Potent Cyclic Tetrapeptide for Lead Detoxification

Author(s):  
Tagwa A. Mohammed ◽  
Christoph M. Meier ◽  
Tadeáš Kalvoda ◽  
Martina Kalt ◽  
Lubomír Rulíšek ◽  
...  
Keyword(s):  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.


ChemInform ◽  
2010 ◽  
Vol 33 (38) ◽  
pp. no-no
Author(s):  
Zhong Jiang ◽  
Marc-Olivier Barret ◽  
Kenneth G. Boyd ◽  
David R. Adams ◽  
Alan S. F. Boyd ◽  
...  

2015 ◽  
Vol 13 ◽  
pp. 11-14 ◽  
Author(s):  
Amgad I.M. Khedr ◽  
Gamal A. Mohamed ◽  
Mohamed A.A. Orabi ◽  
Sabrin R.M. Ibrahim ◽  
Koji Yamada

2017 ◽  
Vol 32 (14) ◽  
pp. 1627-1631 ◽  
Author(s):  
Chun-Lan Xie ◽  
Siwen Niu ◽  
Jin-Mei Xia ◽  
Kun Peng ◽  
Gai-Yun Zhang ◽  
...  

2006 ◽  
Vol 12 (7) ◽  
pp. 491-496 ◽  
Author(s):  
Puig Mora ◽  
Carlos Mas-Moruno ◽  
Silvia Tamborero ◽  
Luis J. Cruz ◽  
Enrique PÉrez-PayÁ ◽  
...  

2019 ◽  
Vol 17 (16) ◽  
pp. 3902-3913
Author(s):  
Alan J. Cameron ◽  
Christopher J. Squire ◽  
Ashley Gérenton ◽  
Louise A. Stubbing ◽  
Paul W. R. Harris ◽  
...  

During total synthesis of pseudoxylallemycin A, an unstable intermediate was observed and appeared to be reactivated by coupling reagent by-products.


2001 ◽  
Vol 42 (43) ◽  
pp. 7555-7558 ◽  
Author(s):  
Susanne Pohl ◽  
Richard Goddard ◽  
Stefan Kubik

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