Improving case ascertainment of a population-based birth defects registry in New York State using hospital discharge data

2005 ◽  
Vol 73 (10) ◽  
pp. 663-668 ◽  
Author(s):  
Ying Wang ◽  
Monica Sharpe-Stimac ◽  
Philip K. Cross ◽  
Charlotte M. Druschel ◽  
Syni-An Hwang
Keyword(s):  
New York ◽  
Hospital Discharge ◽  
Birth Defects ◽  
New York State ◽  
Population Based ◽  
Hospital Discharge Data ◽  
Discharge Data ◽  
York State ◽  
Case Ascertainment

Twenty-Five-Year survival of children with birth defects in New York State: A population-based study

2011 ◽  
Vol 91 (12) ◽  
pp. 995-1003 ◽  
Author(s):  
Ying Wang ◽  
Jiaqi Hu ◽  
Charlotte M. Druschel ◽  
Russell S. Kirby
Keyword(s):  
New York ◽  
Birth Defects ◽  
New York State ◽  
Population Based ◽  
Population Based Study ◽  
York State

scholarly journals The Incidence, Characteristics, and Outcomes of Community and Hospital-Associated S. aureus Disease in Fulton County, Georgia

2020 ◽  
Vol 41 (S1) ◽  
pp. s81-s82
Author(s):  
Andrew Webster ◽  
Scott Fridkin ◽  
Susan Ray
Keyword(s):  
Hospital Discharge ◽  
Population Based ◽  
Incidence Rates ◽  
Outcome Data ◽  
Hospital Discharge Data ◽  
Invasive Infection ◽  
Emerging Infections ◽  
Inpatient Hospitalization ◽  
Discharge Data ◽  
Total Treatment

Background: Due to reliance on hospital discharge data for case identification, the burden of noninvasive and community-acquired S. aureus disease is often underestimated. To determine the full burden of S. aureus infections, we utilized population-based surveillance in a large urban county. Methods: The Georgia Emerging Infections Program (GA EIP) conducted CDC-funded, population-based surveillance by finding cases of S. aureus infections in 8 counties around Atlanta in 2017. Cases were residents with S. aureus isolated from either a normally sterile site in a 30-day period (invasive cases) or another site in a 14-day period (noninvasive cases). Medical records (all invasive and 1:4 sample of noninvasive cases) among Fulton County residents were abstracted for clinical, treatment, and outcome data. Cases treated were mapped to standard therapeutic site codes. Noninvasive specimens were reviewed and attributed to an invasive case if both occurred within 2 weeks. Incidence rates were calculated using 2017 census population and using a weight-adjusted cohort to account for sampling. Results: In total, 1,186 noninvasive (1:4 sample) and 529 invasive cases of S. aureus in Fulton county were reviewed. Only 35 of 1,186 (2.9%) noninvasive cases were temporally linked to invasive cases, resulting in 5,133 cases after extrapolation (529 invasive, 4,604 noninvasive). All invasive cases and 3,776 of 4,604 noninvasive cases (82%) were treated (4,305 total). Treatment was highest in skin (90%) and abscess (97%), lowest in urine (62%) and sputum (60%), and consisted of antibacterial agents alone (65%) or in addition to drainage procedures (35%). Overall, 41% of all cases were hospitalized, 12% required ICU admission, and 2.7% died, almost exclusively with bloodstream and pulmonary infections. Attribution of noninvasive infection was most often outside healthcare settings (87%); only 341 (7.9%) were hospital-onset cases; however, 34% of cases had had healthcare exposure in the preceding year, most often inpatient hospitalization (75%) or recent surgery (35%). Estimated countywide incidence was 414 per 100,000 (130 for MRSA and 284 for MSSA), invasive infection was 50 per 100,000. Among treated cases, 57% were SSTI, and the proportion of cases caused by MRSA was ~33% but varied slightly by therapeutic site (Fig. 1). Conclusions: The incidence of treated S. aureus infection in our large urban county is estimated to be 414 per 100,000 persons, which exceeds previously estimated rates based on hospital discharge data. Only 12% of treated infections were invasive, and <1 in 10 were hospital onset. Also, two-thirds of treated disease cases were MSSA; most were SSTIs.Funding: Proprietary Organization: Pfizer.Disclosures: Scott Fridkin, consulting fee - vaccine industry (spouse).

