ChemInform Abstract: Long-Chain 2H-Azirines with Heterogeneous Terminal Halogenation from the Marine Sponge Dysidea fragilis.

ChemInform ◽  
2008 ◽  
Vol 39 (34) ◽  
Author(s):  
Colin K. Skepper ◽  
Tadeusz F. Molinski
ChemBioChem ◽  
2007 ◽  
Vol 8 (14) ◽  
pp. 1729-1735 ◽  
Author(s):  
Satoko Matsunaga ◽  
Ryuichi Sakai ◽  
Mitsuru Jimbo ◽  
Hisao Kamiya

1988 ◽  
Vol 29 (21) ◽  
pp. 2506 ◽  
Author(s):  
Peter Karuso ◽  
Paul J. Scheuer
Keyword(s):  

1987 ◽  
Vol 28 (40) ◽  
pp. 4633-4636 ◽  
Author(s):  
Peter Karuso ◽  
Paul J. Scheuer
Keyword(s):  

Marine Drugs ◽  
2020 ◽  
Vol 18 (7) ◽  
pp. 350 ◽  
Author(s):  
Pierre-Eric Campos ◽  
Gaëtan Herbette ◽  
Christophe Chendo ◽  
Patricia Clerc ◽  
Florent Tintillier ◽  
...  

Chemical study of the CH2Cl2−MeOH (1:1) extract from the sponge Haliclona sp. collected in Mayotte highlighted three new long-chain highly oxygenated polyacetylenes, osirisynes G-I (1–3) together with the known osirisynes A (4), B (5), and E (6). Their structures were elucidated by 1D and 2D NMR spectra and HRESIMS and MS/MS data. All compounds were evaluated on catalase and sirtuin 1 activation and on CDK7, proteasome, Fyn kinase, tyrosinase, and elastase inhibition. Five compounds (1; 3–6) inhibited proteasome kinase and two compounds (5–6) inhibited CDK7 and Fyn kinase. Osirisyne B (5) was the most active compound with IC50 on FYNB kinase, CDK7 kinase, and proteasome inhibition of 18.44 µM, 9.13 µM, and 0.26 µM, respectively.


Lipids ◽  
1988 ◽  
Vol 23 (11) ◽  
pp. 1037-1048 ◽  
Author(s):  
Mishelle P. Lawson ◽  
Janice E. Thompson ◽  
Carl Djerassi

2020 ◽  
Vol 83 (9) ◽  
pp. 2769-2775
Author(s):  
Raku Irie ◽  
Masayoshi Miyahara ◽  
Shota Nakamura ◽  
Akito Honda ◽  
Ryuichi Sakai ◽  
...  

2021 ◽  
pp. 153437
Author(s):  
Li-Li Hong ◽  
Jie Wang ◽  
Li-Yun Liu ◽  
Fan Sun ◽  
Jia-Bao Sun ◽  
...  

Author(s):  
A. C. Reimschuessel ◽  
V. Kramer

Staining techniques can be used for either the identification of different polymers or for the differentiation of specific morphological domains within a given polymer. To reveal morphological features in nylon 6, we choose a technique based upon diffusion of the staining agent into accessible regions of the polymer.When a crystallizable polymer - such as nylon 6 - is cooled from the melt, lamellae form by chainfolding of the crystallizing long chain macromolecules. The regions between adjacent lamellae represent the less ordered amorphous domains into which stain can diffuse. In this process the lamellae will be “outlined” by the dense stain, giving rise to contrast comparable to that obtained by “negative” staining techniques.If the cooling of the polymer melt proceeds relatively slowly - as in molding operations - the lamellae are usually arranged in a radial manner. This morphology is referred to as spherulitic.


Author(s):  
J.T. Fourie

Contamination in electron microscopes can be a serious problem in STEM or in situations where a number of high resolution micrographs are required of the same area in TEM. In modern instruments the environment around the specimen can be made free of the hydrocarbon molecules, which are responsible for contamination, by means of either ultra-high vacuum or cryo-pumping techniques. However, these techniques are not effective against hydrocarbon molecules adsorbed on the specimen surface before or during its introduction into the microscope. The present paper is concerned with a theory of how certain physical parameters can influence the surface diffusion of these adsorbed molecules into the electron beam where they are deposited in the form of long chain carbon compounds by interaction with the primary electrons.


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