Asymmetric Dearomatization of Indole by Palladium/PC‐Phos‐Catalyzed Dynamic Kinetic Transformation

The excited compound nucleus 17O* has been studied over (n,α) and (α,n) cross sections modelling, respectively for 16O and 13C targets in their ground states. The modelling is fulfilled within the Reich-Moore formalism. We were able to calculate the (α,n) cross section by two separate ways: the direct kinematic standard route and by inversion of the (n,α) cross section using the compound nucleus hypothesis. Resonance parameters of the resolved resonance range (0 to 6 MeV) were borrowed from the CIELO project. In a first stage, the modelling is carried out in the referential of the incident particle (either way neutron or α) requesting conversion of the CIELO neutron-type resonance parameters to the α-type. In a second stage, the implementation is uniquely designed in the center of mass system of the excited compound nucleus. The resonance parameters are thus converted in that unique reference framework. The present investigation shows the consistency of the kinetic transformation that relies on the compound nucleus hypothesis.

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Designing Architectural Morphing Skins with Elastic Modular Systems

International Journal of Architectural Computing ◽

10.1260/1478-0771.9.4.397 ◽

2011 ◽

Vol 9 (4) ◽

pp. 397-419 ◽

Cited By ~ 14

Author(s):

Chin Koi Khoo ◽

Flora Salim ◽

Jane Burry

Keyword(s):

Climatic Conditions ◽

Existing Buildings ◽

Physical Computation ◽

Modular Systems ◽

Mechanical Joints ◽

Kinetic Transformation ◽

Elastic Form ◽

Shading Devices ◽

Design Experiments

This paper discusses the issues of designing architectural skins that can be physically morphed to adapt to changing needs. To achieve this architectural vision, designers have focused on developing mechanical joints, components, and systems for actuation and kinetic transformation. However, the unexplored approach of using lightweight elastic form-changing materials provides an opportunity for designing responsive architectural skins and skeletons with fewer mechanical operations. This research aims to develop elastic modular systems that can be applied as a second skin or brise-soleil to existing buildings. The use of the second skin has the potential to allow existing buildings to perform better in various climatic conditions and to provide a visually compelling skin. This approach is evaluated through three design experiments with prototypes, namely Tent, Curtain and Blind, to serve two fundamental purposes: Comfort and Communication. These experimental prototypes explore the use of digital and physical computation embedded in form-changing materials to design architectural morphing skins that manipulate sunlight and act as responsive shading devices.

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Asymmetric Dearomatization of Indole by Palladium/PC‐Phos‐Catalyzed Dynamic Kinetic Transformation

Angewandte Chemie International Edition ◽

10.1002/anie.202010164 ◽

2020 ◽

Vol 59 (49) ◽

pp. 21991-21996

Author(s):

Haoke Chu ◽

Jie Cheng ◽

Junfeng Yang ◽

Yin‐Long Guo ◽

Junliang Zhang

Keyword(s):

Kinetic Transformation

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Theoretical Investigation on Mechanistic and Kinetic Transformation of 2,2′,4,4′,5-Pentabromodiphenyl Ether

The Journal of Physical Chemistry A ◽

10.1021/acs.jpca.5b04022 ◽

2015 ◽

Vol 119 (24) ◽

pp. 6404-6411 ◽

Cited By ~ 15

Author(s):

Haijie Cao ◽

Dandan Han ◽

Mingyue Li ◽

Xin Li ◽

Maoxia He ◽

...

Keyword(s):

Theoretical Investigation ◽

Kinetic Transformation

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Cu-catalyzed asymmetric addition of sp2-hybridized zirconium nucleophiles to racemic allyl bromides

Chemical Communications ◽

10.1039/c5cc00421g ◽

2015 ◽

Vol 51 (24) ◽

pp. 5044-5047 ◽

Cited By ~ 30

Author(s):

Mireia Sidera ◽

Stephen P. Fletcher

Keyword(s):

Allylic Alkylation ◽

Asymmetric Allylic Alkylation ◽

Asymmetric Addition ◽

Kinetic Transformation

Asymmetric allylic alkylation with sp2 hybridized zirconium nucleophiles via a dynamic kinetic transformation is reported.