scholarly journals Infertility treatment and autism risk using the Modified Checklist for Autism in Toddlers (M-CHAT)

2020 ◽  
Vol 35 (3) ◽  
pp. 684-693 ◽  
Author(s):  
S L Robinson ◽  
T Parikh ◽  
T Lin ◽  
E M Bell ◽  
E Heisler ◽  
...  
Keyword(s):  
New York ◽  
Study Design ◽  
Screening Tool ◽  
New York State ◽  
Population Based ◽  
Infertility Treatment ◽  
Autism Spectrum ◽  
Fertility Treatment ◽  
York State

Abstract STUDY QUESTION Are toddlers conceived by fertility treatment at higher risk of failing a screening tool for autism spectrum disorders (ASD) than toddlers not conceived by treatment? SUMMARY ANSWER Compared with children not conceived by infertility treatment, children conceived by any infertility treatment, ovulation induction with or without intrauterine insemination (OI/IUI), or assisted reproductive technologies (ART) appeared to have had higher odds of failing an ASD screening; however, results were inconclusive and need replication. WHAT IS KNOWN ALREADY Although most of the studies which have examined risk of ASD after ART show no association, the results are mixed. Thus, further studies are needed to clarify this association. STUDY DESIGN SIZE, DURATION The Upstate KIDS Study is a population-based, prospective cohort study of children born in New York State between 2008 and 2010. Children were screened for ASD using the Modified Checklist for Autism in Toddlers (M-CHAT) at ages 18 and 24 months. PARTICIPANTS/MATERIALS, SETTING, AND METHODS The New York State live-birth registry was used to identify newborns conceived with and without fertility treatment with a 1:3 ratio, frequency matched on region of birth. At 18 and 24 months, 3183 and 3063 mothers, respectively, completed the M-CHAT questionnaire. The current analysis included 2586 singletons and 1296 twins with M-CHAT information at 18 and/or 24 months. Multivariable logistic regression with generalized estimating equations (GEE) was used to estimate odds ratios (aOR) and 95% confidence intervals (CI) after adjustment for covariates such as maternal age, education and plurality. MAIN RESULTS AND THE ROLE OF CHANCE We found that 200 (5.2%) and 115 (3.0%) children failed the M-CHAT at 18 and 24 months, respectively. The associations between use of infertility treatment and failing the M-CHAT at 18 and/or 24 months were positive but inconclusive as they failed to exclude no association (18 months aOR 1.71, 95% CI: 0.81–3.61; 24 months aOR 1.78, 95% CI: 0.66–4.81; and both 18 and 24 months aOR 1.53, 95% CI: 0.78–2.99). The relationships between OI/IUI and ART with M-CHAT failure at 18 and/or 24 months were similar to those of using any fertility treatment. In vitro fertilization with intracytoplasmic sperm injection was not consistently positively or inversely associated with M-CHAT failure at each time point (18 months aOR 1.20, 95% CI: 0.51–2.83; 24 months aOR 0.93, 95% CI: 0.37–2.31; and both 18 and 24 months aOR 1.09, 95% CI: 0.50–2.60). LIMITATIONS REASONS FOR CAUTION The M-CHAT is a screening tool used for ASD risk assessment, and therefore, M-CHAT failure does not indicate ASD diagnosis. In addition, we did not have power to detect associations of small magnitude. Finally, non-response to follow-up may bias the results. WIDER IMPLICATIONS OF THE FINDINGS Despite lack of precision, the positive associations between ART and M-CHAT failure suggest that larger population-based studies with longer follow-up are needed. STUDY FUNDING/COMPETING INTEREST(S) Supported by the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD; contracts HHSN275201200005C, HHSN267200700019C). The sponsor played no role in the study design, data collection, data analysis or interpretation, writing of the manuscript or decision to submit the article for publication. There are no conflicts of interest to declare. TRIAL REGISTRATION NUMBER Not applicable.

