DNA binding, cleavage, docking, biological and kinetic studies of Cr(III), Fe(III), Co(II) and Cu(II) complexes with ortho‐vanillin Schiff base derivative

2021 ◽  
Author(s):  
Kavitha Bengi ◽  
Sravanthi Maddikayala ◽  
Saritha Reddy Pulimamidi
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Kinetic Studies ◽  
Base Derivative

A New Isoindoline Based Schiff Base Derivative as Cu(II) Chemosensor: Synthesis, Photophysical, DNA Binding and Molecular Docking Studies

2015 ◽  
Vol 25 (6) ◽  
pp. 1763-1773 ◽  
Author(s):  
Pattan Sirajuddin Nayab ◽  
Madhusudana Pulaganti ◽  
Suresh Kumar Chitta ◽  
Rahisuddin
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dna Binding ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Base Derivative

Fluorenone Schiff base derivative complexes of ruthenium, rhodium and iridium exhibiting efficient antibacterial activity and DNA-binding affinity

2020 ◽  
Vol 915 ◽  
pp. 121246
Author(s):  
Mohan Rao Kollipara ◽  
Lathewdeipor Shadap ◽  
Venkanna Banothu ◽  
Nipanshu Agarwal ◽  
Krishna Mohan Poluri ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Dna Binding ◽  
Binding Affinity ◽  
Base Derivative ◽  
Dna Binding Affinity

scholarly journals DNA binding properties of 2ʹ-hydroxyflavanon and Schiff base derivative

2019 ◽  
Vol 64 (2) ◽  
pp. 222-228
Author(s):  
V. M. Korolevich ◽  
P. Blazinska ◽  
A. Sykula ◽  
E. Lodyga-Chruscinska
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Spectroscopic Properties ◽  
Binding Properties ◽  
Base Modification ◽  
Whole Plant ◽  
Base Derivative ◽  
Anti Inflammatory ◽  
Dna Binding Properties

Flavanoids a class of plant and fungus secondary metabolites. 2ʹ-Hydroxyflavanone was previously isolated from Mimosa pudica (L.) whole plant and was found to exhibit anti-inflammatory effects in vitro and binding with calf timus DNA. There are also reports on anti-inflammatory properties of compounds bearing flavanone/chromone nucleus. The aim of this work was to develop a synthesis of new azomethine compounds derived from flavanones, to examine their spectroscopic properties and interaction with DNA. 2ʹ-Hydroxyflavanone and thiocarbohydrazide were used as substrates in the synthesis. The obtained products were analyzed by 1H NMR spectroscopy, UVVis. Ultraviolet spectroscopy was used to analyze the chemical-physical properties. Mechanism of interaction of bioactive 2ʹ-hydroxyflavanone with calf thymus deoxyribonucleic acid (DNA) was studied employing UV absorption. 2ʹ-Hydroxyflavanon and 2ʹHFTCH are photostable in DMSO. The interaction of 2ʹ-hydroxyflavanone and its derivative occurs by the mechanism of intercalation. The change in the structure of the 2ʹ-hydroxyflavanone molecule by Schiff base modification leads to an increase in DNA-binding properties. High binding ability of 2ʹ-hydroxyflavanone with DNA may be useful for development of new anti-inflammatory and antimicrobial remedies.

Efficient Preconcentration of Cu2+, Zn2+ and Fe3+ with an Agarose-Schiff Base Sorbent

2007 ◽  
Vol 72 (7) ◽  
pp. 908-916 ◽  
Author(s):  
Payman Hashemi ◽  
Hatam Hassanvand ◽  
Hossain Naeimi
Keyword(s):  
Schiff Base ◽  
Metal Ions ◽  
Metal Ion ◽  
Good Accuracy ◽  
Kinetic Studies ◽  
Sample Volume ◽  
Effects Of Ph ◽  
Glass Column ◽  
High Concentrations ◽  
Ph Range

Sorption and preconcentration of Cu2+, Zn2+ and Fe3+ on a salen-type Schiff base, 2,2'- [ethane-1,2-diylbis(nitrilomethylidyne)]bis(2-methylphenol), chemically immobilized on a highly crosslinked agarose support, were studied. Kinetic studies showed higher sorption rates of Cu2+ and Fe3+ in comparison with Zn2+. Half-times (t1/2) of 31, 106 and 58 s were obtained for sorption of Cu2+, Zn2+ and Fe3+ by the sorbent, respectively. Effects of pH, eluent concentration and volume, ionic strength, buffer concentration, sample volume and interferences on the recovery of the metal ions were investigated. A 5-ml portion of 0.4 M HCl solution was sufficient for quantitative elution of the metal ions from 0.5 ml of the sorbent packed in a 6.5 mm i.d. glass column. Quantitative recoveries were obtained in a pH range 5.5-6.5 for all the analytes. The volumes to be concentrated exceeding 500 ml, ionic strengths as high as 0.5 mol l-1, and acetate buffer concentrations up to 0.3 mol l-1 for Zn2+ and 0.4 mol l-1 for Cu2+ and Fe3+ did not have any significant effect on the recoveries. The system tolerated relatively high concentrations of diverse ions. Preconcentration factors up to 100 and detection limits of 0.31, 0.16 and 1.73 μg l-1 were obtained for Cu2+, Zn2+ and Fe3+, respectively, for their determination by a flame AAS instrument. The method was successfully applied to the metal ion determinations in several river water samples with good accuracy.

Investigation of DNA binding and bioactivities of furan cored Schiff base Cu (II), Ni (II), and Co (III) complexes: Synthesis, characterization and spectroscopic properties

2021 ◽  
Author(s):  
Kadtala Venkateswarlu ◽  
Sreenu Daravath ◽  
Gali Ramesh ◽  
P. V. Anantha Lakshmi ◽  
Shivaraj
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Spectroscopic Properties

Transition metal complexes with Girard reagent-based ligands, Part I: Synthesis and crystal structure of the first cobalt(III) complexes with Schiff base derivative of Girard reagent

2004 ◽  
Vol 7 (12) ◽  
pp. 1264-1268 ◽  
Author(s):  
Ljiljana S. Vojinović ◽  
Vukadin M. Leovac ◽  
Sladjana B. Novaković ◽  
Goran A. Bogdanović ◽  
János J. Csanádi ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Synthesis And Crystal Structure ◽  
Base Derivative

Development of a novel Schiff base derivative for enhancing the anticancer potential of 5-aminolevulinic acid-based photodynamic therapy

2017 ◽  
Vol 20 ◽  
pp. 182-188
Author(s):  
Yusei Shinohara ◽  
Yoshio Endo ◽  
Chiaki Abe ◽  
Ikkyu Shiba ◽  
Masahiro Ishizuka ◽  
...  
Keyword(s):  
Schiff Base ◽  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Base Derivative

Novel Luminescent Schiff Base Derivative owing Azo Moiety for Ultra Selective and Sensitive Chemosensor of Fe 3+ Ions

Luminescence ◽  
2021 ◽  
Author(s):  
Krisfian Tata Aneka Priyangga ◽  
Yehezkiel Steven Kurniawan ◽  
Leny Yuliati ◽  
Bambang Purwono ◽  
Tutik Dwi Wahyuningsih ◽  
...  
Keyword(s):  
Schiff Base ◽  
Base Derivative
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