The novel and recurrent variants in exon 31 of CREBBP in Japanese patients with Menke–Hennekam syndrome

Author(s):  
Eriko Nishi ◽  
Toshiki Takenouchi ◽  
Fuyuki Miya ◽  
Tomoko Uehara ◽  
Kumiko Yanagi ◽  
...  
2006 ◽  
Vol 56 (6) ◽  
pp. 1193-1196 ◽  
Author(s):  
Soji Iida ◽  
Akiko Kageyama ◽  
Katsukiyo Yazawa ◽  
Noboru Uchiyama ◽  
Takafumi Toyohara ◽  
...  

Two bacterial strains isolated from different hospitals in Japan were subjected to a polyphasic analysis. Strains IFM 0803T and IFM 10383 were found to have morphological, biochemical, physiological and chemotaxonomic properties consistent with their classification in the genus Nocardia. Strains IFM 0803T and IFM 10383 clustered with the type strain of Nocardia xishanensis, showing 16S rRNA gene sequence similarities of 98.6–98.9 % with this species. The novel strains could be distinguished from N. xishanensis by a range of phenotypic properties. Based on their phenotypic and phylogenetic characteristics, the two isolates are proposed as members of a novel species of the genus Nocardia, Nocardia exalbida sp. nov., with the type strain IFM 0803T (=NBRC 100660T=JCM 12667T=DSM 44883T).


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