Development of a sensitive and rapid UHPLC–MS/MS method for simultaneous quantification of nine compounds in rat plasma and application in a comparative pharmacokinetic study after oral administration of Xuefu Zhuyu Decoction and nimodipine

Chunyan Fu; Qian Wu; Zhimin Zhang; Zian Xia; Zhaoying Liu; Hongmei Lu; Yang Wang; Gang Huang

doi:10.1002/bmc.4872

Development of a sensitive and rapid UHPLC–MS/MS method for simultaneous quantification of nine compounds in rat plasma and application in a comparative pharmacokinetic study after oral administration of Xuefu Zhuyu Decoction and nimodipine

Biomedical Chromatography ◽

10.1002/bmc.4872 ◽

2020 ◽

Vol 34 (9) ◽

Author(s):

Chunyan Fu ◽

Qian Wu ◽

Zhimin Zhang ◽

Zian Xia ◽

Zhaoying Liu ◽

...

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Comparative Pharmacokinetic ◽

Simultaneous Quantification ◽

Xuefu Zhuyu Decoction

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Validated UPLC-MS/MS method for simultaneous quantification of eight saikosaponins in rat plasma: Application to a comparative pharmacokinetic study in depression rats after oral administration of extracts of raw and vinegar-baked Bupleuri Radix

Journal of Chromatography B ◽

10.1016/j.jchromb.2017.06.007 ◽

2017 ◽

Vol 1060 ◽

pp. 231-239 ◽

Cited By ~ 19

Author(s):

Tianli Lei ◽

Dandan Zhang ◽

Kun Guo ◽

Mingxiao Li ◽

Chongning Lv ◽

...

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Comparative Pharmacokinetic ◽

Simultaneous Quantification ◽

Bupleuri Radix

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Validated LC-MS method for simultaneous quantitation of catalpol and harpagide in rat plasma: application to a comparative pharmacokinetic study in normal and diabetic rats after oral administration of Zeng-Ye-Decoction

Biomedical Chromatography ◽

10.1002/bmc.2949 ◽

2013 ◽

Vol 27 (11) ◽

pp. 1503-1510 ◽

Cited By ~ 16

Author(s):

Yukun Feng ◽

Zhenzhen Liu ◽

Ying Peng ◽

Lunhui Zhang ◽

Ping Ju ◽

...

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Diabetic Rats ◽

Comparative Pharmacokinetic

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Using UPLC-MS/MS for Characterization of Active Components in Extracts of Yupingfeng and Application to a Comparative Pharmacokinetic Study in Rat Plasma after Oral Administration

Molecules ◽

10.3390/molecules22050810 ◽

2017 ◽

Vol 22 (5) ◽

pp. 810 ◽

Cited By ~ 11

Author(s):

Meng-Qi Jia ◽

Ye-Juan Xiong ◽

Yun Xue ◽

Yan Wang ◽

Chao Yan

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Active Components ◽

Comparative Pharmacokinetic

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Simultaneous quantification of multiple components in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Huangqi decoction

Biomedical Chromatography ◽

10.1002/bmc.4178 ◽

2018 ◽

Vol 32 (5) ◽

pp. e4178 ◽

Cited By ~ 9

Author(s):

Jia-Kai Zeng ◽

Yuan-Yuan Li ◽

Tian-Ming Wang ◽

Jie Zhong ◽

Jia-Sheng Wu ◽

...

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Simultaneous Quantification ◽

Multiple Components

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Development and validation of a UHPLC-MS/MS method for the simultaneous determination of five bioactive flavonoids in rat plasma and comparative pharmacokinetic study after oral administration of Xiaochaihu Tang and three compatibilities

Journal of Separation Science ◽

10.1002/jssc.201601420 ◽

2017 ◽

Vol 40 (9) ◽

pp. 1896-1905 ◽

Cited By ~ 6

Author(s):

Yunhai Bo ◽

Lijuan Wang ◽

Xiao Wu ◽

Longshan Zhao ◽

Jingyu Yang ◽

...

Keyword(s):

Oral Administration ◽

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Comparative Pharmacokinetic ◽

Development And Validation

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A simple liquid chromatography coupled with tandem mass spectrometry approach for the simultaneous quantification of thirteen compounds in rats following oral administration of raw and processed Fructus Xanthii : Application in a comparative pharmacokinetic study

Journal of Separation Science ◽

10.1002/jssc.201900506 ◽

2019 ◽

Vol 42 (22) ◽

pp. 3403-3412 ◽

Cited By ~ 3

Author(s):

Hai Jiang ◽

Liu Yang ◽

Xudong Xing ◽

Meiling Yan ◽

Xinyue Guo ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Oral Administration ◽

Pharmacokinetic Study ◽

Simple Liquid ◽

Tandem Mass ◽

Comparative Pharmacokinetic ◽

Simultaneous Quantification

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Comparative pharmacokinetic study of two boswellic acids in normal and arthritic rat plasma after oral administration ofBoswellia serrataextract or Huo Luo Xiao Ling Dan by LC-MS

Biomedical Chromatography ◽

10.1002/bmc.3182 ◽

2014 ◽

Vol 28 (10) ◽

pp. 1402-1408 ◽

Cited By ~ 16

Author(s):

Hui Wang ◽

Chenning Zhang ◽

Yun Wu ◽

Yu Ai ◽

David Y.-W. Lee ◽

...

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Comparative Pharmacokinetic ◽

Boswellic Acids

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Simultaneous quantification of atractyloside and carboxyatractyloside in rat plasma by LC‐MS/MS: Application to a pharmacokinetic study after oral administration of Xanthii Fructus extract

Journal of Separation Science ◽

10.1002/jssc.201900888 ◽

2019 ◽

Vol 43 (3) ◽

pp. 590-597

Author(s):

Hong Pan ◽

Feng Yang ◽

Daiyuan Xiang ◽

Fuguo Shi

Keyword(s):

Oral Administration ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Simultaneous Quantification

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A comparative pharmacokinetic study of three flavonoids and three anthraquinones in normal and gastrointestinal motility disorders rat plasma after the oral administration of Wei-Chang-Shu tablet using high-performance liquid chromatography-tandem mass sp

Biomedical Chromatography ◽

10.1002/bmc.3997 ◽

2017 ◽

Vol 31 (11) ◽

pp. e3997 ◽

Cited By ~ 1

Author(s):

Yan Ren ◽

Weiwei Zhao ◽

Juanjuan Zhao ◽

Xiangming Chen ◽

Chen Yu ◽

...

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Oral Administration ◽

Gastrointestinal Motility ◽

Pharmacokinetic Study ◽

High Performance ◽

Rat Plasma ◽

Tandem Mass ◽

Comparative Pharmacokinetic ◽

Liquid Chromatography Tandem Mass

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Simultaneous determination of senkyunolide I and senkyunolide H in rat plasma by LC-MS: application to a comparative pharmacokinetic study in normal and migrainous rats after oral administration of Chuanxiong Rhizoma extract

Biomedical Chromatography ◽

10.1002/bmc.3420 ◽

2015 ◽

Vol 29 (9) ◽

pp. 1297-1303 ◽

Cited By ~ 7

Author(s):

Xu Zhao ◽

Tiancheng Ma ◽

Chenning Zhang ◽

Shaohuai Shi ◽

Sijiao Cui ◽

...

Keyword(s):

Oral Administration ◽

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Comparative Pharmacokinetic ◽

Senkyunolide I

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