Circular RNA‐0072309 has antitumor influences in Hep3B cell line by targeting microRNA‐665

BioFactors ◽  
2020 ◽  
Author(s):  
Qiuyun Yu ◽  
Jinhua Dai ◽  
Ming Shu
Keyword(s):  
Cell Line ◽  
Circular Rna ◽  
Hep3b Cell

Apoptotic and anti-proliferative effects of 17β-estradiol and 17β-estradiol-like compounds in the Hep3B cell line

2006 ◽  
Vol 290 (1-2) ◽  
pp. 1-7 ◽  
Author(s):  
Erh-Jung Huang ◽  
Cheng-Chung Wu ◽  
Hsien-Ping Huang ◽  
Jer-Yuh Liu ◽  
Chung-Sheng Lin ◽  
...  
Keyword(s):  
Cell Line ◽  
Hep3b Cell ◽  
17Β Estradiol

scholarly journals Augmentation of haptoglobin production in Hep3B cell line by a nuclear factor NF-IL6

FEBS Letters ◽  
1991 ◽  
Vol 291 (1) ◽  
pp. 58-62 ◽  
Author(s):  
Shunji Natsuka ◽  
Hiroshi Isshiki ◽  
Shizuo Akira ◽  
Tadamitsu Kishimoto
Keyword(s):  
Cell Line ◽  
Hep3b Cell ◽  
Nuclear Factor

Anti-proliferative and apoptosis-triggering potential of disulfiram and disulfiram-loaded polysorbate 80-stabilized PLGA nanoparticles on hepatocellular carcinoma Hep3B cell line

2016 ◽  
Vol 12 (6) ◽  
pp. 1641-1650 ◽  
Author(s):  
Muddasarul Hoda ◽  
Sankar Pajaniradje ◽  
Garima Shakya ◽  
Kumaravel Mohankumar ◽  
Rukkumani Rajagopalan
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Line ◽  
Plga Nanoparticles ◽  
Hep3b Cell ◽  
Polysorbate 80

Retinoic Acid Differentially Regulates Retinoic Acid Receptor-Mediated Pathways in the HEP3B Cell Line

1998 ◽  
Vol 238 (1) ◽  
pp. 241-247 ◽  
Author(s):  
Yu-Jui Yvonne Wan ◽  
Yan Cai ◽  
Thomas R. Magee
Keyword(s):  
Retinoic Acid ◽  
Cell Line ◽  
Retinoic Acid Receptor ◽  
Hep3b Cell ◽  
Acid Receptor

Circular RNA 0039411 Is Involved in Neodymium Oxide-induced Inflammation and Antiproliferation in a Human Bronchial Epithelial Cell Line via Sponging miR-93-5p

2019 ◽  
Vol 170 (1) ◽  
pp. 69-81 ◽  
Author(s):  
Qiuhan Hua ◽  
Yingnan Chen ◽  
Yufei Liu ◽  
Meizhen Li ◽  
Qinqin Diao ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Line ◽  
Neodymium Oxide ◽  
Circular Rna ◽  
Bronchial Epithelial Cell ◽  
Human Bronchial Epithelial Cell ◽  
Epithelial Cell Line ◽  
Bronchial Epithelial

scholarly journals CircMiner: accurate and rapid detection of circular RNA through splice-aware pseudo-alignment scheme

2020 ◽  
Vol 36 (12) ◽  
pp. 3703-3711 ◽  
Author(s):  
Hossein Asghari ◽  
Yen-Yi Lin ◽  
Yang Xu ◽  
Ehsan Haghshenas ◽  
Colin C Collins ◽  
...  
Keyword(s):  
Cell Line ◽  
Rapid Detection ◽  
High Throughput Sequencing ◽  
Circular Rna ◽  
Supplementary Information ◽  
Circular Rnas ◽  
Alignment Technique ◽  
Nucleotide Resolution ◽  
High Degree ◽  
Splice Junctions

