scholarly journals Differential Pattern of Interhemispheric Connections Between Homotopic Layer V Regions in the Forelimb Representation in Rat Barrel Field Cortex

2015 ◽  
Vol 298 (11) ◽  
pp. 1885-1902 ◽  
Author(s):  
Tina M. Decosta-Fortune ◽  
Cheng X. Li ◽  
Amy L. de Jongh Curry ◽  
Robert S. Waters
Keyword(s):  
Barrel Field ◽  
Differential Pattern ◽  
Layer V

Chronic Suppression of Activity in Barrel Field Cortex Downregulates Sensory Responses in Contralateral Barrel Field Cortex

2005 ◽  
Vol 94 (5) ◽  
pp. 3342-3356 ◽  
Author(s):  
Lu Li ◽  
V. Rema ◽  
Ford F. Ebner
Keyword(s):  
Barrel Cortex ◽  
Cortical Excitability ◽  
Single Cells ◽  
Cortical Function ◽  
Adult Rats ◽  
Strong Suppression ◽  
Barrel Field ◽  
Layer V ◽  
Sensory Responses ◽  
Prominent Response

Numerous lines of evidence indicate that neural information is exchanged between the cerebral hemispheres via the corpus callosum. Unilateral ablation lesions of barrel field cortex (BFC) in adult rats induce strong suppression of background and evoked activity in the contralateral barrel cortex and significantly delay the onset of experience-dependent plasticity. The present experiments were designed to clarify the basis for these interhemispheric effects. One possibility is that degenerative events, triggered by the lesion, degrade contralateral cortical function. Another hypothesis, alone or in combination with degeneration, is that the absence of interhemispheric activity after the lesion suppresses contralateral responsiveness. The latter hypothesis was tested by placing an Alzet minipump subcutaneously and connecting it via a delivery tube to a cannula implanted over BFC. The minipump released muscimol, a GABAA receptor agonist at a rate of 1 μl/h, onto one barrel field cortex for 7 days. Then with the pump still in place, single cells were recorded in the contralateral BFC under urethan anesthesia. The data show a ∼50% reduction in principal whisker responses (D2) compared with controls, with similar reductions in responses to the D1 and D3 surround whiskers. Despite these reductions, spontaneous firing is unaffected. Fast spiking units are more sensitive to muscimol application than regular spiking units in both the response magnitude and the center/surround ratio. Effects of muscimol are also layer specific. Layer II/III and layer IV neurons decrease their responses significantly, unlike layer V neurons that fail to show significant deficits. The results indicate that reduced activity in one hemisphere alters cortical excitability in the other hemisphere in a complex manner. Surprisingly, a prominent response decrement occurs in the short-latency (3–10 ms) component of principal whisker responses, suggesting that suppression may spread to neurons dominated by thalamocortical inputs after interhemispheric connections are inactivated. Bilateral neurological impairments have been described after unilateral stroke lesions in the clinical literature.

Differential modulatory effects of norepinephrine on synaptically driven responses of layer V barrel field cortical neurons

2000 ◽  
Vol 868 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Barry D. Waterhouse ◽  
Robert Mouradian ◽  
Francis M. Sessler ◽  
Rick C.S. Lin
Keyword(s):  
Cortical Neurons ◽  
Barrel Field ◽  
Layer V

Oligodendrocytes in Developing Hameter Cerebral Cortex

1976 ◽  
Vol 34 ◽  
pp. 126-127
Author(s):  
MB. Tank Buschmann
Keyword(s):  
Cerebral Cortex ◽  
Optic Nerve ◽  
Frontal Cortex ◽  
Osmium Tetroxide ◽  
Sodium Cacodylate Buffer ◽  
Sodium Cacodylate ◽  
Tissue Samples ◽  
Cacodylate Buffer ◽  
Layer V ◽  
Adult Hamster

Development of oligodendrocytes in rat corpus callosum was described as a sequential change in cytoplasmic density which progressed from light to medium to dark (1). In rat optic nerve, changes in cytoplasmic density were not observed, but significant changes in morphology occurred just prior to and during myelination (2). In our study, the ultrastructural development of oligodendrocytes was studied in newborn, 5-, 10-, 15-, 20-day and adult frontal cortex of the golden hamster (Mesocricetus auratus).Young and adult hamster brains were perfused with paraformaldehyde-glutaraldehyde in sodium cacodylate buffer at pH 7.3 according to the method of Peters (3). Tissue samples of layer V of the frontal cortex were post-fixed in 2% osmium tetroxide, dehydrated in acetone and embedded in Epon-Araldite resin.

