Rapid and Efficient Synthesis of Poly-Substituted Quinolines Assisted by p-Toluene Sulfonic Acid under Solvent-Free Conditions: Comparative Study of Microwave Irradiation versus Conventional Heating.

ChemInform ◽  
2006 ◽  
Vol 37 (22) ◽  
Author(s):  
Cheng-Sheng Jia ◽  
Ze Zhang ◽  
Shu-Jiang Tu ◽  
Guan-Wu Wang
Keyword(s):  
Microwave Irradiation ◽  
Comparative Study ◽  
Sulfonic Acid ◽  
Solvent Free ◽  
Conventional Heating ◽  
Efficient Synthesis ◽  
Toluene Sulfonic Acid ◽  
Solvent Free Conditions ◽  
Substituted Quinolines

1,3-Dibromo-5,5-dimethylhydantoin as a useful reagent for efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions

2009 ◽  
Vol 63 (1) ◽  
Author(s):  
Mohammad Abdollahi-Alibeik ◽  
Zahra Zaghaghi
Keyword(s):  
Microwave Irradiation ◽  
Ethyl Acetoacetate ◽  
Biginelli Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aliphatic Aldehydes ◽  
Solvent Free Conditions ◽  
High Yields

AbstractEfficient syntheses of 3,4-dihydropyrimidin-2-(1H)-ones and the corresponding thioxo derivatives using 1,3-dibromo-5,5-dimethylhydantoin (DBH) catalysis of a one-pot three-component Biginelli reaction of aldehydes, ethyl acetoacetate, and urea or thiourea under microwave irradiation are described. The advantages of this method are its short reaction times, high yields of the products, inexpensive and commercially available catalyst, and solvent-free conditions. Typical isolated yields exceed 70 % for arylaldehydes (9 examples) and aliphatic aldehydes (2 examples).

Natural organic acids promoted Beckmann rearrangement: Green and expeditious synthesis of amides under solvent-free conditions

2014 ◽  
Vol 68 (4) ◽  
Author(s):  
Sandeep Rohokale ◽  
Santosh Kote ◽  
Santosh Deshmukh ◽  
Shankar Thopate
Keyword(s):  
Microwave Irradiation ◽  
Organic Acids ◽  
Tartaric Acid ◽  
Reaction Rate ◽  
Beckmann Rearrangement ◽  
Solvent Free ◽  
Conventional Heating ◽  
Highly Efficient ◽  
Naturally Occurring ◽  
Solvent Free Conditions

AbstractNaturally occurring organic acids are reported to be highly efficient promoters of the Beckmann rearrangement. Citric, oxalic, tartaric, malic, succinic, malonic, and fumaric acids efficiently promote the Beckmann rearrangement under solvent-free conditions and thermal and microwave irradiation. Tartaric acid was found to be the best promoter of the Beckmann rearrangement under conventional conditions as well as under microwave irradiation. Compared with conventional heating, microwave irradiation provides higher reaction rate and slightly higher yields.

Efficient solvent-free synthesis of bis(indolyl)methanes on SiO2 solid support under microwave irradiation

2015 ◽  
Vol 69 (3) ◽  
Author(s):  
Da-Wei Zhang ◽  
Yu-Min Zhang ◽  
Yi-Liang Zhang ◽  
Tian-Qi Zhao ◽  
Hong-Wei Liu ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Aromatic Aldehydes ◽  
Solid Support ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
Solvent Free Conditions ◽  
Solvent Free Synthesis

AbstractAn efficient synthesis of bis(indolyl)methanes was developed. Bis(indolyl)methanes were synthesized starting from various aromatic aldehydes with indole under microwave irradiation and solvent-free conditions (85-98 %). Solid support SiO

Sign in / Sign up

Export Citation Format

Share Document