A Peptide Nucleic Acid (PNA) Heteroduplex Probe Containing an Inosine-Cytosine Base Pair Discriminates a Single-Nucleotide Difference in RNA

2013 ◽  
Vol 19 (16) ◽  
pp. 5034-5040 ◽  
Author(s):  
Katsuhiko Matsumoto ◽  
Eiji Nakata ◽  
Tomoki Tamura ◽  
Isao Saito ◽  
Yasunori Aizawa ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Base Pair ◽  
Peptide Nucleic Acid ◽  
Nucleotide Difference ◽  
Single Nucleotide

Application of a lanthanide fluorescent chelate label for detection of single-nucleotide mutations with peptide nucleic acid probes

2006 ◽  
Vol 355 (2) ◽  
pp. 278-284 ◽  
Author(s):  
Kimikazu Hashino ◽  
Masahiro Ito ◽  
Keisuke Ikawa ◽  
Chihiro Hosoya ◽  
Takuya Nishioka ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Peptide Nucleic Acid ◽  
Single Nucleotide ◽  
Nucleic Acid Probes

Ultrasensitive SERS detection of highly homologous miRNAs by generating 3D organic-nanoclusters and a functionalized chip with locked nucleic acid probes

2018 ◽  
Vol 54 (95) ◽  
pp. 13431-13434 ◽  
Author(s):  
Mengting Zhu ◽  
Zhaomei Sun ◽  
Zhen Zhang ◽  
Shusheng Zhang
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid ◽  
Nucleotide Difference ◽  
Single Nucleotide ◽  
Nucleic Acid Probes ◽  
Sers Detection ◽  
New Finding

Herein, a new finding is reported that 3D organic-nanoclusters (3DONs) with superior SERS properties as an original reporter could accurately and sensitively distinguish microRNAs (miRNAs) with highly similar sequences, even with a single-nucleotide difference.

Combination of peptide nucleic acid beacon and nuclease S1 for clear-cut genotyping of single nucleotide polymorphisms

2007 ◽  
Vol 363 (2) ◽  
pp. 300-302 ◽  
Author(s):  
Sheng Ye ◽  
Yoshitaka Miyajima ◽  
Toshiyuki Ohnishi ◽  
Yoji Yamamoto ◽  
Makoto Komiyama
Keyword(s):  
Nucleic Acid ◽  
Single Nucleotide Polymorphisms ◽  
Peptide Nucleic Acid ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Clear Cut ◽  
Nuclease S1

Imaging analysis of EGFR mutated cancer cells using peptide nucleic acid (PNA)–DNA probes

The Analyst ◽  
2019 ◽  
Vol 144 (15) ◽  
pp. 4613-4621 ◽  
Author(s):  
Hajime Shigeto ◽  
Takashi Ohtsuki ◽  
Akira Iizuka ◽  
Yasuto Akiyama ◽  
Shohei Yamamura
Keyword(s):  
Nucleic Acid ◽  
Cancer Cells ◽  
Gene Mutation ◽  
Peptide Nucleic Acid ◽  
Dna Probes ◽  
Imaging Analysis ◽  
Single Nucleotide ◽  
Different Types ◽  
Egfr Mutated

PNA–DNA probes for detecting different types of EGFR mRNA harboring single nucleotide gene mutation were developed.

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