Identification of Differentially Expressed Genes Using cDNA-AFLP During Six Days In Vitro Tuberization of Potato

Zuriat ◽  
2015 ◽  
Vol 14 (1) ◽  
Author(s):  
Nono Carsono ◽  
Christian Bachem
Keyword(s):  
Gene Expression ◽  
Developmental Process ◽  
Expression Patterns ◽  
Induction Medium ◽  
In Vitro Tuberization ◽  
Storage Organ ◽  
Developmentally Regulated ◽  
Study Gene Expression ◽  
Differential Pattern

Tuberization in potato is a complex developmental process resulting in the differentiation of stolon into the storage organ, tuber. During tuberization, change in gene expression has been known to occur. To study gene expression during tuberization over the time, in vitro tuberization system provides a suitable tool, due to its synchronous in tuber formation. An early six days axillary bud growing on tuber induction medium is a crucial development since a large number of genes change in their expression patterns during this period. In order to identify, isolate and sequencing the genes which displaying differential pattern between tuberizing and non-tuberizing potato explants during six days in vitro tuberization, cDNA-AFLP fingerprint, method for the visualization of gene expression using cDNA as template which is amplified to generate an RNA-fingerprinting, was used in this experiment. Seventeen primer combinations were chosen based on their expression profile from cDNA-AFLP fingerprint. Forty five TDFs (transcript derived fragment), which displayed differential expressions, were obtained. Tuberizing explants had much more TDFs, which developmentally regulated, than those from non tuberizing explants. Seven TDFs were isolated, cloned and then sequenced. One TDF did not find similarity in the current databases. The nucleotide sequence of TDF F showed best similarity to invertase ezymes from the databases. The homology of six TDFs with known sequences is discussed in this paper.

scholarly journals Eastern Europe’s “Transitional Industry”?: Deconstructing the Early Streletskian

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
R. Dinnis ◽  
A. Bessudnov ◽  
N. Reynolds ◽  
T. Devièse ◽  
A. Dudin ◽  
...  
Keyword(s):  
Modern Human ◽  
East European Plain ◽  
Upper Palaeolithic ◽  
Radiocarbon Dates ◽  
East European ◽  
Archaeological Material ◽  
Younger Age ◽  
Layer V ◽  
Precise Relationship ◽  
Early Upper

AbstractThe Streletskian is central to understanding the onset of the Upper Palaeolithic on the East European Plain. Early Streletskian assemblages are frequently seen as marking the Neanderthal-anatomically modern human (AMH) anthropological transition, as well as the Middle-to-Upper Palaeolithic archaeological transition. The age of key Streletskian assemblages, however, remains unclear, and there are outstanding questions over how they relate to Middle and Early Upper Palaeolithic facies. The three oldest Streletskian layers—Kostenki 1 Layer V, Kostenki 6 and Kostenki 12 Layer III—were excavated by A. N. Rogachev in the mid-20th century. Here, we re-examine these layers in light of problems noted during Rogachev’s campaigns and later excavations. Layer V in the northern part of Kostenki 1 is the most likely assemblage to be unmixed. A new radiocarbon date of 35,100 ± 500 BP (OxA- X-2717-21) for this assemblage agrees with Rogachev’s stratigraphic interpretation and contradicts later claims of a younger age. More ancient radiocarbon dates for Kostenki 1 Layer V are from areas lacking diagnostic Streletskian points. The Kostenki 6 assemblage’s stratigraphic context is extremely poor, but new radiocarbon dates are consistent with Rogachev’s view that the archaeological material was deposited prior to the CI tephra (i.e. >34.3 ka BP). Multiple lines of evidence indicate that Kostenki 12 Layer III contains material of different ages. Despite some uncertainty over the precise relationship between the dated sample and diagnostic lithic material, Kostenki 1 Layer V (North) therefore currently provides the best age estimate for an early Streletskian context. This age is younger than fully Upper Palaeolithic assemblages elsewhere at Kostenki. Other “Streletskian” assemblages and Streletskian points from younger contexts at Kostenki are briefly reviewed, with possible explanations for their chronostratigraphic distribution considered. We caution that the cultural taxon Streletskian should not be applied to assemblages based simply on the presence of bifacially worked artefacts.

Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex

Neuroscience ◽  
2017 ◽  
Vol 358 ◽  
pp. 13-27 ◽  
Author(s):  
Hajime Sato ◽  
Tsutomu Kawano ◽  
Dong Xu Yin ◽  
Takafumi Kato ◽  
Hiroki Toyoda
Keyword(s):  
Pyramidal Neurons ◽  
Insular Cortex ◽  
Synaptic Potentiation ◽  
Layer V
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