Proteomic Applications of Plasmonic Sensors

Author(s):  
Duygu Çimen ◽  
Merve Asena Özbek ◽  
Nilay Bereli ◽  
Adil Denizli
Keyword(s):  
Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5262
Author(s):  
Qilin Duan ◽  
Yineng Liu ◽  
Shanshan Chang ◽  
Huanyang Chen ◽  
Jin-hui Chen

Surface plasmonic sensors have been widely used in biology, chemistry, and environment monitoring. These sensors exhibit extraordinary sensitivity based on surface plasmon resonance (SPR) or localized surface plasmon resonance (LSPR) effects, and they have found commercial applications. In this review, we present recent progress in the field of surface plasmonic sensors, mainly in the configurations of planar metastructures and optical-fiber waveguides. In the metastructure platform, the optical sensors based on LSPR, hyperbolic dispersion, Fano resonance, and two-dimensional (2D) materials integration are introduced. The optical-fiber sensors integrated with LSPR/SPR structures and 2D materials are summarized. We also introduce the recent advances in quantum plasmonic sensing beyond the classical shot noise limit. The challenges and opportunities in this field are discussed.


2021 ◽  
Author(s):  
Changhyoup Lee ◽  
Benjamin Lawrie ◽  
Raphael Pooser ◽  
Kwang-Geol Lee ◽  
Carsten Rockstuhl ◽  
...  
Keyword(s):  

Plasmonics ◽  
2017 ◽  
Vol 13 (2) ◽  
pp. 493-502 ◽  
Author(s):  
Christina Christopher ◽  
A. Subrahmanyam ◽  
V. V. R. Sai

Author(s):  
Franco Marabelli ◽  
Andrea Valsesia ◽  
Silvia Giudicatti ◽  
Lucia Fornasari ◽  
Paola Pellacani ◽  
...  

2008 ◽  
Vol 108 (2) ◽  
pp. 494-521 ◽  
Author(s):  
Matthew E. Stewart ◽  
Christopher R. Anderton ◽  
Lucas B. Thompson ◽  
Joana Maria ◽  
Stephen K. Gray ◽  
...  
Keyword(s):  

2021 ◽  
Author(s):  
Mariachiara Manoccio ◽  
Marco Esposito ◽  
Elisabetta Primiceri ◽  
Angelo Leo ◽  
Vittorianna Tasco ◽  
...  

Abstract Advanced sensing tools capable to detect extremely low concentrations of circulating biomarkers can open unexplored routes towards early diagnostics of diseases and their progression monitoring. Plasmonic sensors are an emerging technology enabling different optical effects that can be used as molecular tracking solutions. Here we demonstrate the sensing capabilities of a chip-based metamaterial, combining the 3D chiral geometry with an optically functional core-shell architecture. The sensor can be easily handled and exhibits reliability and stability during the whole functionalization and analytical procedure thanks to the on-chip format. The system shows a linear shift of circular dichroism spectrum upon interaction with different concentrations of TAR DNA-binding protein TDP-43, a clinically relevant biomarker for neurodegenerative disease screening. The measurements were performed in spiked solution as well as in human serum, with concentrations from 1pM down to 10fM, a range not accessible with commonly used immunological assays and that can thus open new perspectives for disease knowledge and early diagnostics.


Author(s):  
F. Bahrami ◽  
M. Maisonneuve ◽  
M. Meunier ◽  
J. S. Aitchison ◽  
M. Mojahedi
Keyword(s):  

2020 ◽  
Vol 10 (12) ◽  
pp. 4389 ◽  
Author(s):  
Nunzio Cennamo ◽  
Francesco Arcadio ◽  
Aldo Minardo ◽  
Domenico Montemurro ◽  
Luigi Zeni

In this work, we have compared several configurations of surface plasmon resonance (SPR) sensors based on D-shaped tapered plastic optical fibers (TPOFs). Particularly, the TPOFs used to obtain the SPR sensors are made by a lab-built system based on two motorized linear positioning stages and a heating plate. Preliminarily, a comparative analysis has been carried out between two different configurations, one with and one without a thin buffer layer deposited between the core of TPOFs and the gold film. After this preliminary step, we have used the simpler configuration, obtained without the buffer layer, to realize different SPR D-shaped TPOF sensors. This study could be of interest in SPR D-shaped multimode plastic optical fiber (POF) sensors because, without the tapers, the performances decrease when the POF’s diameter decreases, whereas the performances improve in SPR D-shaped tapered POF sensors, where the diameter decreases in the D-shaped sensing area. The performances of the SPR sensors based on different taper ratios have been analyzed and compared. The SPR-TPOF sensors have been tested using water–glycerin mixtures with refractive indices ranging from 1.332 to 1.381 RIU. According to the theory, the experimental results have demonstrated that, as the taper ratio increases, the sensitivity of the SPR sensor increases as well, while on the contrary the signal-to-noise ratio (SNR) decreases.


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