Determination of drug absorption rate in time-variant disposition by direct deconvolution using beta clearance correction and end-constrained non-parametric regression

2005 ◽  
Vol 26 (8) ◽  
pp. 353-370 ◽  
Author(s):  
S. Neelakantan ◽  
P. Veng-Pedersen
2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Sayyida Sayyida ◽  
Nurdody Zakki

Diversity of Indonesian Batik hanging area. One of the very well-known Indonesian batik is Batik Madura. Batik Madura has become a pride for Indonesia, especially for Madura. The purpose of the study is to model the Sumenep pride to Batik Madura and to see the level of risk or tendency of batik madura pride for the community group Sumenep. This research method uses a non parametric regression used a non-parametric regression because the dependent variable in this study is the variable Y are variables not normally distributed. The results of this study states that the level of risk of the village in Sumenep proud of batik is almost 5 times higher than the islands while people in this city who live in the district town at risk Sumenep proud of Batik Madura 8-fold compared to the archipelago. So it can be concluded that the city is much more proud of batik than those who reside in rural areas especially those who reside in the islands. This study uses data from 100 questionnaires were analyzed using logistic regression analysis. The conclusion of this study is the pride of the batik model as follows: Function logistic regression / logit function: g (x) = 0,074 + 1,568X4(1)+2,159X4(2 this is case the islands as a comparison, X4(1)  is the place to stay in the village and X4(2)  is the place to stay in town, so the Model Opportunities p(x) = EXP(g(x))/1+EXP(g(x)).  Hopes for further research is to conduct research on the development of batik in an integrated region, the need to be disseminated to potential areas of particular potential in Madura batik, especially for residents who reside in the Islands.Keywords: Pride, Batik, Sumenep.


1978 ◽  
Vol 54 (1) ◽  
pp. 93-97
Author(s):  
R. C. Smart ◽  
C. D. Holdsworth

1. A large-volume scintillation counter was used to measure calcium absorption from the ratio of forearm uptake of 47Ca after oral 47CaCl2 (administered with milk) to forearm uptake after intravenously administered 47CaCl2. 2. In some subjects serial measurements of both forearm uptake of 47Ca and blood 47Ca radioactivity were also recorded, and by using deconvolution both total calcium absorption and calcium absorption rate were determined. 3. The forearm ratio determination of 47Ca absorption correlated well with that obtained by deconvolution of either serial blood 47Ca or forearm 47Ca measurements provided that the forearm radioactivity measurements were made at least 8 h after the administrations of 47CaCl2. 4. Although the two deconvolution techniques gave similar estimates of total calcium absorption there were discrepancies between their measurements of calcium absorption rate. These discrepancies were reduced but not eliminated by the use of additional lead shielding around the Armac counter.


Polymers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 3811
Author(s):  
Iosif Sorin Fazakas-Anca ◽  
Arina Modrea ◽  
Sorin Vlase

This paper proposes a new method for calculating the monomer reactivity ratios for binary copolymerization based on the terminal model. The original optimization method involves a numerical integration algorithm and an optimization algorithm based on k-nearest neighbour non-parametric regression. The calculation method has been tested on simulated and experimental data sets, at low (<10%), medium (10–35%) and high conversions (>40%), yielding reactivity ratios in a good agreement with the usual methods such as intersection, Fineman–Ross, reverse Fineman–Ross, Kelen–Tüdös, extended Kelen–Tüdös and the error in variable method. The experimental data sets used in this comparative analysis are copolymerization of 2-(N-phthalimido) ethyl acrylate with 1-vinyl-2-pyrolidone for low conversion, copolymerization of isoprene with glycidyl methacrylate for medium conversion and copolymerization of N-isopropylacrylamide with N,N-dimethylacrylamide for high conversion. Also, the possibility to estimate experimental errors from a single experimental data set formed by n experimental data is shown.


1997 ◽  
Vol 24 (5) ◽  
pp. 559-572
Author(s):  
E. Ayuga Tellez ◽  
C. Ayuga Tellez ◽  
C. Gonzalez Garcia ◽  
E. Martinez Falero

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