scholarly journals Pilot study of population-based newborn screening for spinal muscular atrophy in New York state

2017 ◽  
Vol 20 (6) ◽  
pp. 608-613 ◽  
Author(s):  
Jennifer N Kraszewski ◽  
Denise M Kay ◽  
Colleen F Stevens ◽  
Carrie Koval ◽  
Bianca Haser ◽  
...  
Keyword(s):  
New York ◽  
Pilot Study ◽  
Spinal Muscular Atrophy ◽  
Newborn Screening ◽  
Muscular Atrophy ◽  
New York State ◽  
Population Based ◽  
York State

A population-based survey of sun lamp and tanning parlor use in New York State, 1990

1994 ◽  
Vol 31 (3) ◽  
pp. 510-512 ◽  
Author(s):  
Patricia P. Lillquist ◽  
Mark S. Baptiste ◽  
Melissa A. Witzigman ◽  
Philip C. Nasca
Keyword(s):  
New York ◽  
New York State ◽  
Population Based ◽  
York State ◽  
Population Based Survey

scholarly journals Use and risks of surgical mesh for pelvic organ prolapse surgery in women in New York state: population based cohort study

BMJ ◽  
2015 ◽  
Vol 350 (jun02 1) ◽  
pp. h2685-h2685 ◽  
Author(s):  
B. Chughtai ◽  
J. Mao ◽  
J. Buck ◽  
S. Kaplan ◽  
A. Sedrakyan
Keyword(s):  
New York ◽  
Cohort Study ◽  
Pelvic Organ Prolapse ◽  
Surgical Mesh ◽  
New York State ◽  
Pelvic Organ ◽  
Population Based ◽  
Prolapse Surgery ◽  
York State ◽  
State Population

The New York Angler Cohort Study: Exposure Characterization and Reproductive and Developmental Health

1996 ◽  
Vol 12 (3-4) ◽  
pp. 327-334 ◽  
Author(s):  
John E. Vena ◽  
Germaine M. Buck ◽  
Paul Kostyniak ◽  
Pauline Mendola ◽  
Edward Fitzgerald ◽  
...  
Keyword(s):  
New York ◽  
Breast Milk ◽  
New York State ◽  
Population Based ◽  
York State ◽  
Entire Cohort ◽  
Telephone Interviews ◽  
Current Consumption ◽  
Other Substances ◽  
Developmental Health

The New York State Angler Study will evaluate the association between past and current consumption of contaminated fish from Lake Ontario and both short- and long-term health effects in a population-based cohort. It will measure fish consumption and reproductive and developmental health among 10,518 male anglers and 6,651 of their wives or partners, as well as among 913 female anglers. To characterize exposure among subgroups of the cohort, further analytical methods were developed and implemented to measure specific polychlorinated biphenyls (PCB) congeners, methylmercury, and other substances in biological samples. Exposure assessment has been completed for a stratified random sample of 321 anglers. In addition, analyses for 79 congeners of PCBs are complete for 177 anglers. A special study of duck andturtle consumers currently is underway. Telephone interviews have been completed with 2,454 of the 2,999 women who planned a pregnancy between 1991 and 1994. The entire cohort of male anglers, partners of male anglers, and female anglers has been submitted for matching with the New York State live birth and fetal death registries to obtain lifetime reproductive histories. A medical record abstraction study will assess perinatal and developmental outcomes among the 3,442 births that occurred between 1986 and 1991. Finally, a study of breast milk from currently lactating women is underway, and 215 breast milk samples have been collected from the planned pregnancy subcohort. Progress on each of the study components is discussed herein.

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