽  
Author(s):  
Ida M. Macri ◽  
John J. Stern ◽  
Debra Runyan ◽  
Tanya Carmichael ◽  
Stacy Giles ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Site Infection ◽  
Infection Reduction

A Glycemic Management Protocol for Surgical Site Infection Reduction in Vascular Surgery

2018 ◽  
Vol 42 (5) ◽  
pp. S9
Author(s):  
Julie Shaw ◽  
Filomena Desousa ◽  
Sylvain Gagne ◽  
James Chan ◽  
Sudhir Nagpal ◽  
...  
Keyword(s):  
Vascular Surgery ◽  
Surgical Site Infection ◽  
Site Infection ◽  
Management Protocol ◽  
Infection Reduction ◽  
Glycemic Management

scholarly journals Standardising intraoperative irrigation with 0.05% chlorhexidine gluconate in caesarean delivery to reduce surgical site infections: A single institution experience

2019 ◽  
Vol 30 (1-2) ◽  
pp. 24-33
Author(s):  
Theresa Mangold ◽  
Erin Kinzel Hamilton ◽  
Helen Boehm Johnson ◽  
Rene Perez
Keyword(s):  
Treatment Group ◽  
Surgical Site Infection ◽  
Infection Rate ◽  
Caesarean Delivery ◽  
Chlorhexidine Gluconate ◽  
Control Group ◽  
Antibiotic Administration ◽  
Site Infection ◽  
Infection Rates ◽  
The Impact

Background Surgical site infection is a significant cause of morbidity and mortality following caesarean delivery. Objective To determine whether standardising intraoperative irrigation with 0.05% chlorhexidine gluconate during caesarean delivery could decrease infection rates. Methods This was a process improvement project involving 742 women, 343 of whom received low-pressured 0.05% chlorhexidine gluconate irrigation during caesarean delivery over a one-year period. Infection rates were compared with a standard-of-care control group (399 women) undergoing caesarean delivery the preceding year. Results The treatment group infection rate met the study goal by achieving a lower infection rate than the control group, though this was not statistically significant. A significant interaction effect between irrigation with 0.05% chlorhexidine gluconate and antibiotic administration time existed, such that infection occurrence in the treatment group was not dependent on antibiotic timing, as opposed to the control group infection occurrence, which was dependent on antibiotic timing. Conclusion Intraoperative irrigation with 0.05% chlorhexidine gluconate during caesarean delivery did not statistically significantly reduce the rate of infections. It did render the impact of antibiotic administration timing irrelevant in prevention of surgical site infection. This suggests a role for 0.05% chlorhexidine gluconate irrigation in mitigating infection risk whether antibiotic prophylaxis timing is suboptimal or ideal.

scholarly journals Should preoperative showering or cleansing with chlorhexidine gluconate (CHG) be part of the surgical care bundle to prevent surgical site infection?

2017 ◽  
Vol 18 (6) ◽  
pp. 311-314 ◽  
Author(s):  
Charles E Edmiston ◽  
David Leaper
Keyword(s):  
Surgical Site Infection ◽  
Risk Reduction ◽  
Low Cost ◽  
Surgical Care ◽  
Infection Risk ◽  
Chlorhexidine Gluconate ◽  
Low Risk ◽  
Care Bundle ◽  
Site Infection ◽  
Methodological Issues

Showering preoperatively with chlorhexidine gluconate is an issue that continues to promote debate; however, many studies demonstrate evidence of surgical site infection risk reduction. Methodological issues have been present in many of the studies used to compile guidelines and there has been a lack of standardisation of processes for application of the active agents in papers pre-2009. This review and commentary paper highlights the potential for enhancing compliance with this low-risk and low-cost intervention and provides some guidance for enhancing implementation of preoperative showering with both chlorhexidine in solution and impregnated wipes.

Evidence for Using Chlorhexidine Gluconate Preoperative Cleansing to Reduce the Risk of Surgical Site Infection

AORN Journal ◽  
2010 ◽  
Vol 92 (5) ◽  
pp. 509-518 ◽  
Author(s):  
Charles E. Edmiston ◽  
Obi Okoli ◽  
Mary Beth Graham ◽  
Sharon Sinski ◽  
Gary R. Seabrook
Keyword(s):  
Surgical Site Infection ◽  
Chlorhexidine Gluconate ◽  
Site Infection

scholarly journals Antisepsys and profilatic antimicrobial therapy in prevention of surgical site infection of horses

2020 ◽  
Vol 72 (1) ◽  
pp. 49-55
Author(s):  
P.A. Canola ◽  
A.P.P.A. Faria ◽  
V.B. Paula ◽  
F.A. Ávila ◽  
M.V. Cardozo ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Ethyl Alcohol ◽  
Bacterial Growth ◽  
Antimicrobial Therapy ◽  
Surgical Procedure ◽  
Chlorhexidine Gluconate ◽  
Site Infection ◽  
Hair Coat ◽  
Duration Of Surgery ◽  
High Level

ABSTRACT The efficacy of an antisepsis protocol comprising chlorhexidine gluconate and ethyl alcohol in combination with prophylactic antimicrobial therapy in controlling surgical site infection in horses was studied. To that purpose, seven mixed breed horses received potassium penicillin and gentamicin at least 30 minutes prior to surgery. The surgical site was scrubbed with chlorhexidine gluconate and rinsed with ethyl alcohol. Samples were collected at four time points: (A) - before and (B) - immediately following shaving of the hair coat, (C) - at the end of antisepsis procedures, and (D) - at the end of the surgical procedure. Duration of surgery was recorded. Samples were cultured in three different culture mediums: Mitis Salivarus (Streptococcus sp.), Staphylococcus 110 (Staphylococcus sp.), and Mac Conkey (Enterobacteria). A high level of bacterial growth was observed in all culture mediums at (A) and (B), with no bacterial growth in (C). Staphylococcus sp. growth was observed in (D) in a single patient whose surgical procedure lasted for 120 minutes. Shaving of the hair coat reduced microbial flora on the surface of the skin. Antisepsis in combination with prophylactic antimicrobial therapy was effective in controlling surgical site infection in elective procedures with an average duration of 90 minutes.

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