Normally Oriented Adhesion versus Friction Forces in Bacterial Adhesion to Polymer-Brush Functionalized Surfaces Under Fluid Flow

2014 ◽  
Vol 24 (28) ◽  
pp. 4435-4441 ◽  
Author(s):  
Jan J. T. M. Swartjes ◽  
Deepak H. Veeregowda ◽  
Henny C. van der Mei ◽  
Henk J. Busscher ◽  
Prashant K. Sharma
2011 ◽  
Vol 87 (1) ◽  
pp. 109-115 ◽  
Author(s):  
Bing Fang ◽  
Saugata Gon ◽  
Myoung Park ◽  
Kushi-Nidhi Kumar ◽  
Vincent M. Rotello ◽  
...  

Biomaterials ◽  
2008 ◽  
Vol 29 (30) ◽  
pp. 4117-4121 ◽  
Author(s):  
M. Reza Nejadnik ◽  
Henny C. van der Mei ◽  
Willem Norde ◽  
Henk J. Busscher

Author(s):  
Narendra Pal Singh Chauhan ◽  
Sangeeta Kalal ◽  
Priya Juneja ◽  
Pinki B. Punjabi

2019 ◽  
Vol 5 (10) ◽  
pp. 4920-4936 ◽  
Author(s):  
Fiorela Ghilini ◽  
Diego E. Pissinis ◽  
Alejandro Miñán ◽  
Patricia L. Schilardi ◽  
Carolina Diaz

2007 ◽  
Vol 74 (3) ◽  
pp. 916-919 ◽  
Author(s):  
M. Reza Nejadnik ◽  
Henny C. van der Mei ◽  
Henk J. Busscher ◽  
Willem Norde

ABSTRACT We introduce a procedure for determining shear forces at the balance between attachment and detachment of bacteria under flow. This procedure can be applied to derive adhesion forces in weak-adherence systems, such as polymer brush coatings, which are currently at the center of attention for their control of bacterial adhesion and biofilm formation.


2009 ◽  
Vol 3 (4) ◽  
Author(s):  
Eric Busillo ◽  
Jonathan S. Colton

A significant potential for plastic hypodermic needles exists as an alternative to current steel needles. This paper presents the design and testing of one type of plastic hypodermic needle. The buckling and penetration characteristics of the needles were modeled and analyzed analytically and by finite element analyses. Experimental penetration tests using plastic and steel control hypodermic needles with skin mimics, specifically polyurethane film and pig skin, were performed to determine penetration and friction forces. Lubricated plastic needles achieved successful penetrations in 25–75% of the tests in both polyurethane film and pig skin with penetration forces ranging from 7 N to 10 N. Penetration tests into butyl rubber stoppers also were conducted with lubricated plastic needles penetrating in 75% of the tests with an average penetration force of 8.3 N. Various lubricants, including silicone oil and a medical grade silicone dispersion, were also studied. In addition, the needles underwent successful perpendicular bending tests and cannula stiffness tests. Finally, fluid flow tests determined fluid flow rates through the needles. Experimental results were compared with each other and to finite element analyses and are discussed.


2013 ◽  
Vol 46 (17) ◽  
pp. 7018-7026 ◽  
Author(s):  
Wei Sun ◽  
Shouxue Zhou ◽  
Bo You ◽  
Limin Wu

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Monica Thukkaram ◽  
Soundarya Sitaram ◽  
Sathish kumar Kannaiyan ◽  
Guruprakash Subbiahdoss

Biofilm growth on the implant surface is the number one cause of the failure of the implants. Biofilms on implant surfaces are hard to eliminate by antibiotics due to the protection offered by the exopolymeric substances that embed the organisms in a matrix, impenetrable for most antibiotics and immune cells. Application of metals in nanoscale is considered to resolve biofilm formation. Here we studied the effect of iron-oxide nanoparticles over biofilm formation on different biomaterial surfaces and pluronic coated surfaces. Bacterial adhesion for 30 min showed significant reduction in bacterial adhesion on pluronic coated surfaces compared to other surfaces. Subsequently, bacteria were allowed to grow for 24 h in the presence of different concentrations of iron-oxide nanoparticles. A significant reduction in biofilm growth was observed in the presence of the highest concentration of iron-oxide nanoparticles on pluronic coated surfaces compared to other surfaces. Therefore, combination of polymer brush coating and iron-oxide nanoparticles could show a significant reduction in biofilm formation.


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