Reconstruction of tricarboxylic acid cycle inCorynebacterium glutamicumwith a genome-scale metabolic network model fortrans-4-hydroxyproline production

2018 ◽  
Vol 116 (1) ◽  
pp. 99-109 ◽  
Author(s):  
Yu Zhang ◽  
Yun Zhang ◽  
Xiuling Shang ◽  
Bo Wang ◽  
Qitiao Hu ◽  
...  
Keyword(s):  
Metabolic Network ◽  
Network Model ◽  
Tricarboxylic Acid Cycle ◽  
Tricarboxylic Acid ◽  
Acid Cycle ◽  
Metabolic Network Model ◽  
A Genome ◽  
Genome Scale

scholarly journals Generation and Evaluation of a Genome-Scale Metabolic Network Model of Synechococcus elongatus PCC7942

Metabolites ◽  
2014 ◽  
Vol 4 (3) ◽  
pp. 680-698 ◽  
Author(s):  
Julián Triana ◽  
Arnau Montagud ◽  
Maria Siurana ◽  
David Fuente ◽  
Arantxa Urchueguía ◽  
...  
Keyword(s):  
Metabolic Network ◽  
Network Model ◽  
Synechococcus Elongatus ◽  
Metabolic Network Model ◽  
Synechococcus Elongatus Pcc7942 ◽  
A Genome ◽  
Genome Scale

scholarly journals Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model

2010 ◽  
Vol 26 (12) ◽  
pp. i255-i260 ◽  
Author(s):  
K. Yizhak ◽  
T. Benyamini ◽  
W. Liebermeister ◽  
E. Ruppin ◽  
T. Shlomi
Keyword(s):  
Metabolic Network ◽  
Network Model ◽  
Quantitative Proteomics ◽  
Metabolic Network Model ◽  
A Genome ◽  
Genome Scale

Reconstruction and analysis of a genome-scale metabolic model for Eriocheir sinensis eyestalks

2016 ◽  
Vol 12 (1) ◽  
pp. 246-252 ◽  
Author(s):  
Bin Wang ◽  
Qianji Ning ◽  
Tong Hao ◽  
Ailing Yu ◽  
Jinsheng Sun
Keyword(s):  
Metabolic Network ◽  
Network Model ◽  
Transcriptome Sequencing ◽  
Metabolic Model ◽  
Eriocheir Sinensis ◽  
Metabolic Network Model ◽  
A Genome ◽  
Genome Scale

We reconstructed a metabolic network model for E. sinensis eyestalks based on transcriptome sequencing which contains 1304 reactions, 1381 unigenes and 1243 metabolites distributing in 98 pathways.

scholarly journals Improvement of l-arginine production by in silico genome-scale metabolic network model guided genetic engineering

3 Biotech ◽  
2020 ◽  
Vol 10 (3) ◽  
Author(s):  
Mingzhu Huang ◽  
Yue Zhao ◽  
Rong Li ◽  
Weihua Huang ◽  
Xuelan Chen
Keyword(s):  
Genetic Engineering ◽  
Metabolic Network ◽  
Network Model ◽  
In Silico ◽  
Metabolic Network Model ◽  
Genome Scale

IN SILICO GENOME-SCALE RECONSTRUCTION AND ANALYSIS OF THE SHEWANELLA LOIHICA PV-4 METABOLIC NETWORK

2018 ◽  
Vol 26 (03) ◽  
pp. 373-397
Author(s):  
ZIXIANG XU ◽  
JING GUO ◽  
YUNXIA YUE ◽  
JING MENG ◽  
XIAO SUN
Keyword(s):  
Metabolic Network ◽  
Network Model ◽  
Microbial Fuel Cells ◽  
Metabolic Networks ◽  
Acid Metabolism ◽  
Electricity Production ◽  
Nucleic Acid Metabolism ◽  
Exchange Reactions ◽  
A Genome ◽  
Genome Scale

Microbial Fuel Cells (MFCs) are devices that generate electricity directly from organic compounds with microbes (electricigens) serving as anodic catalysts. As a novel environment-friendly energy source, MFCs have extensive practical value. Since the biological features and metabolic mechanism of electricigens have a great effect on the electricity production of MFCs, it is a big deal to screen strains with high electricity productivity for improving the power output of MFC. Reconstructions and simulations of metabolic networks are of significant help in studying the metabolism of microorganisms so as to guide gene engineering and metabolic engineering to improve their power-generating efficiency. Herein, we reconstructed a genome-scale constraint-based metabolic network model of Shewanella loihica PV-4, an important electricigen, based on its genomic functional annotations, reaction databases and published metabolic network models of seven microorganisms. The resulting network model iGX790 consists of 902 reactions (including 71 exchange reactions), 798 metabolites and 790 genes, covering the main pathways such as carbon metabolism, energy metabolism, amino acid metabolism, nucleic acid metabolism and lipid metabolism. Using the model, we simulated the growth rate, the maximal synthetic rate of ATP, the flux variability analysis of metabolic network, gene deletion and so on to examine the metabolism of S. loihica PV-4.

scholarly journals The Tricarboxylic Acid Cycle, an Ancient Metabolic Network with a Novel Twist

PLoS ONE ◽  
2007 ◽  
Vol 2 (8) ◽  
pp. e690 ◽  
Author(s):  
Ryan J. Mailloux ◽  
Robin Bériault ◽  
Joseph Lemire ◽  
Ranji Singh ◽  
Daniel R. Chénier ◽  
...  
Keyword(s):  
Metabolic Network ◽  
Tricarboxylic Acid Cycle ◽  
Tricarboxylic Acid ◽  
Acid Cycle

Applications of genome-scale metabolic network model in metabolic engineering

2014 ◽  
Vol 42 (3) ◽  
pp. 339-348 ◽  
Author(s):  
Byoungjin Kim ◽  
Won Jun Kim ◽  
Dong In Kim ◽  
Sang Yup Lee
Keyword(s):  
Metabolic Engineering ◽  
Metabolic Network ◽  
Network Model ◽  
Metabolic Network Model ◽  
Genome Scale
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