Gray matter heterotopias and brachytelephalangic chondrodysplasia punctata: A complication of hyperemesis gravidarum induced vitamin K deficiency?

2007 ◽  
Vol 143A (2) ◽  
pp. 200-204 ◽  
Author(s):  
Nicola Brunetti-Pierri ◽  
Jill V. Hunter ◽  
Cornelius F. Boerkoel
Keyword(s):  
Vitamin K ◽  
Gray Matter ◽  
Hyperemesis Gravidarum ◽  
Chondrodysplasia Punctata ◽  
Vitamin K Deficiency ◽  
K Deficiency

scholarly journals Intraperitoneal Hemorrhage in a Pregnant Woman with Hyperemesis Gravidarum: Vitamin K Deficiency as a Possible Cause

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Yosuke Baba ◽  
Hiroyuki Morisawa ◽  
Koyomi Saito ◽  
Hironori Takahashi ◽  
Kazuma Rifu ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Vitamin K ◽  
Pain Treatment ◽  
Hyperemesis Gravidarum ◽  
Japanese Woman ◽  
Hemorrhagic Diathesis ◽  
Vitamin K Deficiency ◽  
Vitamin Deficiencies ◽  
K Deficiency

Hyperemesis gravidarum can cause various vitamin deficiencies. Vitamin K deficiency can lead to coagulopathy or hemorrhagic diathesis. A nulliparous Japanese woman with hyperemesis gravidarum at 105/7weeks was admitted with giant myoma, intestinal obstruction, and abdominal pain. Treatment for a degenerative myoma was instituted with intravenous antibiotics. The abdominal pain ameliorated, but intestinal obstruction persisted. At 166/7weeks, we performed laparotomy for release of intestinal obstruction, when intraabdominal bleeding of 110 mL existed. Blood tests revealed coagulopathy secondary to vitamin K deficiency. The coagulopathy responded to intravenous vitamin K injection. Coagulopathy due to vitamin K deficiency can occur with hyperemesis gravidarum, and coexisting intestinal obstruction and broad-spectrum antibiotics can aggravate the deficiency.

scholarly journals Vitamin K Deficiency Embryopathy from Hyperemesis Gravidarum

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Andrew S. Lane ◽  
Jennifer L. Stallworth ◽  
Kacey Y. Eichelberger ◽  
Kenneth F. Trofatter
Keyword(s):  
Vitamin K ◽  
Enteral Feeding ◽  
Hyperemesis Gravidarum ◽  
Severe Form ◽  
Common Condition ◽  
Vitamin K Deficiency ◽  
Facial Profile ◽  
Prepregnancy Weight ◽  
K Deficiency ◽  
Nasal Hypoplasia

A 21-year-old primigravida had a pregnancy complicated by hyperemesis gravidarum (HG) beginning at 7-week gestation. Despite medical therapy, she lost 18% of her prepregnancy weight. Early ultrasound at 14 weeks demonstrated a flattened facial profile with nasal hypoplasia (Binder phenotype) consistent with vitamin K deficiency from HG. She had a percutaneous endoscopic gastrojejunostomy tube placed for enteral feeding at 15-week gestation. At repeated anatomy ultrasound at 21-week gestation, delivery, and postnatal pediatric genetics exam, nasal hypoplasia was consistent with vitamin K deficiency embryopathy from HG. Nausea and vomiting of pregnancy is a common condition. HG, the most severe form, has many maternal and fetal effects. Evaluation of vitamin K status could potentially prevent this rare and disfiguring embryopathy.

Vitamin K deficiency in hyperemesis gravidarum as a potential cause of fetal intracranial hemorrhage and hydrocephalus

2007 ◽  
Vol 28 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Yukie Kawamura ◽  
Kazuya Kawamata ◽  
Mitsuhisa Shinya ◽  
Michiyo Higashi ◽  
Masaki Niiro ◽  
...  
Keyword(s):  
Intracranial Hemorrhage ◽  
Vitamin K ◽  
Hyperemesis Gravidarum ◽  
Vitamin K Deficiency ◽  
K Deficiency

COAGULOPATHY SECONDARY TO VITAMIN K DEFICIENCY IN HYPEREMESIS GRAVIDARUM

1998 ◽  
Vol 92 (Supplement) ◽  
pp. 673-675
Author(s):  
Julian N. Robinson ◽  
Rini Banerjee ◽  
Mari-Paule Thiet
Keyword(s):  
Vitamin K ◽  
Hyperemesis Gravidarum ◽  
Vitamin K Deficiency ◽  
K Deficiency
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