scholarly journals Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis

2021 ◽  
Author(s):  
Robin Teufel ◽  
Marina Toplak ◽  
Raspudin Saleem-Batcha ◽  
Jörn Piel
Keyword(s):  
Polyketide Biosynthesis

Polyketide biosynthesis in dinoflagellates: what makes it different?

2014 ◽  
Vol 31 (9) ◽  
pp. 1101 ◽  
Author(s):  
Ryan M. Van Wagoner ◽  
Masayuki Satake ◽  
Jeffrey L. C. Wright
Keyword(s):  
Polyketide Biosynthesis

Biosynthesis of fungal polyketides by collaborating and trans-acting enzymes

2022 ◽  
Author(s):  
Elizabeth Skellam
Keyword(s):  
Polyketide Biosynthesis

Investigations into fungal polyketide biosynthesis have revealed many examples of megasynthases and trans-acting accessory enzymes. This review collates the different classes of collaborating enzymes, demonstrating common themes and rarer examples.

scholarly journals Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase

2016 ◽  
Vol 473 (8) ◽  
pp. 1097-1110 ◽  
Author(s):  
Steven Vance ◽  
Olga Tkachenko ◽  
Ben Thomas ◽  
Mona Bassuni ◽  
Hui Hong ◽  
...  
Keyword(s):  
Polyketide Synthase ◽  
Acyl Carrier Protein ◽  
Protein Domain ◽  
Carrier Protein ◽  
Protein Surface ◽  
Prosthetic Group ◽  
Polyketide Biosynthesis ◽  
Covalently Linked

When covalently linked to an acyl carrier protein (ACP) and loaded with acyl substrate-mimics, some 4′-phosphopantetheine prosthetic group arms swing freely, whereas others stick to the protein surface, suggesting a possible mode of interaction with enzyme domains during polyketide biosynthesis.

Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans

2012 ◽  
Vol 160 (1-2) ◽  
pp. 64-71 ◽  
Author(s):  
Anindita Sarkar ◽  
Alexander N. Funk ◽  
Kirstin Scherlach ◽  
Fabian Horn ◽  
Volker Schroeckh ◽  
...  
Keyword(s):  
Differential Expression ◽  
Aspergillus Nidulans ◽  
Gene Clusters ◽  
Polyketide Biosynthesis ◽  
Chemostat Cultures ◽  
Biosynthesis Gene
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