Combined Inhibition of Tumor Necrosis Factor α and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody

Bispecific Antibody ◽

Interleukin 17 ◽

Rheumatoid Arthritis Development ◽

Therapeutic Opportunity ◽

Factor Α ◽

Identification and Characterization of 4-[[4-(2-Butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a Novel Dual Tumor Necrosis Factor-α-Converting Enzyme/Matrix Metalloprotease Inhibitor for the Treatment of Rheumatoid Arthritis

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.103.059675 ◽

2004 ◽

Vol 309 (1) ◽

pp. 348-355 ◽

Cited By ~ 64

Author(s):

Yuhua Zhang ◽

Jun Xu ◽

Jeremy Levin ◽

Martin Hegen ◽

Guangde Li ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis ◽

Matrix Metalloprotease ◽

Converting Enzyme ◽

Metalloprotease Inhibitor ◽

Factor Α ◽

Identification And Characterization ◽

Remission of anti‐tumor necrosis factor‐α antibody‐induced palmoplantar pustulosis with the Janus kinase inhibitor baricitinib in a patient with rheumatoid arthritis

The Journal of Dermatology ◽

10.1111/1346-8138.15860 ◽

2021 ◽

Author(s):

Shinichi Imafuku ◽

Akira Maeyama

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Kinase Inhibitor ◽

Janus Kinase ◽

Palmoplantar Pustulosis ◽

Janus Kinase Inhibitor ◽

Factor Α ◽

Tumor necrosis factor α 5′-flanking region, tumor necrosis factor receptor II, and HLA–DRB1 polymorphisms in Japanese patients with rheumatoid arthritis

Arthritis & Rheumatism ◽

10.1002/1529-0131(200004)43:4<753::aid-anr5>3.0.co;2-o ◽

2000 ◽

Vol 43 (4) ◽

pp. 753 ◽

Cited By ~ 40

Author(s):

Tsukasa Shibue ◽

Naoyuki Tsuchiya ◽

Tae Komata ◽

Masaki Matsushita ◽

Michiko Shiota ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Receptor ◽

Japanese Patients ◽

Flanking Region ◽

Factor Α ◽

Anti-inflammatory drugs and tumor necrosis factor-α production from monocytes: role of transcription factor NF-κB and implication for rheumatoid arthritis therapy

European Journal of Pharmacology ◽

10.1016/j.ejphar.2004.07.101 ◽

2004 ◽

Vol 501 (1-3) ◽

pp. 199-208 ◽

Cited By ~ 28

Author(s):

Luisa Lavagno ◽

Gabriele Gunella ◽

Claudio Bardelli ◽

Simona Spina ◽

Luigia Grazia Fresu ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Transcription Factor ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Inflammatory Drugs ◽

Anti Inflammatory ◽

Factor Α ◽

Anti-tumor necrosis factor α therapy in rheumatoid arthritis: Hitting two birds with one stone?

Arthritis & Rheumatism ◽

10.1002/art.20406 ◽

2004 ◽

Vol 51 (3) ◽

pp. 309-310 ◽

Cited By ~ 4

Author(s):

Kenneth J. Warrington

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Factor Α ◽

Elevated levels of circulating tumor necrosis factor-α, interferon-γ, and interleukin-2 in systemic reactions induced by anti-CD4 therapy in patients with rheumatoid arthritis

Cytokine ◽

10.1016/1043-4666(91)90026-a ◽

1991 ◽

Vol 3 (3) ◽

pp. 266-267 ◽

Cited By ~ 10

Author(s):

Gerd Horneff ◽

Andreas Krause ◽

Frank Emmrich ◽

Gerd R. Burmester

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Interleukin 2 ◽

Interferon Γ ◽

Systemic Reactions ◽

Factor Α ◽

Extraarticular Manifestations of Rheumatoid Arthritis in Patients under Anti-tumor Necrosis Factor-α Treatment

The Journal of Rheumatology ◽

10.3899/jrheum.141273 ◽

2015 ◽

Vol 42 (6) ◽

pp. 1059-1059 ◽

Cited By ~ 3

Author(s):

CLAUDE BACHMEYER ◽

CHRISTOPHER REIN ◽

SOPHIE GEORGIN-LAVIALLE

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Factor Α ◽

Necrosis Factor ◽

Extraarticular Manifestations

Efficacy of costimulation blockade with abatacept in rheumatoid arthritis patients refractory to tumor necrosis factor-α inhibition

Current Rheumatology Reports ◽

10.1007/s11926-006-0066-7 ◽

2006 ◽

Vol 8 (5) ◽

pp. 367-367

Author(s):

Larry Moreland

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Costimulation Blockade ◽

Factor Α ◽

Purification and biologic characterization of a specific tumor necrosis factor α inhibitor

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)80161-2 ◽

1989 ◽

Vol 264 (20) ◽

pp. 11966-11973

Author(s):

P Seckinger ◽

S Isaaz ◽

J M Dayer

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Specific Tumor ◽

Factor Α ◽

Biologic Characterization ◽

Myostatin induces tumor necrosis factor‐α expression in rheumatoid arthritis synovial fibroblasts through the PI3K–Akt signaling pathway

Journal of Cellular Physiology ◽

10.1002/jcp.27665 ◽

2018 ◽

Vol 234 (6) ◽

pp. 9793-9801 ◽

Cited By ~ 8

Author(s):

Chen‐Ming Su ◽

Sung‐Lin Hu ◽

Yi Sun ◽

Jin Zhao ◽

Chengqian Dai ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Tumor Necrosis Factor ◽

Signaling Pathway ◽

Tumor Necrosis ◽

Synovial Fibroblasts ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Factor Α ◽