Population-based interventions for reducing sexually transmitted infections, including HIV infection

Author(s):  
D Wilkinson ◽  
G Rutherford
1998 ◽  
Vol 9 (9) ◽  
pp. 548-550 ◽  
Author(s):  
M Colvin ◽  
S S Abdool Karim ◽  
C Connolly ◽  
A A Hoosen ◽  
N Ntuli

The objective was to determine the prevalence of HIV and other sexually transmitted infections STIs in a rural community. A population based survey of adults in 110 homesteads was conducted in 1995. A questionnaire on demographics, sexual practices and history of STDs was administered. Neisseria gonorrhoeae and Chlamydia trachomatis infections were detected using ligase chain reaction LCR assay of urine. The seroprevalence of syphilis rapid plasma reagin RPR and Treponema pallidum haemagglutination assay TPHA and HIV infection ELISA was determined. Among 259 subjects the prevalence of HIV was 10.5 , N. gonorrhoeae 4.5 , C. trachomatis 6.1 and active syphilis 8.8 . All infections were asymptomatic. Forty per cent of sexually active men had more than one concurrent sexual partner. Only 14 of subjects had ever used condoms. The STI epidemic is being promoted by high levels of asymptomatic infections, high partner concurrency and low condom use.


Antibiotics ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 929
Author(s):  
Andreas Hahn ◽  
Hagen Frickmann ◽  
Ulrike Loderstädt

Prescribed antibiotic treatments which do not match the therapeutic requirements of potentially co-existing undetected sexually transmitted infections (STIs) can facilitate the selection of antibiotic-drug-resistant clones. To reduce this risk, this modelling assessed the potential applicability of reliable rapid molecular test assays targeting bacterial STI prior to the prescription of antibiotic drugs. The modelling was based on the prevalence of three bacterial STIs in German heterosexual and men-having-sex-with-men (MSM) populations, as well as on reported test characteristics of respective assays. In the case of the application of rapid molecular STI assays for screening, the numbers needed to test in order to correctly identify any of the included bacterial STIs ranged from 103 to 104 for the heterosexual population and from 5 to 14 for the MSM population. The number needed to harm—defined as getting a false negative result for any of the STIs and a false positive signal for another one, potentially leading to an even more inappropriate adaptation of antibiotic therapy than without any STI screening—was at least 208,995 for the heterosexuals and 16,977 for the MSM. Therefore, the screening approach may indeed be suitable to avoid unnecessary selective pressure on bacterial causes of sexually transmitted infections.


JAMA ◽  
2019 ◽  
Vol 321 (14) ◽  
pp. 1380 ◽  
Author(s):  
Michael W. Traeger ◽  
Vincent J. Cornelisse ◽  
Jason Asselin ◽  
Brian Price ◽  
Norman J. Roth ◽  
...  

Author(s):  
N. Saravanan ◽  
Murugan Swamiappan ◽  
Rajkumar Kannan ◽  
G. Arul Raja

<p class="abstract"><strong>Background:</strong> Sexually transmitted infections (STIs) are the most well established risk factors for the spread of HIV infection. STIs act as cofactors and facilitators for HIV transmission. The effects of HIV infection on immunity can increase susceptibility to other STIs. The aims and objectives of the study were to determine the prevalence of co-infection of sexually transmitted infections among people living with HIV and AIDS.</p><p class="abstract"><strong>Methods:</strong> A retrospective chart review of the data collected from the clinical records of all HIV patients who had attended the STI clinic of Chengalpattu Medical College, Chengalpattu, Tamil Nadu during the five years period, from January 2013 to December 2017, was carried out. Demographic data, clinical manifestations, co-infection of STIs among HIV patients, laboratory investigations and treatment were collected. The data collected were computed and analyzed statistically.<strong></strong></p><p class="abstract"><strong>Results:</strong> During the study period of 5 years from 2013 to 2017 the total number of patients attended the STI clinic were 10825, among that males were 4534 (41.88%) and females were 6291 (58.12%). STIs/RTIs were seen in 2560 (23.65%) cases among the total number of patients attended. HIV was found to be positive in 294 cases, in that 168 (57.15%) were males and 126 (42.85%) were females. In male HIV patients, 51 (30.36%) had co-infection with other STIs/RTIs. In female HIV patients, 57 (45.24) % had co-infection with other STIs/RTIs. Viral STIs was the common co-infection seen in males and vaginal cervical discharge was common in females.</p><p class="abstract"><strong>Conclusions:</strong> STI/RTI co-infection, both symptomatic and asymptomatic are common among PLHIV. Hence they should be regularly counselled regarding the significance of periodic screening for STI/RTIs avoidance of high risk sexual behaviour.</p>


Sign in / Sign up

Export Citation Format

Share Document