Background: The presence of comorbidities and relative immunosuppression in chronic kidney disease patients on
hemodialysis raises concerns that these patients may have an increased risk of severe COVID-19. We aimed to examine
the presentation and in-hospital outcomes of COVID-19 patients with end stage renal disease requiring hemodialysis.
Methods:To examine presentation and in-hospital outcomes of COVID-19 in patients with end stage renal disease requiring hemodialysis. The
study was conducted in a tertiary care centre from June 2020 to December 2020. We collected clinical & laboratory data of 126 COVID-19
positive in-patients requiring hemodialysis. CKD patients referred to our centre for hemodialysis patients were also included. Patients requiring
invasive ventilation and management in intensive care units were excluded. Patients were categorised into two groups based on their outcomes;
survivors and non-survivors. Detailed history & biochemistry results were recorded and analysed using SPSS 20.0.
Results: A total of 126 patients were included in our study, with male predominance, n=91(72.2%). The median age of our study population was
53 years. The main presenting complaints were fever, n=78(61.9%); cough, n=69(54.8%), dyspnea, n= 62(49.2%), fatigue, n=102(81%) and
myalgia, n=51(40.5%). Eighty nine(70.6%) patients were hypertensives, 48 (38.1%) known diabetics and 13 (10.3%) had pre-existing chronic
obstructive pulmonary disease. Lung involvement in CT imaging at the time of admission, were found in 93(85.5%) patients. On comparison
between survivor and non-survivors, there was no statistical difference in the biochemical prole, however there was signicant chest imaging
ndings (p<0.001) and requirement of ventilator (p<0.001) in the non-survivor group.
Conclusion: In our study, mortality was high in patients showing chest imaging ndings and also in those requiring non-invasive ventilation
even in non-intensive care setting, at admission. The high mortality in CKD patients on hemodialysis emphasizes the need of dedicated COVID
hemodialysis units,to prevent interruption in routine outpatient stable dialysis patients.
IN-HOSPITAL OUTCOMES OF TRANSCATHETER MITRAL VALVE REPLACEMENT IN PATIENTS WITH AND WITHOUT END STAGE RENAL DISEASE: A NATIONAL PROPENSITY MATCH STUDY
