An Integrated Imaging Probe Design: The Synthesis of99mTc/Re-Containing Macrocyclic Peptide Scaffolds

2014 ◽  
Vol 21 (2) ◽  
pp. 568-578 ◽  
Author(s):  
Jennifer L. Hickey ◽  
Emily J. Simpson ◽  
Jinqiang Hou ◽  
Leonard G. Luyt
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Peptide Scaffolds ◽  
Macrocyclic Peptide

Frontispiece: An Integrated Imaging Probe Design: The Synthesis of99mTc/Re-Containing Macrocyclic Peptide Scaffolds

2015 ◽  
Vol 21 (2) ◽  
pp. n/a-n/a
Author(s):  
Jennifer L. Hickey ◽  
Emily J. Simpson ◽  
Jinqiang Hou ◽  
Leonard G. Luyt
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Peptide Scaffolds ◽  
Macrocyclic Peptide

scholarly journals Techniques for Molecular Imaging Probe Design

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly
Keyword(s):  
Molecular Imaging ◽  
Target Selection ◽  
Relevant Information ◽  
Probe Design ◽  
Imaging Probe ◽  
Molecular Imaging Probes ◽  
Genomics And Proteomics ◽  
Imaging Probes ◽  
Molecular Imaging Probe ◽  
Underlying Mechanisms

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.

The effect of backbone flexibility on site-selective modification of macrocycles

2016 ◽  
Vol 14 (43) ◽  
pp. 10230-10237 ◽  
Author(s):  
Conor C. G. Scully ◽  
Christopher J. White ◽  
Andrei K. Yudin
Keyword(s):  
Ring Opening ◽  
Backbone Flexibility ◽  
Peptide Scaffolds ◽  
Site Selective ◽  
Macrocyclic Peptide

The interplay of rotatable backbone torsions determines the ring-opening regioselectivity of electrophilic aziridines in macrocyclic peptide scaffolds.

scholarly journals Corrigendum: Exocyclic Control of Turn Induction in Macrocyclic Peptide Scaffolds

2014 ◽  
Vol 20 (11) ◽  
pp. 2983-2983
Author(s):  
Serge Zaretsky ◽  
Conor C. G. Scully ◽  
Alan J. Lough ◽  
Andrei K. Yudin
Keyword(s):  
Peptide Scaffolds ◽  
Macrocyclic Peptide

Exocyclic Control of Turn Induction in Macrocyclic Peptide Scaffolds

2013 ◽  
Vol 19 (52) ◽  
pp. 17668-17672 ◽  
Author(s):  
Serge Zaretsky ◽  
Conor C. G. Scully ◽  
Alan J. Lough ◽  
Andrei K. Yudin
Keyword(s):  
Peptide Scaffolds ◽  
Macrocyclic Peptide

scholarly journals AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

Aggregate ◽  
2021 ◽  
Author(s):  
Sanaz Naghibi ◽  
Tong Chen ◽  
Amin Jamshidi Ghahfarokhi ◽  
Youhong Tang
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Protein Imaging

scholarly journals Metallic nanoparticles as synthetic building blocks for cancer diagnostics: from materials design to molecular imaging applications

2015 ◽  
Vol 3 (28) ◽  
pp. 5657-5672 ◽  
Author(s):  
Vincenzo Mirabello ◽  
David G. Calatayud ◽  
Rory L. Arrowsmith ◽  
Haobo Ge ◽  
Sofia I. Pascu
Keyword(s):  
Molecular Imaging ◽  
Medical Diagnosis ◽  
Metallic Nanoparticles ◽  
Building Blocks ◽  
Cancer Diagnostics ◽  
Probe Design ◽  
Degenerative Diseases ◽  
Imaging Probe ◽  
Molecular Imaging Probe ◽  
Synthetic Scaffolds

New perspectives on the efficiency of metallic nanoparticles as synthetic scaffolds for molecular imaging probe design and their use in medical diagnosis of degenerative diseases such as cancer.

scholarly journals Back Cover: AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

Aggregate ◽  
2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Sanaz Naghibi ◽  
Tong Chen ◽  
Amin Jamshidi Ghahfarokhi ◽  
Youhong Tang
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Back Cover ◽  
Protein Imaging
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