Abstract Motivation The ubiquitous abundance of circular RNAs (circRNAs) has been revealed by performing high-throughput sequencing in a variety of eukaryotes. circRNAs are related to some diseases, such as cancer in which they act as oncogenes or tumor-suppressors and, therefore, have the potential to be used as biomarkers or therapeutic targets. Accurate and rapid detection of circRNAs from short reads remains computationally challenging. This is due to the fact that identifying chimeric reads, which is essential for finding back-splice junctions, is a complex process. The sensitivity of discovery methods, to a high degree, relies on the underlying mapper that is used for finding chimeric reads. Furthermore, all the available circRNA discovery pipelines are resource intensive. Results We introduce CircMiner, a novel stand-alone circRNA detection method that rapidly identifies and filters out linear RNA sequencing reads and detects back-splice junctions. CircMiner employs a rapid pseudo-alignment technique to identify linear reads that originate from transcripts, genes or the genome. CircMiner further processes the remaining reads to identify the back-splice junctions and detect circRNAs with single-nucleotide resolution. We evaluated the efficacy of CircMiner using simulated datasets generated from known back-splice junctions and showed that CircMiner has superior accuracy and speed compared to the existing circRNA detection tools. Additionally, on two RNase R treated cell line datasets, CircMiner was able to detect most of consistent, high confidence circRNAs compared to untreated samples of the same cell line. Availability and implementation CircMiner is implemented in C++ and is available online at https://github.com/vpc-ccg/circminer. Supplementary information Supplementary data are available at Bioinformatics online.

scholarly journals Curcumin Induces p53-Null Hepatoma Cell Line Hep3B Apoptosis through the AKT-PTEN-FOXO4 Pathway

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
An-Ting Liou ◽  
Mei-Fang Chen ◽  
Chu-Wen Yang
Keyword(s):  
Cancer Cells ◽  
Cell Line ◽  
Cell Apoptosis ◽  
Hepatoma Cell ◽  
Hep3b Cell ◽  
Hepatoma Cell Line ◽  
Potential Candidate ◽  
Curcumin Treatment ◽  
Liver Cancers ◽  
Hep3b Cells

Objective. Curcumin (diferuloylmethane) is a yellow-colored polyphenol with antiproliferative and proapoptotic activities to various types of cancer cells. This study explored the mechanism by which curcumin induces p53-null hepatoma cell apoptosis. Results. AKT, FOXO1, and FOXO3 proteins were downregulated after curcumin treatment. Conversely, PTEN was upregulated. Subcellular fractionations revealed that the FOXO4 protein translocated from cytosol into the nucleus after curcumin treatment. Overexpression of FOXO4 increases the sensitivity of Hep3B cells to curcumin. Knockdown of the FOXO4 gene by siRNA inhibits the proapoptotic effects of curcumin on Hep3B cell. Conclusions. This study revealed the AKT/PTEN/FOXO4 pathway as a potential candidate of target for treatment of p53-null liver cancers.

scholarly journals Apoptosis Induction in Hep3B cell line by Lu‐Do‐Huang

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Jo‐Hsuan Yang ◽  
Ting‐Yi Chien ◽  
Chun‐Han Tsai ◽  
Hui‐Yu Huang
Keyword(s):  
Cell Line ◽  
Hep3b Cell ◽  
Apoptosis Induction

Comparative Proteomic Analysis of Drug Sodium Iron Chlorophyllin Addition to Hep3B Cell Line

2008 ◽  
Vol S2 (01) ◽  
pp. 180-180
Author(s):  
H. Jin ◽  
Y. Chen ◽  
F. Yang ◽  
L. Zhang ◽  
G. Yan ◽  
...  
Keyword(s):  
Cell Line ◽  
Proteomic Analysis ◽  
Hep3b Cell ◽  
Comparative Proteomic Analysis

scholarly journals Inhibitory effects of genistein in combination with gefitinib on the hepatocellular carcinoma Hep3B cell line

2019 ◽  
Author(s):  
Yongxi Tong ◽  
Mingshan Wang ◽  
Haijun Huang ◽  
Jiajie Zhang ◽  
Yicheng Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Line ◽  
Hep3b Cell ◽  
Inhibitory Effects
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