Culprit plaque characteristics in younger versus older patients with acute coronary syndromes: An optical coherence tomography study from the FORMIDABLE registry

2017 ◽  
Vol 92 (1) ◽  
pp. E1-E8 ◽  
Author(s):  
Umberto Barbero ◽  
Paolo Scacciatella ◽  
Mario Iannaccone ◽  
Fabrizio D'Ascenzo ◽  
Giampaolo Niccoli ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Acute Coronary Syndromes ◽  
Older Patients ◽  
Optical Coherence ◽  
Coronary Syndromes

scholarly journals Optical Coherence Tomography Analysis of Attenuated Plaques Detected by Intravascular Ultrasound in Patients with Acute Coronary Syndromes

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Takashi Kubo ◽  
Yoshiki Matsuo ◽  
Yasushi Ino ◽  
Takashi Tanimoto ◽  
Kohei Ishibashi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intravascular Ultrasound ◽  
Acute Coronary Syndromes ◽  
Plaque Rupture ◽  
Optical Coherence ◽  
Coronary Syndrome ◽  
Ultrasound Attenuation ◽  
Coronary Syndromes ◽  
Tomography Analysis ◽  
Important Marker

Background. Recent intravascular ultrasound (IVUS) studies have demonstrated that hypoechoic plaque with deep ultrasound attenuation despite absence of bright calcium is common in acute coronary syndrome. Such “attenuated plaque” may be an IVUS characteristic of unstable lesion.Methods. We used optical coherence tomography (OCT) in 104 patients with unstable angina to compare lesion characteristics between IVUS-detected attenuated plaque and nonattenuated plaque.Results. IVUS-detected attenuated plaque was observed in 41 (39%) patients. OCT-detected lipidic plaque (88% versus 49%, ), thin-cap fibroatheroma (48% versus 16%, ), plaque rupture (44% versus 11%, ), and intracoronary thrombus (54% versus 17%, ) were more often seen in IVUS-detected attenuated plaques compared with nonattenuated plaques.Conclusions. IVUS-detected attenuated plaque has many characteristics of unstable coronary lesion. The presence of attended plaque might be an important marker of lesion instability.

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