Destruction of the bundle of His abolished bigeminal rhythms produced by adrenaline in thiopentone–cyclopropane anesthetized dogs. Bigeminal rhythms were still elicited, however, after selective destruction of the A–V node. Destruction of the bundle of His did not prevent multifocal arrhythmias but did increase the dose of adrenaline required to induce them. Multifocal arrhythmias produced after destruction of the bundle of His were abolished by injections of acetylcholine into the left anterior descending, but not the circumflex coronary artery, results opposite to those obtained in normal hearts.
Swine Atrioventricular Node Ablation Using Stereotactic Radiosurgery: Methods and In Vivo Feasibility Investigation for Catheter‐Free Ablation of Cardiac Arrhythmias