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Dynamic Kinetic Transformation of Sulfinyl Chlorides: Synthesis of Enantiomerically PureC2-Symmetric Bis-Sulfoxides

The Journal of Organic Chemistry ◽

10.1021/jo0159183 ◽

2002 ◽

Vol 67 (2) ◽

pp. 345-356 ◽

Cited By ~ 42

Author(s):

Noureddine Khiar ◽

Cristina S. Araújo ◽

Felipe Alcudia ◽

Inmaculada Fernández

Keyword(s):

Kinetic Transformation

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Synthesis of ZIF-67 and ZIF-8 crystals using DMSO (Dimethyl Sulfoxide) as solvent and kinetic transformation studies

Journal of Crystal Growth ◽

10.1016/j.jcrysgro.2016.10.016 ◽

2016 ◽

Vol 455 ◽

pp. 152-156 ◽

Cited By ~ 21

Author(s):

Xuhui Feng ◽

Ting Wu ◽

Moises A. Carreon

Keyword(s):

Dimethyl Sulfoxide ◽

Kinetic Transformation

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Effect of pH on the Hydrolytic Kinetics of Gamma-Glutamyl Transferase fromBacillus subtilis

The Scientific World JOURNAL ◽

10.1155/2014/216270 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Sharath Balakrishna ◽

Asmita Prabhune

Keyword(s):

Conformational Changes ◽

Quaternary Structure ◽

Gamma Glutamyl Transferase ◽

Effect Of Ph ◽

Gamma Glutamyl ◽

Steady State Kinetics ◽

Kinetic Transformation ◽

Ph Range ◽

Glutamyl Transferase ◽

Kinetics Of

The effect of pH on the steady state kinetics of gamma-glutamyl transferase (GGT) fromBacillus subtiliswas examined using glutamyl-(3-carboxyl)-4-nitroanilide as the chromogenic reporter substrate. The enzyme was active in the pH range 7.0–11.0 with the optimum activity at pH 11.0. We noticed a pH dependent transformation in the nature of substrate consumption kinetics. The substrate saturation curves were hyperbolic in the pH range 7.0–9.0 but changed into sigmoid form at pH 10.0 and 11.0. Hill’s coefficients were >1. We also analysed the effect of pH on the structure of the enzyme. The circular dichroism spectra of the enzyme sample at pH 9.0 and 11.0 were coincidental in both far and near UV regions indicating conservation of the secondary and tertiary structures, respectively. The molecular weight of the enzyme sample was the same in both pH 7.0 and 11.0 indicating conservation of the quaternary structure. These results show that the kinetic transformation does not involve significant conformational changes. Cooperative binding of multiple substrate molecules may not be the basis for the sigmoid kinetics as only one substrate binding site has been noticed in the reported crystal structures ofB. subtilisGGT.

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Palladium-Catalyzed Asymmetric Hydrophosphination of Internal Alkynes: Highly Regio- and Stereoselective Construction of Axially Chiral Phosphines

10.26434/chemrxiv-2021-8rtq4 ◽

2021 ◽

Author(s):

Danqing Ji ◽

Jierui Jing ◽

Yi Wang ◽

Zisong Qi ◽

Fen Wang ◽

...

Keyword(s):

Axial Chirality ◽

Axially Chiral ◽

Internal Alkynes ◽

Trisubstituted Olefins ◽

Palladium Catalyzed ◽

Chiral Phosphines ◽

Kinetic Transformation ◽

Secondary Phosphines

Palladium-catalyzed unprecedented atroposelective hydrophosphination of internal alkynes has been realized using diarylphosphines, affording C-N axially chiral trisubstituted olefins (vinylphosphines) in excellent regioselectiviry, (E)-selectivity, and enantioselectivity. The axial chirality was established via integration of hydrophosphination and dynamic kinetic transformation of the alkynes, with both symmetrical and nonsymmetrical secondary phosphines being applicable. In the latter case, additional P-central chirality has been constructed in good diastereoselectivity.

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