The High-Yield Synthesis and Characterization of the First Porphyrin–Cyclam Dinucleating Ligand and Its Iron(III)/Copper(II) Complex

Preparative methods have been explored for the synthesis of small, volatile polysilaalkanes, which could serve as starting materials for the production of amorphous silicon a-SiC:H. High yield pathways have been developed for H3SiCH2CH2SiH3 and H3SiCH2CH2CH2SiH3. These compounds can be converted into symmetrically halogen-functional derivatives through the reactions with SnCl4 or Br2. The homologous H3SiCH2CH2SiH2CH3 has also been prepared and halogenated, starting from the corresponding vinylsilane via the hydrosilylation route. Allylsilanes were the source of the synthesis of H3SiCH2CH=CH2, CH3SiH2CH2CH=CH, SiH2(CH2CH = CH2)2, SiH2(CH2CH2CH2SiH3)2, or HSi(CH2CH2CH2SiH3)3. Methylated derivatives are also available. - Some physical and spectroscopic properties of the new compounds have been investigated. In particular. NMR data were collected and used for an assessment of structure and isomerism.

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Environmentally benign synthesis of methyl 6-amino-5-cyano-4-aryl-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates using CeO2 nanoparticles as a reusable and robust catalyst

Zeitschrift für Naturforschung B ◽

10.1515/znb-2016-0119 ◽

2016 ◽

Vol 71 (11) ◽

pp. 1135-1140 ◽

Cited By ~ 2

Author(s):

Javad Safaei-Ghomi ◽

Mehrnoosh Asgari-Kheirabadi ◽

Hossein Shahbazi-Alavi

Keyword(s):

Condensation Reaction ◽

Ceo2 Nanoparticles ◽

Environmentally Benign ◽

High Yield ◽

Synthesis And Characterization ◽

Dimethyl Acetylenedicarboxylate ◽

One Pot ◽

Efficient Catalyst ◽

Benign Synthesis

AbstractIn this work, we report the synthesis and characterization of CeO2 nanoparticles as an efficient catalyst for the preparation of methyl 6-amino-5-cyano-4-aryl-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates via one-pot four-component condensation reaction of dimethyl acetylenedicarboxylate, hydrazine hydrate, malononitrile, and aldehydes in aqueous medium. The use of a non-hazardous organic solvent, easy recovery of the catalyst, compatibility with various functional groups, and high yield of the products make the protocol attractive, greener, and economic.

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Synthesis and Characterization of Novel 1,3-Thiazole and 2-Amino-1,3,4-Thiadiazole Derivatives

Macedonian Journal of Chemistry and Chemical Engineering ◽

10.20450/mjcce.2014.522 ◽

2014 ◽

Vol 33 (2) ◽

pp. 189 ◽

Cited By ~ 9

Author(s):

Mustafa Er ◽

Ayşe Şahin ◽

Hakan Tahtacı

Keyword(s):

Biological Activities ◽

High Yield ◽

Synthesis And Characterization ◽

Hantzsch Reaction ◽

H Nmr ◽

Thiadiazole Derivatives ◽

High Yields ◽

Mass Spectrometric Techniques ◽

C Nmr

Thiosemicarbazone derivatives 3a–e were synthesized by the reaction of various aldehydes 1a–e with 4-methyl thiosemicarbazide 2 in 78% to 90% yield. Then, the thiazole moieties of the target materials 5a–e were obtained in high yields (71–93%) using the Hantzsch reaction utilizing thiosemicarbazone derivatives 3a–e with ethyl-2-chloroacetoacetic ester. The substituted nitrile derivatives 7a–e were obtained in moderate to high yield (58–84%) from the reaction of compounds 5a–e with chloroacetonitrile by the nucleophilic aliphatic substitution reaction in the presence of anhydrous potassium carbonate. Finally, substituted 2-amino-1,3,4-thiadiazole compounds 9a–e were obtained in moderate to good yields (51–62%) from the reaction of thiosemicarbazide with substituted nitrile derivatives 7a–e. As a result, compounds that all share a high disposition for biological activities were obtained. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, elemental analysis, and mass spectrometric techniques.

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