For preterm infants with evolving or established bronchopulmonary dysplasia (BPD), what are the effects of late (≥ 7 days) systemic corticosteroids (CSs)?

2021 ◽  
Author(s):  
Jane Burch ◽  
Yanina Sguassero
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Systemic Corticosteroids

An Update on the Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk of Bronchopulmonary Dysplasia

2014 ◽  
Vol 165 (6) ◽  
pp. 1258-1260 ◽  
Author(s):  
Lex W. Doyle ◽  
Henry L. Halliday ◽  
Richard A. Ehrenkranz ◽  
Peter G. Davis ◽  
John C. Sinclair
Keyword(s):  
Cerebral Palsy ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Effect Modification ◽  
Systemic Corticosteroids ◽  
The Impact

Fluid status in the first 10 days of life and death/bronchopulmonary dysplasia among preterm infants

2021 ◽  
Author(s):  
Safiya Soullane ◽  
Sharina Patel ◽  
Martine Claveau ◽  
Laila Wazneh ◽  
Guilherme Sant’Anna ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Life And Death ◽  
Fluid Status

scholarly journals Stem cells for bronchopulmonary dysplasia in preterm infants: A randomized controlled phase II trial

2021 ◽  
Author(s):  
So Yoon Ahn ◽  
Yun Sil Chang ◽  
Myung Hee Lee ◽  
Se In Sung ◽  
Byong Sop Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Phase Ii ◽  
Phase Ii Trial ◽  
Randomized Controlled

Characterization of lung ultrasound imaging in preterm infants with bronchopulmonary dysplasia

2021 ◽  
pp. 1-13
Author(s):  
Ying-Hua Sun ◽  
Lin Yuan ◽  
Yang Du ◽  
Jian-Guo Zhou ◽  
Sam Bill Lin ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Neonatal Intensive Care ◽  
Lung Ultrasound ◽  
Imaging Method ◽  
Chronic Lung Diseases ◽  
Pleural Line ◽  
Ultrasound Features

BACKGROUND: Lung ultrasound (LUS) is a bedside technique that can be used on diagnosis and follow-up of neonatal respiratory diseases. However, there are rare reports on the ultrasound features of bronchopulmonary dysplasia (BPD) which is one of the most common chronic lung diseases in preterm infants. OBJECTIVE: To describe the ultrasound features of different BPD levels, and to investigate the value of ultrasound in evaluating moderate-to-severe BPD. METHODS: In this prospective cohort study, newborns of less than 37 weeks’ gestational age in neonatal intensive care unit (NICU) were included. The LUS characteristics including pleural line, alveolar-interstitial syndrome (AIS), retrodiaphragmatic hyperechogenicity and diaphragmatic morphology were observed and recorded. The reliability of LUS in evaluating moderate and severe BPD were compared and calculated. RESULTS: A total of 108 infants were enrolled in our study: 39, 24, 29, 16 infants had non, mild, moderate and severe BPD. The median(IQR) pleura thickness in the moderate-to-severe BPD group was 1.7(1.6–1.85) mm, which was thicker than that in the none-to-mild BPD infants (P <  0.001), meanwhile the proportions of rough pleural lines, diffuse AIS, retrodiaphragmatic hyperechogenicity, small cysts above the diaphragm and rough diaphragm in the moderate-to-severe BPD group were also higher than those in none-to-mild BPD group (86.7% vs 36.5, 57.8% vs 7.9%, 37.8% vs 0, 33.3% vs 0, P <  0.001). In evaluating moderate-to-severe BPD, rough pleura had 91.1% (95% confidence interval [CI]: 0.793–0.965) in sensitivity, 91.3% (95% CI: 0.797–0.966) in negative predictive value (NPV), and 66.7% (95% CI: 0.544–0.771) in specificity. Small cysts had 100% (95% CI: 0.941-1) in specificity, 100% (95% CI: 0.816-1) in PPV, and 37.8% in sensitivity (95% CI: 0.251–0.524). Rough diaphragm had 100% (95% CI: 0.943-1) in sensitivity, 100% (95% CI: 0.796-1) in PPV and 33.3% (95% CI: 0.211–0.478) in specificity. CONCLUSIONS: Depending on its unique advantages such as convenient, no radiation and repeatable, LUS is a valuable imaging method in assessing the severity of BPD, especially in moderate and severe BPD.

scholarly journals Antenatal exposure to Ureaplasma species exacerbates bronchopulmonary dysplasia synergistically with subsequent prolonged mechanical ventilation in preterm infants

2012 ◽  
Vol 71 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Tadashi Inatomi ◽  
Shinya Oue ◽  
Tohru Ogihara ◽  
Seigo Hira ◽  
Masashi Hasegawa ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Prolonged Mechanical Ventilation
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